Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Michela M. Pellizzoni"'
Autor:
Michela M. Pellizzoni, Thomas R. Ward, Boris Lozhkin, Ryan L. Peterson, Laura Tiessler-Sala, Fadri Christoffel, Nico V. Igareta, Agustí Lledós, Jean-Didier Maréchal, Daniel C. Spiess
Publikováno v:
Nature Catalysis
Artificial metalloenzymes result from anchoring an organometallic catalyst within an evolvable protein scaffold. Thanks to its dimer of dimers quaternary structure, streptavidin allows the precise positioning of two metal cofactors to activate a sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2b248aa5ab22ba6fc2fc9266ccba29
https://doi.org/10.1038/s41929-021-00651-9
https://doi.org/10.1038/s41929-021-00651-9
Autor:
Andriy Lubskyy, Chao Guo, Robert J. Chadwick, Alke Petri-Fink, Nico Bruns, Michela M. Pellizzoni
Myoglobin was subjected to site-directed mutagenesis and transformed into a catalyst able to perform atom transfer radical cyclisation reactions, i.e. intramolecular atom transfer radical additions. Replacing the iron-coordinating histidine with seri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf4f478f5e315538dcb29165e7b9be3
https://strathprints.strath.ac.uk/82491/1/Lubskyy_etal_CC_2022_Engineered_myoglobin_as_a_catalyst_for_atom_transfer_radical_cyclisation.pdf
https://strathprints.strath.ac.uk/82491/1/Lubskyy_etal_CC_2022_Engineered_myoglobin_as_a_catalyst_for_atom_transfer_radical_cyclisation.pdf
Autor:
Chao Guo, Robert J. Chadwick, Adam Foulis, Giada Bedendi, Andriy Lubskyy, Kyle J. Rodriguez, Michela M. Pellizzoni, Ross D. Milton, Rebecca Beveridge, Nico Bruns
Publikováno v:
ChemBioChem. 23
Myoglobin (Mb) can react with hydrogen peroxide (H 2O 2) to form a highly active intermediate compound and catalyse oxidation reactions. To enhance this activity, known as pseudo-peroxidase activity, previous studies have focused on the modification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6a6ad539ca76c0aa4cfff74e65eea4
https://doi.org/10.1002/cbic.202200197
https://doi.org/10.1002/cbic.202200197
Autor:
Kyle J. Rodriguez, Bernadetta Gajewska, Michela M. Pellizzoni, Csaba Fodor, Nico Bruns, Jonas Pollard
Publikováno v:
ACS Macro Letters
Reversible-deactivation radical polymerizations (controlled radical polymerizations) have revolutionized and revitalized the field of polymer synthesis. While enzymes and other biologically derived catalysts have long been known to initiate free radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bcdec880f57cd70fb078e00dfaf0e31
https://pubmed.ncbi.nlm.nih.gov/35632946
https://pubmed.ncbi.nlm.nih.gov/35632946
Autor:
Michela M. Pellizzoni, Andriy Lubskyy
Publikováno v:
Reference Module in Chemistry, Molecular Sciences and Chemical Engineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a37adfe13783b982343b0e185ddf139
https://doi.org/10.1016/b978-0-12-820206-7.00065-2
https://doi.org/10.1016/b978-0-12-820206-7.00065-2
Autor:
Sven Panke, Markus Jeschek, Michela M. Pellizzoni, Thomas R. Ward, Fadri Christoffel, Tobias Vornholt
Publikováno v:
bioRxiv
Science Advances, 7 (4)
Science Advances, 7 (4)
Artificial metalloenzymes (ArMs) catalyzing new-to-nature reactions could play an important role in transitioning toward a sustainable economy. While ArMs have been created for various transformations, attempts at their genetic optimization have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e540f0438edc4327d504695d6dd04a8c
Autor:
Fadri Christoffel, Nico V. Igareta, Michela M. Pellizzoni, Laura Tiessler-Sala, Boris Lozhkin, Daniel C. Spiess, Agustí Lledós, Jean-Didier Maréchal, Ryan L. Peterson, Thomas R. Ward
Publikováno v:
Nature Catalysis. 5:354-354
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baecac162c7a561e0147ad830bfcd6ea
https://doi.org/10.1038/s41929-022-00790-7
https://doi.org/10.1038/s41929-022-00790-7
Autor:
Omar Rifaie-Graham, Ashley Djuhadi, Nico Bruns, Michela M. Pellizzoni, Sandor Balog, Kyle J. Rodriguez, Jonas Pollard, Samuel Raccio
The fight against tropical diseases such as malaria requires the development of innovative biosensing techniques. Diagnostics must be rapid and robust to ensure prompt case management and to avoid further transmission. The malaria biomarker hemozoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f786b74468285b0f1e0fa4608e9f4066
https://strathprints.strath.ac.uk/73955/7/Raccio_etal_Analyst_2020_Rapid_quantification_of_the_malaria_biomarker_hemozoin_by_improved.pdf
https://strathprints.strath.ac.uk/73955/7/Raccio_etal_Analyst_2020_Rapid_quantification_of_the_malaria_biomarker_hemozoin_by_improved.pdf
Autor:
Kyle J, Rodriguez, Michela M, Pellizzoni, Mohammad, Divandari, Edmondo M, Benetti, Nico, Bruns
Publikováno v:
Methods in enzymology. 627
The promiscuity of enzymes allows for their implementation as catalysts for non-native chemical transformations. Utilizing the redox activity of metalloenzymes under activator regenerated by electron transfer (ARGET) ATRP conditions, well-controlled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e590617199f9866181e0b20cfab8856
https://pubmed.ncbi.nlm.nih.gov/31630744
https://pubmed.ncbi.nlm.nih.gov/31630744
Publikováno v:
Methods in enzymology. 627
In this chapter, we highlight the use of horseradish peroxidase (HRP) as a catalyst to initiate free radical polymerizations of vinyl monomers under benign reaction conditions. A variety of vinyl monomers, including 4-acryloylmorpholine (AM), 2-hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d2ae074ae1d84499eddc675f2ff607e
https://pubmed.ncbi.nlm.nih.gov/31630743
https://pubmed.ncbi.nlm.nih.gov/31630743