Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Michele, Galluccio"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8743 (2024)
OCTN1 and OCTN2 are membrane transport proteins encoded by the SLC22A4 and SLC22A5 genes, respectively. Even though several transcripts have been predicted by bioinformatics for both genes, only one functional protein isoform has been described for e
Externí odkaz:
https://doaj.org/article/cc006afc6aee4619a910bceb7d659af2
Autor:
Lorena Pochini, Michele Galluccio, Lara Console, Mariafrancesca Scalise, Ivano Eberini, Cesare Indiveri
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 392 (2024)
Inflammation is a physiological condition characterized by a complex interplay between different cells handled by metabolites and specific inflammatory-related molecules. In some pathological situations, inflammation persists underlying and worsening
Externí odkaz:
https://doaj.org/article/e599cf5177134ca3acc91aecbac10af1
Autor:
Raffaella Scanga, Mariafrancesca Scalise, Nadia Marino, Francesco Parisi, Donatella Barca, Michele Galluccio, Chiara Brunocilla, Lara Console, Cesare Indiveri
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107738- (2023)
Summary: LAT1 (SLC7A5) is one of the most studied membrane transporters due to its relevance to physiology in supplying essential amino acids to brain and fetus, and to pathology being linked to nervous or embryo alterations; moreover, LAT1 over-expr
Externí odkaz:
https://doaj.org/article/2c6b32186c104dc4b75d4121490c9b2f
Autor:
Michele Galluccio, Tiziano Mazza, Mariafrancesca Scalise, Martina Tripicchio, Martina Scarpelli, Maria Tolomeo, Lorena Pochini, Cesare Indiveri
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 536 (2023)
The human SLC7A10 transporter, also known as ASC-1, catalyzes the transport of some neutral amino acids. It is expressed in astrocytes, neurons, and adipose tissues, playing roles in learning, memory processes, and lipid metabolism, thus being involv
Externí odkaz:
https://doaj.org/article/ae5ff6eeaff844d6896f8442518ef610
Autor:
Michele Galluccio, Mariafrancesca Scalise, Gilda Pappacoda, Martina Scarpelli, Marcella Bonanomi, Daniela Gaglio, Cesare Indiveri
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The plasma membrane transporter xCT belongs to the SLC7 family and has the physiological role of mediating the exchange of glutamate and cystine across the cell plasma membrane, being crucial for redox control. The xCT protein forms a heterodimer wit
Externí odkaz:
https://doaj.org/article/ffbb16f3aaeb405dbb9c097aaf9b1a9a
Autor:
Raffaella Scanga, Mariafrancesca Scalise, Filomena Rovella, Teresa Maria Rosaria Regina, Michele Galluccio, Cesare Indiveri
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The plasma membrane transporter LAT1 (SLC7A5) is a crucial player for cell homeostasis because it is responsible for providing cells with essential amino acids and hormones. LAT1 forms a functional heterodimer with the cell surface antigen heavy chai
Externí odkaz:
https://doaj.org/article/a7b7d998af894c0eb6d9ee66e5218d91
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 15, Iss 2, Pp 207-219 (2020)
Among the different targets of administered drugs, there are membrane transporters that play also a role in drug delivery and disposition. Moreover, drug-transporter interactions are responsible for off-target effects of drugs underlying their toxici
Externí odkaz:
https://doaj.org/article/f883f6cb800c48c7ae49977680f80502
Publikováno v:
ACS Omega, Vol 5, Iss 5, Pp 2069-2080 (2020)
Externí odkaz:
https://doaj.org/article/b6d06f7dea814a11a04687bbf6c6f317
Autor:
Lorena Pochini, Michele Galluccio
Publikováno v:
Life, Vol 12, Iss 8, p 1206 (2022)
For more than 20 years, yeast has been a widely used system for the expression of human membrane transporters. Among them, more than 400 are members of the largest transporter family, the SLC superfamily. SLCs play critical roles in maintaining cellu
Externí odkaz:
https://doaj.org/article/b21aa3ee008e4686b5687036cfcdc3a5
Autor:
Michele Galluccio, Lara Console, Lorena Pochini, Mariafrancesca Scalise, Nicola Giangregorio, Cesare Indiveri
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3823 (2022)
Ten percent of human genes encode for membrane transport systems, which are key components in maintaining cell homeostasis. They are involved in the transport of nutrients, catabolites, vitamins, and ions, allowing the absorption and distribution of
Externí odkaz:
https://doaj.org/article/6ba1845077364a13ac4b43a319874a8b