Výsledky vyhledávání - "Michela Carbonatto"

Nonclinical safety, pharmacokinetics, and pharmacodynamics of atacicept

Autor: Derek Janszen, Enrico Vigna, Sergio Peano, Manuela Onidi, Mauro Bertolino, Rafael A. Ponce, Chiara Daghero, Laura Fava, Ping Yu, Jennifer Visich, Michela Carbonatto, Stephanie Steidler, Bruno Roattino, Stacey R. Dillon, Michele Ardizzone

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology. 105(1)

Atacicept, a soluble recombinant fusion protein of the human immunoglobulin (Ig) G1 Fc and the extracellular domain of the human transmembrane activator and calcium modulator and cyclophylin ligand interactor receptor, acts as an antagonist of both B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebffb6d514762f452a2d2bb2cc999cb
https://pubmed.ncbi.nlm.nih.gov/18522929

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Effects of apocynin and natural antioxidant from spinach on inducible nitric oxide synthase and cyclooxygenase-2 induction in lipopolysaccharide-induced hepatic injury in rat

Autor: Abraham Nyska, Robert R. Maronpot, Cindy R. Moomaw, Michela Carbonatto, Varda Ben Shaul, Liat Lomnitski, Shlomo Grossman, Julie F. Foley

Publikováno v: Pharmacologytoxicology. 87(1)

The immunoreactivity of inducible nitric oxide synthase, and cyclooxygenase-2 was compared among groups of male Wistar rats comprising those injected with lipopolysaccharide following pretreatment with either natural antioxidant from spinach or the a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d17fc224c5bf02316c2f5ecc2ef743
https://pubmed.ncbi.nlm.nih.gov/10987211

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Interleukin 6 knock-out mice are resistant to antigen-induced experimental arthritis

Autor: Ruben Papoian, Alessandra Boe, Ottaviano Serlupi-Crescenzi, Michela Carbonatto, Marta Baiocchi

Publikováno v: Cytokine. 11(12)

In order to assess the potential role of IL-6 in rheumatoid arthritis (RA), we have compared IL-6 deficient (IL-6 ko) mice and their wild-type (wt) counterpart for the capacity to develop methylated bovine serum albumin (mBSA)-induced arthritis. Our

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fdeea40c50daa95afa12a96f3fdc835
https://pubmed.ncbi.nlm.nih.gov/10623431

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Interference with heparin binding and oligomerization creates a novel anti-inflammatory strategy targeting the chemokine system

Autor: Valeria Muzio, Timothy N. C. Wells, Amir Smailbegovic, Matthias Mack, Rocco Cirillo, Marie Kosco-Vilbois, Zoë Johnson, Amanda E. I. Proudfoot, Clive P. Page, Suzanne Herren, Paola Zaratin, Rebecca Lever, Mark J. Rose, Michela Carbonatto

Publikováno v: Scopus-Elsevier
King's College London

A hallmark of autoimmunity and other chronic diseases is the overexpression of chemokines resulting in a detrimental local accumulation of proinflammatory immune cells. Chemokines play a pivotal role in cellular recruitment through interactions with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25b8cd8953b51e2a12b95a9f9abe396
http://www.scopus.com/inward/record.url?eid=2-s2.0-6344269426&partnerID=MN8TOARS