Zobrazeno 1 - 10 of 80 pro vyhledávání: '"Michele, Paessler"'
1
Akademický článek
CAR T-cell therapy is effective for CD19-dim B-lymphoblastic leukemia but is impacted by prior blinatumomab therapy
Autor: Vinodh Pillai, Kavitha Muralidharan, Wenzhao Meng, Asen Bagashev, Derek A. Oldridge, Jaclyn Rosenthal, John Van Arnam, Jos J. Melenhorst, Diwakar Mohan, Amanda M. DiNofia, Minjie Luo, Sindhu Cherian, Jonathan R. Fromm, Gerald Wertheim, Andrei Thomas-Tikhonenko, Michele Paessler, Carl H. June, Eline T. Luning Prak, Vijay G. Bhoj, Stephan A. Grupp, Shannon L. Maude, Susan R. Rheingold
Publikováno v: Blood Advances, Vol 3, Iss 22, Pp 3539-3549 (2019)
Abstract: Tisagenlecleucel, a chimeric antigen receptor (CAR) T-cell product targeting CD19 is approved for relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL). However, the impact of pretreatment variables, such as CD19 expression level,
Externí odkaz: https://doaj.org/article/e70ab1bdc076485da3ba01a3a1e59b84
Zobrazit plný text záznamu
2
Akademický článek
Rhabdomyosarcoma and Wilms tumors contain a subpopulation of noggin producing, myogenic cells immunoreactive for lens beaded filament proteins.
Autor: Jacquelyn Gerhart, Kathryn Behling, Michele Paessler, LaBraya Milton, Gregory Bramblett, Denise Garcia, Meghan Pitts, Reginald Hurtt, Mitchell Crawford, Richard Lackman, Daniela Nguyen, Joseph Infanti, Paul FitzGerald, Mindy George-Weinstein
Publikováno v: PLoS ONE, Vol 14, Iss 4, p e0214758 (2019)
Myo/Nog cells are identified by their expression of the skeletal muscle specific transcription factor MyoD and the bone morphogenetic protein inhibitor noggin, and binding of the G8 monoclonal antibody. Their release of noggin is critical for morphog
Externí odkaz: https://doaj.org/article/f57b05f07b554d968ea74a7c538b2df5
Zobrazit plný text záznamu
4
Absolute lymphocyte count proliferation kinetics after CAR T-cell infusion impact response and relapse
Autor: Vinodh Pillai, Xiaoming Xu, Stephan A. Grupp, Sophia Faude, Vijay Bhoj, Shannon L. Maude, Kavitha Muralidharan, Michele Paessler, Susan R. Rheingold, Jane Wei, Gerald Wertheim
Publikováno v: Blood Adv
CD19-directed chimeric antigen receptor (CAR) T cells show characteristic proliferation kinetics after infusion that correlate with response. Clearance of circulating disease, B-cell aplasia (BCA), and cytokine release syndrome (CRS) are used to obse
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936e57e53f3145f33af08fa6ae9bd975
https://doi.org/10.1182/bloodadvances.2020004038
Zobrazit plný text záznamu
5
Diagnostic Challenges in Pediatric Hemophagocytic Lymphohistiocytosis
Autor: Neil Romberg, Michele P. Lambert, Kathleen E. Sullivan, Hamid Bassiri, Jasmyn Atalla, David T. Teachey, Edward J Behrens, Sarah K. Tasian, Michele Paessler, Stephanie J Si, Reema T. Patel, Brian T. Fisher
Publikováno v: Journal of Clinical Immunology
Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of severe immune dysregulation that encompasses a broad range of underlying genetic diseases and infectious triggers. Monogenic conditions, autoimmune diseases, and infections can all drive the p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60423d64541706d1ba73c88b65585aa
http://europepmc.org/articles/PMC7988244
Zobrazit plný text záznamu
6
Characterization of Plasmacytoid Dendritic Cells, Microbial Sequences, and Identification of a Candidate Public T-Cell Clone in Kikuchi-Fujimoto Disease
Autor: Wenzhao Meng, Geraldine S. Pinkus, Nya D Nelson, Aaron M. Rosenfeld, Gerald Wertheim, Michele Paessler, Jason Nomburg, Eline T. Luning Prak, Susan Bullman, Vinodh Pillai, Matthew Meyerson, Chandra Sekhar Pedamallu, Jason L. Hornick
Publikováno v: Pediatric and Developmental Pathology. 24:193-205
Objectives Kikuchi-Fujimoto disease (KFD) is a self-limited lymphadenitis of unclear etiology. We aimed to further characterize this disease in pediatric patients, including evaluation of the CD123 immunohistochemical (IHC) staining and investigation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b66a55eb2791660909286830b901f5
https://doi.org/10.1177/1093526620987961
Zobrazit plný text záznamu
10
Haematology laboratory parameters to assess efficacy of CD19-, CD22-, CD33-, and CD123-directed chimeric antigen receptor T-cell therapy in haematological malignancies
Autor: Bradley, Drumheller, Kirubel, Gebre, Brian, Lockhart, Elizabeth, Margolskee, Amrom, Obstfeld, Michele, Paessler, Vinodh, Pillai
Publikováno v: International journal of laboratory hematologyREFERENCES. 44(4)
Chimeric antigen receptor (CAR) T cell products are available to treat relapsed/refractory B-lymphoblastic leukaemia/lymphoma (B-ALL), diffuse large B-cell lymphoma, mantle-cell lymphoma, and myeloma. CAR products vary by their target epitope and con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b671a60e9322e1e5dac71003c1309467
https://pubmed.ncbi.nlm.nih.gov/35419923
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje