Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michela L. Garabedian"'
Autor:
Maud Voisin, Elina Shrestha, Claire Rollet, Cyrus A. Nikain, Tatjana Josefs, Mélanie Mahé, Tessa J. Barrett, Hye Rim Chang, Rachel Ruoff, Jeffrey A. Schneider, Michela L. Garabedian, Chris Zoumadakis, Chi Yun, Bara Badwan, Emily J. Brown, Adam C. Mar, Robert J. Schneider, Ira J. Goldberg, Inés Pineda-Torra, Edward A. Fisher, Michael J. Garabedian
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-18 (2021)
Voisin et al. show that reducing phosphorylation at serine 196 of LXRα (LXRα pS196) in hematopoietic cells attenuates atherosclerosis and obesity of mice fed a high-fat diet. They find that the transcriptional activity of LXRα is reprogrammed in m
Externí odkaz:
https://doaj.org/article/c5802b4ff1e54135a67ab96e212ab5fd
Autor:
Ada Weinstock, Karishma Rahman, Or Yaacov, Hitoo Nishi, Prashanthi Menon, Cyrus A Nikain, Michela L Garabedian, Stephanie Pena, Naveed Akbar, Brian E Sansbury, Sean P Heffron, Jianhua Liu, Gregory Marecki, Dawn Fernandez, Emily J Brown, Kelly V Ruggles, Stephen A Ramsey, Chiara Giannarelli, Matthew Spite, Robin P Choudhury, P'ng Loke, Edward A Fisher
Publikováno v:
eLife, Vol 10 (2021)
Atherosclerosis is a disease of chronic inflammation. We investigated the roles of the cytokines IL-4 and IL-13, the classical activators of STAT6, in the resolution of atherosclerosis inflammation. Using Il4-/-Il13-/- mice, resolution was impaired,
Externí odkaz:
https://doaj.org/article/c161388cdc5a4ae69a76b07070902db1
Autor:
Bianca Scolaro, Emily J. Brown, Franziska Krautter, Marie Petitjean, Casey Donahoe, Stephanie Pena, Michela L. Garabedian, Cyrus A. Nikain, Maria Laskou, Ozlem Tufanli, Carmen Hannemann, Myriam Aouadi, Ada Weinstock, Edward A. Fisher
While weight loss is highly recommended for those with obesity, >60% will regain their lost weight. This weight cycling is associated with elevated risk of cardiovascular disease, relative to never having lost weight. How weight loss/regaindirectlyin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d15132407a356469451679452e813ef
https://doi.org/10.1101/2023.05.07.539777
https://doi.org/10.1101/2023.05.07.539777
Autor:
Chiara Giannarelli, Stephanie Pena, Robin P. Choudhury, Matthew Spite, Naveed Akbar, Stephen A. Ramsey, Karishma Rahman, Or Yaacov, Emily J. Brown, Kelly V. Ruggles, Dawn M. Fernandez, Gregory Marecki, Edward A. Fisher, Michela L. Garabedian, P'ng Loke, Sean P. Heffron, Prashanthi Menon, Cyrus A Nikain, Brian E. Sansbury, Jianhua Liu, Hitoo Nishi, Ada Weinstock
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Atherosclerosis is a disease of chronic inflammation. We investigated the roles of the cytokines IL-4 and IL-13, the classical activators of STAT6, in the resolution of atherosclerosis inflammation. Using Il4-/-Il13-/- mice, resolution was impaired,
Autor:
Robin P. Choudhury, Karishma Rahman, Gregory Marecki, Chiara Giannarelli, Brian E. Sansbury, Jianhua Liu, Stephanie Pena, Cyrus A Nikain, Michela L. Garabedian, Emily J. Brown, Kelly V. Ruggles, Dawn M. Fernandez, Edward A. Fisher, Or Yaacov, P'ng Loke, Sean P. Heffron, Prashanthi Menon, Naveed Akbar, Matthew Spite, Stephen A. Ramsey, Hitoo Nishi, Ada Weinstock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56ade9e551d4a0ce2a619f62a277cc24
https://doi.org/10.7554/elife.67932.sa2
https://doi.org/10.7554/elife.67932.sa2
Autor:
Melanie Mahe, Hye Rim Chang, Maud Voisin, Michael J. Garabedian, Adam C. Mar, Ira J. Goldberg, Chi Yun, Cyrus A Nikain, Claire Rollet, Robert J. Schneider, Rachel Ruoff, Chris Zoumadakis, Bara Badwan, Michela L. Garabedian, Emily J. Brown, Elina Shrestha, Tatjana Josefs, Edward A. Fisher, Jeffrey A. Schneider, Tessa J. Barrett, Ines Pineda-Torra
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-18 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-18 (2021)
Atherosclerosis and obesity share pathological features including inflammation mediated by innate and adaptive immune cells. LXRα plays a central role in the transcription of inflammatory and metabolic genes. LXRα is modulated by phosphorylation at
Autor:
Emily J. Brown, Maud Voisin, Tatjana Josefs, Edward A. Fisher, Ira J. Goldberg, Michela L. Garabedian, Elina Shrestha, Ines Pineda-Torra, Cyrus A Nikain, Claire Rollet, Hye Rim Chang, Michael J. Garabedian, Rachel Ruoff, Tessa J. Barrett
Atherosclerosis and obesity share pathological features including inflammation mediated by innate and adaptive immune cells. LXRα, a nuclear receptor, plays a central role in the transcription of inflammatory and lipid metabolic genes. LXRα is modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a4239ec0b57b59e8668886ac664cc12
https://doi.org/10.1101/2020.02.07.939090
https://doi.org/10.1101/2020.02.07.939090
Autor:
Michela L. Garabedian, Juan J. Lafaille, Stephanie Pena, Edward A. Fisher, Kathryn J. Moore, Emily J. Brown, Monika Sharma, Ada Weinstock
Publikováno v:
Immunometabolism. 1
Autor:
Ada Weinstock, Edward A. Fisher, Stephanie Pena, Michela L. Garabedian, Monika Sharma, Juan J. Lafaille, Emily J. Brown, Kathryn J. Moore
Publikováno v:
Immunometabolism
Obesity can lead to type 2 diabetes and is an epidemic. A major contributor to its adverse effects is inflammation of the visceral adipose tissue (VAT). Life-long caloric restriction (CR), in contrast, results in extended lifespan, enhanced glucose t
Publikováno v:
International Journal of Environmental Research and Public Health, Vol 18, Iss 3749, p 3749 (2021)
International Journal of Environmental Research and Public Health
Volume 18
Issue 7
International Journal of Environmental Research and Public Health
Volume 18
Issue 7
Little information is available regarding the glycemic effects of inorganic arsenic (iAs) exposure in urban populations. We evaluated the association of total arsenic and the relative proportions of arsenic metabolites in urine with glycemia as measu