Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michela V. Pavan"'
Autor:
Antonio Varnavas, Federico Berti, Theodoros Markidis, Francesco Makovec, Laura Mennuni, George Kokotos, Lucia Lassiani, Michela V. Pavan
Publikováno v:
Bioorganic & Medicinal Chemistry. 17:2336-2350
The anthranilic acid diamides represent the more recent class of nonpeptide CCK(1) receptor antagonists. This class is characterized by the presence of anthranilic acid, used as a molecular scaffold, and two pharmacophores selected from the C-termina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db791ac364cb18aa427415ab456a8e83
https://doi.org/10.1016/j.bmc.2009.02.012
https://doi.org/10.1016/j.bmc.2009.02.012
Autor:
Michela V. Pavan, Antonio Varnavas, Lucia Lassiani, Dimitra Hadjipavlou-Litina, Paolo Braiuca
Publikováno v:
Bioorganicmedicinal chemistry. 17(14)
A research is presented on quantitative structure-activity relationship (QSAR) studies on the more recent class of non-peptidic CCK(1) receptor antagonists. Our results suggest that the balance of hydrophobicity and volume dependent polarizability te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0727cfbd4250ad2fec92193bf42e62b
https://pubmed.ncbi.nlm.nih.gov/19523833
https://pubmed.ncbi.nlm.nih.gov/19523833
Autor:
Federico Berti, Laura Mennuni, Lucia Lassiani, Flora Ferrari, Alessia Ciogli, Francesco Makovec, Daniel Fourmy, Antonio Varnavas, Chantal Escrieut, Giorgio Stefancich, Francesco Gasparrini, Esther Marco, Michela V. Pavan
The anthranilic acid diamides represent the most recent class of nonpeptide CCK(1) receptor (CCK(1)-R) antagonists. Herein we describe the second phase of the anthranilic acid C-terminal optimization using nonproteinogenic amino acids containing a ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d53c4bddd1e8d47f015714250acdc23
http://hdl.handle.net/11573/390098
http://hdl.handle.net/11573/390098
The synthesis of optically active 4-methyl-5-n-butyl- and 5-n-pentylpyrrolidin-2-ones, aza analogues of the corresponding Quercus lactones, has been achieved by a chemoenzymatic procedure, involving in the enantiodifferentiating step the enzymatic ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9972d2a03023266ced67d016e7edc763
https://hdl.handle.net/11368/1693773
https://hdl.handle.net/11368/1693773
Autor:
Michela V. Pavan, Lucia Lassiani, Federico Berti, Giorgio Stefancich, Alessia Ciogli, Francesco Gasparrini, Laura Mennuni, Flora Ferrari, Chantal Escrieut, Esther Marco, Francesco Makovec, Daniel Fourmy, Antonio Varnavas
Publikováno v:
Journal of Medicinal Chemistry; Aug2011, Vol. 54 Issue 16, p5769-5785, 17p