Výsledky vyhledávání - "Michela Paradisi"

Human Mesenchymal Stem Cells Produce Bioactive Neurotrophic Factors: Source, Individual Variability and Differentiation Issues

Autor: Alessandro Giuliani, Stefania Pirondi, Luciana Giardino, Laura Bonsi, Francesco Alviano, G. Lizzo, Roberta Costa, Cosetta Marchionni, Michela Paradisi, Mercedes Fernandez, Giacomo Lanzoni, Laura Calzà

Publikováno v: Scopus-Elsevier
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Europe PubMed Central

The possible use of cell therapies for neurological lesions and disorders is regarded as a very promising strategy. However, many issues related to cell type, tissue donor, expected biological action etc., are still open. In this study human mesenchy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a92c0ceb44700a5ca67bf17df3f454e
https://doi.org/10.1177/039463201402700309

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Functional and molecular evidence of myelin- and neuroprotection by thyroid hormone administration in experimental allergic encephalomyelitis

Autor: G. D’Intino, Ml Dell’Acqua, Sandra Sivilia, M. M. Filippi, Marina Pizzi, Laura Calzà, Patrizio Pasqualetti, P.M. Rossini, Luciana Giardino, Michela Paradisi, Cristina Baiguera, Valentina Panetta, Luca Lorenzini

Publikováno v: Neuropathology and Applied Neurobiology. 38:454-470

M. L. Dell'Acqua, L. Lorenzini, G. D'Intino, S. Sivilia, P. Pasqualetti, V. Panetta, M. Paradisi, M. M. Filippi, C. Baiguera, M. Pizzi, L. Giardino, P. M. Rossini and L. Calza (2012) Neuropathology and Applied Neurobiology38, 454–470 Functional and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e246f155b05f0f1fecacf7ec953835d3
https://doi.org/10.1111/j.1365-2990.2011.01228.x

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A single prenatal exposure to the endocrine disruptor 2,3,7,8-tetrachlorodibenzo-p-dioxin alters developmental myelination and remyelination potential in the rat brain

Autor: Sandra Sivilia, Luciana Giardino, Laura Calzà, Michela Paradisi, G. D’Intino, Mercedes Fernandez, G. Del Vecchio

Publikováno v: Journal of Neurochemistry. 115:897-909

J. Neurochem. (2010) 115, 897–909. Abstract Polychlorinated dibenzo-dioxins, furans and dioxin-like polychlorinated biphenyls are ubiquitous in foodstuffs of animal origin and accumulate in the fatty tissues of animals and humans. The most toxic co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc3dbce1e3d276145d656adafb5b6440
https://doi.org/10.1111/j.1471-4159.2010.06974.x

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Ex vivo study of dentate gyrus neurogenesis in human pharmacoresistant temporal lobe epilepsy

Autor: Gianluca Marucci, Michela Paradisi, G. Lizzo, G. Del Vecchio, Giacomo Lanzoni, Luciana Giardino, Mercedes Fernandez, Tiziana Antonelli, Eugenio Pozzati, Marco Giulioni, Laura Calzà, Gian Paolo Bagnara

Publikováno v: Neuropathology and Applied Neurobiology. 36:535-550

M. Paradisi, M. Fernandez, G. Del Vecchio, G. Lizzo, G. Marucci, M. Giulioni, E. Pozzati, T. Antonelli, G. Lanzoni, G. P. Bagnara, L. Giardino and L. Calza (2010) Neuropathology and Applied Neurobiology36, 535–550 Ex vivo study of dentate gyrus neu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ceec7dd060013586405ccb581bb1c73
https://doi.org/10.1111/j.1365-2990.2010.01102.x

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Thyroid hormone induces glial lineage of primary neurospheres derived from non‐pathological and pathological rat brain: implications for remyelination‐enhancing therapies

Autor: G. Del Vecchio, Mercedes Fernandez, Luciana Giardino, Laura Calzà, Michela Paradisi

Publikováno v: International Journal of Developmental Neuroscience. 27:769-778

Thyroid hormone exerts a critical role in developmental myelination, acting on the production and maturation of oligodendrocyte, and on the expression of genes encoding for myelin protein. Since remyelination is considered a recapitulation of cellula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8e7a06dc8253fc51f04918e3af04d8
https://doi.org/10.1016/j.ijdevneu.2009.08.011

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Neural stem cells isolated from amyloid precursor protein-mutated mice for drug discovery

Autor: Luciana Giardino, Michela Paradisi, Laura Calzà, Giulia Lizzo, Mercedes Fernandez, Vito Antonio Baldassarro

AIM: To develop an in vitro model based on neural stem cells derived from transgenic animals, to be used in the study of pathological mechanisms of Alzheimer’s disease and for testing new molecules. METHODS: Neural stem cells (NSCs) were isolated f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5e81f55a850bc18cfaf0a31931b82b
http://hdl.handle.net/11585/398504

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Prenatal glucocorticoid exposure affects learning and vulnerability of cholinergic neurons

Autor: Luciana Giardino, Michela Paradisi, Mercedes Fernandez, Laura Calzà, Mia Emgård, Stefania Pirondi

Publikováno v: Neurobiology of aging. 28(1)

Prenatal treatment with synthetic glucocorticoids is commonly used as a treatment for women at risk of preterm delivery. However, little is known about the life-long consequences of these treatments on the fetus. In the present study, we evaluated co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da9cf7b47ba97834bf247b19b9ddc16
https://pubmed.ncbi.nlm.nih.gov/16406151

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Cognitive deficit associated with cholinergic and nerve growth factor down-regulation in experimental allergic encephalomyelitis in rats

Autor: G. D’Intino, Michela Paradisi, Alessandro Giuliani, Luigi Aloe, Laura Calzà, Mercedes Fernandez, Luciana Giardino

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 102(8)

Clinical symptoms in multiple sclerosis include cognitive dysfunction. Difficulties in learning and remembering new information represent the most common cognitive deficit and are associated with a general and progressive brain pathology. Possible pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93faf5b41ed623fd16ab9c0c16b25ecd
https://pubmed.ncbi.nlm.nih.gov/15710875

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Thyroid hormone and remyelination in adult central nervous system: a lesson from an inflammatory-demyelinating disease

Autor: Luciana Giardino, Alessandro Giuliani, Nadia DeSordi, Sandra Sivilia, G. D’Intino, Stefania Pirondi, Michela Paradisi, Laura Calzà, Mercedes Fernandez

Publikováno v: Brain research. Brain research reviews. 48(2)

Re-myelination in the adult CNS has been demonstrated in different experimental models of demyelinating diseases. However, there is no clear evidence that re-myelination is effective in multiple sclerosis (MS), the most diffuse demyelinating disease.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0adb9146695bd02ba942c9840b8874ae
https://pubmed.ncbi.nlm.nih.gov/15850672

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