Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Michelangelo, Foti"'
Autor:
Diana Gomes, Cyril Sobolewski, Stéphanie Conzelmann, Tifany Schaer, Etienne Lefai, Dulce Alfaiate, Eirini D. Tseligka, Nicolas Goossens, Caroline Tapparel, Francesco Negro, Michelangelo Foti, Sophie Clément
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Chronic hepatitis C (CHC) is associated with the development of metabolic disorders, including both hepatic and extra-hepatic insulin resistance (IR). Here, we aimed at identifying liver-derived factor(s) potentially inducing peripheral IR a
Externí odkaz:
https://doaj.org/article/a040a358d8ae4ba69685c5dd95b1ac81
Autor:
Mehdi Badaoui, Cyril Sobolewski, Alexandre Luscher, Marc Bacchetta, Thilo Köhler, Christian van Delden, Michelangelo Foti, Marc Chanson
Publikováno v:
JCI Insight, Vol 8, Iss 3 (2023)
Cystic fibrosis (CF) is characterized by chronic bacterial infections leading to progressive bronchiectasis and respiratory failure. Pseudomonas aeruginosa (Pa) is the predominant opportunistic pathogen infecting the CF airways. The guanine nucleotid
Externí odkaz:
https://doaj.org/article/4535e110c636422783a845e741aa6c15
Autor:
Marta Correia de Sousa, Etienne Delangre, Miranda Türkal, Michelangelo Foti, Monika Gjorgjieva
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4914 (2023)
The endoplasmic reticulum is an organelle exerting crucial functions in protein production, metabolism homeostasis and cell signaling. Endoplasmic reticulum stress occurs when cells are damaged and the capacity of this organelle to perform its normal
Externí odkaz:
https://doaj.org/article/323414cd7d594017b6229b6ecbb98b73
Autor:
Monika Gjorgjieva, Anne-Sophie Ay, Marta Correia de Sousa, Etienne Delangre, Dobrochna Dolicka, Cyril Sobolewski, Christine Maeder, Margot Fournier, Christine Sempoux, Michelangelo Foti
Publikováno v:
Cells, Vol 11, Iss 18, p 2860 (2022)
MiR-22 is mostly considered as a hepatic tumor-suppressor microRNA based on in vitro analyses. Yet, whether miR-22 exerts a tumor-suppressive function in the liver has not been investigated in vivo. Herein, in silico analyses of miR-22 expression wer
Externí odkaz:
https://doaj.org/article/e586bccd94ae4c939070d578c9dd7af0
Autor:
Etienne Delangre, Ezia Oppliger, Serkan Berkcan, Monika Gjorgjieva, Marta Correia de Sousa, Michelangelo Foti
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11030 (2022)
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent and slow progressing hepatic pathology characterized by different stages of increasing severity which can ultimately give rise to the development of hepatocellular carcinoma (HCC). Besid
Externí odkaz:
https://doaj.org/article/204f738054a04f4080b3831eb5fc25fd
Autor:
Beatrice Kaufmann, Philippa Boulle, Flavien Berthou, Margot Fournier, David Beran, Iza Ciglenecki, Malcolm Townsend, Guillaume Schmidt, Maya Shah, Susanna Cristofani, Philippe Cavailler, Michelangelo Foti, Leonardo Scapozza
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0245372 (2021)
Strict storage recommendations for insulin are difficult to follow in hot tropical regions and even more challenging in conflict and humanitarian emergency settings, adding an extra burden to the management of people with diabetes. According to pharm
Externí odkaz:
https://doaj.org/article/2e25da4b681d4a8c923bdc0ae88084d6
Autor:
Flavien Berthou, Cyril Sobolewski, Daniel Abegg, Margot Fournier, Christine Maeder, Dobrochna Dolicka, Marta Correia de Sousa, Alexander Adibekian, Michelangelo Foti
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3959 (2022)
Liver-derived circulating factors deeply affect the metabolism of distal organs. Herein, we took advantage of the hepatocyte-specific PTEN knockout mice (LPTENKO), a model of hepatic steatosis associated with increased muscle insulin sensitivity and
Externí odkaz:
https://doaj.org/article/8ee15058d76c484e9069db329c8790f1
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9428 (2021)
Stress granules (SGs) are small membrane-free cytosolic liquid-phase ordered entities in which mRNAs are protected and translationally silenced during cellular adaptation to harmful conditions (e.g., hypoxia, oxidative stress). This function is achie
Externí odkaz:
https://doaj.org/article/86ea4043918f44fd93bc434339f74ab6
Autor:
Dobrochna Dolicka, Cyril Sobolewski, Marta Correia de Sousa, Monika Gjorgjieva, Michelangelo Foti
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6648 (2020)
AU-rich element-binding proteins (AUBPs) represent important post-transcriptional regulators of gene expression. AUBPs can bind to the AU-rich elements present in the 3’-UTR of more than 8% of all mRNAs and are thereby able to control the stability
Externí odkaz:
https://doaj.org/article/014f8b476ee844d9a3097a0275cfc97e
Publikováno v:
PPAR Research, Vol 2017 (2017)
Peroxisome proliferator-activated receptors (PPARs) are a family of ligand-dependent nuclear receptors, which control the transcription of genes involved in energy homeostasis and inflammation and cell proliferation/differentiation. Alterations of PP
Externí odkaz:
https://doaj.org/article/c3374fbb0eb349b8a8c7187d5361add1