Dual Oncogenic/Anti-Oncogenic Role of PATZ1 in FRTL5 Rat Thyroid Cells Transformed by the

Autor: Michela, Vitiello, Giuseppe, Palma, Mario, Monaco, Anna Maria, Bello, Simona, Camorani, Paola, Francesca, Domenica, Rea, Antonio, Barbieri, Gennaro, Chiappetta, Gabriella De, Vita, Laura, Cerchia, Claudio, Arra, Monica, Fedele

Publikováno v: Genes

PATZ1 is a transcriptional factor downregulated in thyroid cancer whose re-expression in thyroid cancer cells leads to a partial reversion of the malignant phenotype, including the capacity to proliferate, migrate, and undergo epithelial-to-mesenchym

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2bac573b8a6e1fa6fe91faf8977cfd88
https://pubmed.ncbi.nlm.nih.gov/30744101

Loss of One or Two PATZ1 Alleles Has a Critical Role in the Progression of Thyroid Carcinomas Induced by the RET/PTC1 Oncogene

Autor: Emilia Vuttariello, Monica Fedele, Michela Vitiello, Laura Cerchia, Claudio Arra, Barbara D’Andrea, Gennaro Chiappetta, Anna Capiluongo, Alfredo Fusco, Mario Monaco, Giuseppe Palma, Antonio Luciano

Publikováno v: Cancers, Vol 10, Iss 4, p 92 (2018)
Cancers; Volume 10; Issue 4; Pages: 92
Cancers

POZ/BTB and AT-hook-containing zinc finger protein 1 (PATZ1) is an emerging cancer-related gene that is downregulated in different human malignancies, including thyroid cancer, where its levels gradually decrease going from papillary thyroid carcinom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e414032a6a50120ab9aec2703f306c7e
http://www.mdpi.com/2072-6694/10/4/92

Transcriptional and post-transcriptional regulation of transmembrane protein 132A

Autor: Azumi Sone, Takahiro Hikiji, Kentaro Oh-hashi, Shinsuke Ishigaki, Gen Sobue, Kazutoshi Kiuchi, Yoko Hirata, Michela Vitiello, Monica Fedele

Publikováno v: Molecular and cellular biochemistry 405 (2015): 291–299. doi:10.1007/s11010-015-2419-x
info:cnr-pdr/source/autori:Oh-hashi, Kentaro; Sone, Azumi; Hikiji, Takahiro; Hirata, Yoko; Vitiello, Michela; Fedele, Monica; Ishigaki, Shinsuke; Sobue, Gen; Kiuchi, Kazutoshi/titolo:Transcriptional and post-transcriptional regulation of transmembrane protein 132A/doi:10.1007%2Fs11010-015-2419-x/rivista:Molecular and cellular biochemistry/anno:2015/pagina_da:291/pagina_a:299/intervallo_pagine:291–299/volume:405

Transmembrane protein 132A (TMEM132A) was first isolated from rat brain using PCR-selected cDNA subtraction, and it was found to be predominantly expressed in the brain. However, the transcriptional regulation of the TMEM132A gene has not been fully

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0a1a97497b34f8d7849e95601d85b4
https://doi.org/10.1007/s11010-015-2419-x

PATZ1 is a new prognostic marker of glioblastoma associated with the stem-like phenotype and enriched in the proneural subtype

Autor: Paolo Cappabianca, Michela Vitiello, Giorgio Borrelli, Marialaura Del Basso De Caro, Paola Francesca, Simona Camorani, Federica Caponnetto, Monica Fedele, Marialuisa Califano, Daniela Cesselli, Elvira Crescenzi, Claudio Arra, Laura Cerchia, Gaetano Calì, Elia Guadagno

Publikováno v: Oncotarget 8 (2017): 59282–59300. doi:10.18632/oncotarget.19546
info:cnr-pdr/source/autori:Guadagno, Elia; Vitiello, Michela; Francesca, Paola; Cali, Gaetano; Caponnetto, Federica; Cesselli, Daniela; Camorani, Simona; Borrelli, Giorgio; Califano, Marialuisa; Cappabianca, Paolo; Arra, Claudio; Crescenzi, Elvira; Cerchia, Laura; De Caro, Maria Laura Del Basso; Fedele, Monica/titolo:PATZ1 is a new prognostic marker of glioblastoma associated with the stem-like phenotype and enriched in the proneural subtype/doi:10.18632%2Foncotarget.19546/rivista:Oncotarget/anno:2017/pagina_da:59282/pagina_a:59300/intervallo_pagine:59282–59300/volume:8
Oncotarget

// Elia Guadagno 1 , Michela Vitiello 2 , Paola Francesca 2 , Gaetano Cali 2 , Federica Caponnetto 3 , Daniela Cesselli 3 , Simona Camorani 2 , Giorgio Borrelli 1 , Marialuisa Califano 1 , Paolo Cappabianca 4 , Claudio Arra 5 , Elvira Crescenzi 2 , L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4afc4043d6692149d2c251a89948b136
http://www.cnr.it/prodotto/i/375946

PATZ1 is a target of miR-29b that is induced by Ha-Ras oncogene in rat thyroid cells

Autor: Teresa Valentino, Paola Francesca, Michela Vitiello, Alfredo Fusco, Gabriella De Vita, Elvira Crescenzi, Claudio Arra, Monica Fedele, Laura Cerchia, Domenica Rea, Marta De Menna

Publikováno v: Scientific reports (Nature Publishing Group) 6 (2016). doi:10.1038/srep25268
info:cnr-pdr/source/autori:Vitiello M.; Valentino T.; De Menna M.; Crescenzi E.; Francesca P.; Rea D.; Arra C.; Fusco A.; De Vita G.; Cerchia L.; Fedele M./titolo:PATZ1 is a target of miR-29b that is induced by Ha-Ras oncogene in rat thyroid cells/doi:10.1038%2Fsrep25268/rivista:Scientific reports (Nature Publishing Group)/anno:2016/pagina_da:/pagina_a:/intervallo_pagine:/volume:6
Scientific Reports

The regulatory transcriptional factor PATZ1 is constantly downregulated in human thyroid cancer where it acts as a tumour suppressor by targeting p53-dependent genes involved in Epithelial-Mesenchymal Transition and cell migration. The aim of the pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502150864ee3bbb32cc7aebc2937f091