Technical Review of Clinical Outcomes Assessments Across the Continuum of Alzheimer's Disease

Autor: Dana B. DiBenedetti, Heather Menne, Russ Paulsen, Holly B. Krasa, George Vradenburg, Meryl Comer, Leigh F. Callahan, John Winfield, Michele Potashman, Kim Heithoff, Ann Hartry, Dorothee Oberdhan, Hilary Wilson, Deborah L. Hoffman, Dan Wieberg, Ian N. Kremer, Geraldine A. Taylor, James M. Taylor, Debra Lappin, Allison D. Martin, Brett Hauber, Carla Romano

Publikováno v: Neurology and Therapy, Vol 12, Iss 2, Pp 571-595 (2023)

Abstract Introduction Insight into the relationship between concepts that matter to the people affected by Alzheimer’s disease (AD) and the clinical outcome assessments (COAs) commonly used in AD clinical studies is limited. Phases 1 and 2 of the W

Externí odkaz: https://doaj.org/article/4563c68c02c441bda9571595e1d88641

Economic and caregiver impact of Alzheimer’s disease across the disease spectrum: a cohort study

Autor: Virginie Dauphinot, Michele Potashman, Mihaela Levitchi-Benea, Ray Su, Ivana Rubino, Pierre Krolak-Salmon

Publikováno v: Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2022)

Abstract Background Alzheimer’s disease (AD) substantially increases health-related costs. This study investigates direct medical costs and characterizes the caregiver burden across AD stages. Methods This study analyzed data from the French Primar

Externí odkaz: https://doaj.org/article/4555e4dbde5f4f22b10248a9de86c97b

The incidence of mild cognitive impairment: A systematic review and data synthesis

Autor: Cai Gillis, Fariba Mirzaei, Michele Potashman, M. Arfan Ikram, Nancy Maserejian

Publikováno v: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 248-256 (2019)

Abstract Introduction Incidence estimates of mild cognitive impairment (MCI) range widely. We obtained contemporary age‐specific MCI incidence rates and examined sources of heterogeneity. Methods We conducted a systematic review of population‐bas

Externí odkaz: https://doaj.org/article/a6815e14c1b445c39e5edd0014988c0d

Patient Concept Elicitation Interviews: Insights into Multiple System Atrophy (MSA) Patient Experiences and Relevance of a modified United Multiple System Atrophy Rating Scale (P8-9.003)

Autor: Michele Potashman, Isabella Huang, Susan Durham, Victoria Wirtz, Gilbert L’Italien, Vladimir Coric, Andrea De Palma, Triza Brion, Günter Höglinger, Horacio Kaufmann, Phillip Low, Nikolaus McFarland, Wassilios Meissner, Patricio Millar Vernetti, Huw Morris, Werner Poewe, Klaus Seppi, Wolfgang Singer, Steven Vernino, Irfan Qureshi

Publikováno v: Tuesday, April 25.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c8999efe0dc23689c2d3401097276d68
https://doi.org/10.1212/wnl.0000000000202288

What outcomes are important to patients with mild cognitive impairment or Alzheimer's disease, their caregivers, and health-care professionals?

Autor: Christophe Bintener, Michael Sharwood Smith, Michele Potashman, Amanda Ly, Alex McKeown, Christoph Jindra, Anders Gustavsson, Emilse Roncancio-Diaz, Cathie Sudlow, Olin Janssen, Anna Ponjoan, Claire Tochel, Stephanie J.B. Vos, Isabella Friis Jørgensen, Buket Öztürk, Catherine Reed, Josep Garre-Olmo, Mia Nelson, Christin Bexelius, Helen Baldwin, Enrico R. Fantoni

Publikováno v: Tochel, C, Smith, M, Baldwin, H, Gustavsson, A, Ly, A, Bexelius, C, Nelson, M, Bintener, C, Fantoni, E, Garre-Olmo, J, Janssen, O, Jindra, C, Jørgensen, I F, McKeown, A, Öztürk, B, Ponjoan, A, Potashman, M H, Reed, C, Roncancio-Diaz, E, Vos, S & Sudlow, C 2019, ' What outcomes are important to patients with mild cognitive impairment or Alzheimer's disease, their caregivers, and health-care professionals? A systematic review ', Alzheimer's & Dementia, vol. 11, pp. 231-247 . https://doi.org/10.1016/j.dadm.2018.12.003
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
Alzheimers & Dementia: Diagnosis, Assessment & Disease Monitoring
Tochel, C, Smith, M, Baldwin, H, Gustavsson, A, Ly, A, Bexelius, C, Nelson, M, Bintener, C, Fantoni, E, Garre-Olmo, J, Janssen, O, Jindra, C, Jorgensen, I, McKeown, A, Ozturk, B, Ponjoan, A, Potashman, M, Reed, C, Roncancio-Diaz, E, Vos, S & Sudlow, C 2019, ' What outcomes are important to patients with mild cognitive impairment or Alzheimer's disease, their caregivers, and health-care professionals? A systematic review ', Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring . https://doi.org/10.1016/j.dadm.2018.12.003
Tochel, C, Smith, M, Baldwin, H, Gustavsson, A, Ly, A, Bexelius, C, Nelson, M, Bintener, C, Fantoni, E, Garre-Olmo, J, Janssen, O, Jindra, C, Jørgensen, I F, McKeown, A, Öztürk, B, Ponjoan, A, Potashman, M H, Reed, C, Roncancio-Diaz, E, Vos, S, Sudlow, C & ROADMAP consortium 2019, ' What outcomes are important to patients with mild cognitive impairment or Alzheimer's disease, their caregivers, and health-care professionals? A systematic review ', Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, vol. 11, pp. 231-247 . https://doi.org/10.1016/j.dadm.2018.12.003
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 11(1), 231-247. Elsevier BV
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 231-247 (2019)

Introduction: Clinical trials involving patients with Alzheimer’s disease (AD) continue to try to identify disease-modifying treatments. Although trials are designed to meet regulatory and registration requirements, many do not measure outcomes of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b9fc902e29a50872ed92ca7654b159
https://cris.maastrichtuniversity.nl/en/publications/0f468330-2ae5-4972-b0a4-e3b057ce4213