Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Michele, Kyle"'
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 827 (2024)
Alzheimer’s disease (AD) leads to progressive neurodegeneration and dementia. AD primarily affects older adults with neuropathological changes including amyloid-beta (Aβ) deposition, neuroinflammation, and neurodegeneration. We have previously dem
Externí odkaz:
https://doaj.org/article/a596bc30578740079732c2b08f217e65
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-25 (2021)
Abstract Traumatic brain injury (TBI) is a major cause of long-term disability in young adults. An evidence-based treatment for TBI recovery, especially in the chronic phase, is not yet available. Using a severe TBI mouse model, we demonstrate that t
Externí odkaz:
https://doaj.org/article/7caf3b1737454fd8b47cdbfbe248b01e
Publikováno v:
Cells, Vol 12, Iss 5, p 705 (2023)
Severe traumatic brain injury (TBI) causes long-term disability and death in young adults. White matter is vulnerable to TBI damage. Demyelination is a major pathological change of white matter injury after TBI. Demyelination, which is characterized
Externí odkaz:
https://doaj.org/article/159114c851f24654a2944d90c1d4e983
Publikováno v:
Neurobiology of Disease, Vol 132, Iss , Pp - (2019)
Cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) is a cerebral small vascular disease caused by NOTCH3 gene mutation in vascular smooth muscle cells (VSMCs), leading to ischemic stroke and vascular d
Externí odkaz:
https://doaj.org/article/0103d51b30eb40979fb9bc15ab163ae5
Publikováno v:
ASN Neuro, Vol 8 (2016)
Stroke, a leading cause of adult disability in the world, is a severe medical condition with limited treatment. Physical therapy, the only treatment available for stroke rehabilitation, appears to be effective within 6 months post-stroke. Here, we ha
Externí odkaz:
https://doaj.org/article/d640174845d44ff98599c6a08d0de997
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-25 (2021)
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-25 (2021)
Traumatic brain injury (TBI) is a major cause of long-term disability in young adults. An evidence-based treatment for TBI recovery, especially in the chronic phase, is not yet available. Using a severe TBI mouse model, we demonstrate that the neuror
Background Traumatic brain injury (TBI) is a major cause of death and disability in young adults worldwide. TBI-induced long-term cognitive deficits represent a growing clinical problem.Stem cell factor (SCF) and granulocyte-colony stimulating factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ff7821de65d4ab2146c6a6db5309a7
https://doi.org/10.21203/rs.2.17381/v2
https://doi.org/10.21203/rs.2.17381/v2
Publikováno v:
Journal of Neurosurgery. 129:1286-1294
OBJECTIVETraumatic brain injury (TBI) is a major cause of long-term disability and death in young adults. The lack of pharmaceutical therapy for post–acute TBI recovery remains a crucial medical challenge. Stem cell factor (SCF) and granulocyte col
Publikováno v:
Journal of neurotrauma. 37(7)
S100 calcium-binding protein A9 (S100a9), a proinflammatory protein, has been shown to be involved in the development of neuroinflammatory disorders and neurodegenerative diseases. Upregulation of S100a9 in the brain during acute brain injury has bee
Publikováno v:
Neurobiology of Disease, Vol 132, Iss, Pp-(2019)
Cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) is a cerebral small vascular disease caused by NOTCH3 gene mutation in vascular smooth muscle cells (VSMCs), leading to ischemic stroke and vascular d