Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Michela Saviana"'
Autor:
Michela Saviana, Giulia Romano, Joseph McElroy, Giovanni Nigita, Rosario Distefano, Robin Toft, Federica Calore, Patricia Le, Daniel Del Valle Morales, Sarah Atmajoana, Stephen Deppen, Kai Wang, L. James Lee, Mario Acunzo, Patrick Nana-Sinkam
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionSmall cell lung cancer (SCLC) is characterized by poor prognosis and challenging diagnosis. Screening in high-risk smokers results in a reduction in lung cancer mortality, however, screening efforts are primarily focused on non-small cell
Externí odkaz:
https://doaj.org/article/fde62c5e48d0426982529ada7d2ce1ad
Autor:
Emanuela Rizzello, Domenico Pimpinella, Annabella Pignataro, Giulia Titta, Elisabetta Merenda, Michela Saviana, Giovanni Francesco Porcheddu, Chiara Paolantoni, Francesca Malerba, Corinna Giorgi, Giulia Curia, Silvia Middei, Cristina Marchetti
Publikováno v:
Neurobiology of Disease, Vol 181, Iss , Pp 106106- (2023)
Epilepsy is a comorbidity associated with Alzheimer's disease (AD), often starting many years earlier than memory decline. Investigating this association in the early pre-symptomatic stages of AD can unveil new mechanisms of the pathology as well as
Externí odkaz:
https://doaj.org/article/59eee80ed5da48d7a674b8cffa2e0e3c
Autor:
Michela Saviana, Patricia Le, Lavender Micalo, Daniel Del Valle-Morales, Giulia Romano, Mario Acunzo, Howard Li, Patrick Nana-Sinkam
Publikováno v:
Genes, Vol 14, Iss 5, p 1075 (2023)
miRNAs are some of the most well-characterized regulators of gene expression. Integral to several physiological processes, their aberrant expression often drives the pathogenesis of both benign and malignant diseases. Similarly, DNA methylation repre
Externí odkaz:
https://doaj.org/article/90dce119f07b40668a8e003b4d9a8747
Autor:
Samira Shojaee, Giulia Romano, Trinidad M. Sanchez, Gulmira Yermakhanova, Michela Saviana, Patricia Le, Giovanni Nigita, Federica Calore, Rachel Guthrie, Kathryn Hess, Le Kang, Theresa Swift-Scanlan, Jacob T. Graham, Najib M. Rahman, Patrick S. Nana-Sinkam, Mario Acunzo
Publikováno v:
Genes, Vol 13, Iss 11, p 2159 (2022)
Lung and breast cancer are the two most common causes of malignant pleural effusion (MPE). MPE diagnosis plays a crucial role in determining staging and therapeutic interventions in these cancers. However, our understanding of the pathogenesis and pr
Externí odkaz:
https://doaj.org/article/e244d5f5a5b04d8f85b74d1837ed8c2e
Autor:
Daniel del Valle-Morales, Patricia Le, Michela Saviana, Giulia Romano, Giovanni Nigita, Patrick Nana-Sinkam, Mario Acunzo
Publikováno v:
Genes, Vol 13, Iss 7, p 1289 (2022)
The epitranscriptome encompasses all post-transcriptional modifications that occur on RNAs. These modifications can alter the function and regulation of their RNA targets, which, if dysregulated, result in various diseases and cancers. As with other
Externí odkaz:
https://doaj.org/article/96f1379601e7427da1380ca27e387fda
Autor:
Giulia Romano, Giovanni Nigita, Federica Calore, Michela Saviana, Patricia Le, Carlo M. Croce, Mario Acunzo, Patrick Nana-Sinkam
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Lung cancer is the leading cause of cancer mortality worldwide. Increased understanding of the molecular mechanisms of the disease has led to the development of novel therapies and improving outcomes. Recently, extracellular vesicles (EVs) have emerg
Externí odkaz:
https://doaj.org/article/c8a75e20e5b34949bad8cd80c87695a2
Publikováno v:
Cancers, Vol 13, Iss 22, p 5633 (2021)
Extracellular vesicles (EVs) are heterogenous membrane-encapsulated vesicles secreted by every cell into the extracellular environment. EVs carry bioactive molecules, including proteins, lipids, DNA, and different RNA forms, which can be internalized
Externí odkaz:
https://doaj.org/article/476fcc03045142a99dd13a3fe751746a
Autor:
Giulia Romano, Michela Saviana, Patricia Le, Howard Li, Lavender Micalo, Giovanni Nigita, Mario Acunzo, Patrick Nana-Sinkam
Publikováno v:
Cancers, Vol 12, Iss 7, p 1845 (2020)
In the last two decades, RNA post-transcriptional modifications, including RNA editing, have been the subject of increasing interest among the scientific community. The efforts of the Human Genome Project combined with the development of new sequenci
Externí odkaz:
https://doaj.org/article/b7f673d8abe84fd0bec13ba39344cbbb
Autor:
Giulia Romano, Patricia Le, Giovanni Nigita, Michela Saviana, Lavender Micalo, Francesca Lovat, Daniel del Valle Morales, Howard Li, Patrick Nana-Sinkam, Mario Acunzo
Publikováno v:
Oncogene. 42:1597-1606
Autor:
Mario Acunzo, Giulia Romano, Patricia Le, Giovanni Nigita, Michela Saviana, Lavender Micalo, Francesca Lovat, Daniel del Valle Morales, Howard Li, Patrick Nana-Sinkam
The epidermal growth factor receptor (EGFR) is a tyrosine kinase receptor (TKR) frequently mutated in lung cancer. Despite initially favorable clinical responses of non-small cell lung cancer (NSCLC) patients harboring an EGFR mutation to treatment w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23cddef38713166a9556e9a3df86a502
https://doi.org/10.21203/rs.3.rs-1957094/v1
https://doi.org/10.21203/rs.3.rs-1957094/v1