Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Michela Milan"'
Publikováno v:
ACS Central Science, Vol 3, Iss 12, Pp 1350-1358 (2017)
Externí odkaz:
https://doaj.org/article/0447b8e5fd464fd99132d784c71d0f43
Publikováno v:
ACS Central Science, Vol 3, Iss 3, Pp 196-204 (2017)
Externí odkaz:
https://doaj.org/article/2dfdec6ddd304fab9948bf431730ff13
Autor:
Michela Milani, Cesare Canepari, Simone Assanelli, Simone Merlin, Ester Borroni, Francesco Starinieri, Mauro Biffi, Fabio Russo, Anna Fabiano, Desirèe Zambroni, Andrea Annoni, Luigi Naldini, Antonia Follenzi, Alessio Cantore
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 6, Pp 1427-1450 (2024)
Abstract Lentiviral vectors (LV) are efficient vehicles for in vivo gene delivery to the liver. LV integration into the chromatin of target cells ensures their transmission upon proliferation, thus allowing potentially life-long gene therapy followin
Externí odkaz:
https://doaj.org/article/b045f6dbf8624a8e8e0b19badc7c0b7b
Publikováno v:
Accounts of Chemical Research. 51:1984-1995
Aliphatic C–H bond functionalization is at the frontline of research because it can provide straightforward access to simplified and cost-effective synthetic procedures. A number of these methodologies are based on hydrogen atom transfer (HAT), whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7aba4e1e6d5fc95b43a1d97495a672
https://doi.org/10.1021/acs.accounts.8b00231
https://doi.org/10.1021/acs.accounts.8b00231
Publikováno v:
The Journal of Organic Chemistry. 82:13542-13549
A kinetic study on the hydrogen atom transfer (HAT) reactions from the aliphatic C–H bonds of a series of 1-Z-pentyl, 1-Z-propyl, and Z-cyclohexyl derivatives and of a series of N-alkylamides and N-alkylphthalimides to the electrophilic cumyloxyl r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac09832cdaf30b314e00b11e63a33f28
https://doi.org/10.1021/acs.joc.7b02654
https://doi.org/10.1021/acs.joc.7b02654
Publikováno v:
ACS Catalysis. 7:5903-5911
Site selective C–H oxidation of N-alkylamides and phthalimides with aqueous hydrogen peroxide catalyzed by manganese complexes is described. These catalysts are shown to exhibit substantially improved performance in product yields and substrate sco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd99f3ea0e73921af9b60394538d0103
https://doi.org/10.1021/acscatal.7b02151
https://doi.org/10.1021/acscatal.7b02151
Publikováno v:
Organic letters. 20(9)
Substituted N-cyclohexyl amides undergo aliphatic C–H bond oxidation with H2O2 catalyzed by manganese complexes. The reactions are directed by torsional effects leading to site-selective oxidation of cis-1,4-, trans-1,3-, and cis-1,2-cyclohexanedia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83fc3a49fc2c4fac7a5c19abc1783a90
https://pubmed.ncbi.nlm.nih.gov/29676920
https://pubmed.ncbi.nlm.nih.gov/29676920
Enantioselective aliphatic C-H bond oxidation simultaneously installs functionality and chirality into hydrocarbon units, converting in a single step readily available, inexpensive and typically inert hydrocarbons into precious building blocks for or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eea644f69b60be275c20b1a3fbe2155
http://hdl.handle.net/2108/210578
http://hdl.handle.net/2108/210578
Publikováno v:
The Journal of Organic Chemistry. 79:7179-7184
A time-resolved kinetic study of the hydrogen atom transfer (HAT) reactions from a series of alkanamides to the cumyloxyl radical (CumO(•)) was carried out. With N,N-dialkylformamides HAT preferentially occurs from the formyl C-H bond, while in N-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfac64bc124f2eff6c904bf87b9a55d7
https://doi.org/10.1021/jo5013459
https://doi.org/10.1021/jo5013459
Autor:
Naphang Ho, Shiwani Agarwal, Michela Milani, Alessio Cantore, Christian J. Buchholz, Frederic B. Thalheimer
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 144-156 (2022)
Pre-clinical humanized mouse models are a powerful tool to evaluate immunotherapies. NSG-SGM3 mice reconstituted with human stem cells (huSGM3) develop pronounced human myeloid cells due to transgenic expression of stem cell factor, granulocyte-macro
Externí odkaz:
https://doaj.org/article/e78a0da4c10e4bfabac0ead54b2a2f99