Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Michela Brazzoli"'
Autor:
Andrea Paola Mandelli, Greta Magri, Marco Tortoli, Stefania Torricelli, Donatello Laera, Fabio Bagnoli, Oretta Finco, Giuliano Bensi, Michela Brazzoli, Emiliano Chiarot
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Skin and soft tissue infections (SSTIs) are the most common diseases caused by Staphylococcus aureus (S. aureus), which can progress to threatening conditions due to recurrences and systemic complications. Staphylococcal protein A (SpA) is an immunom
Externí odkaz:
https://doaj.org/article/3ec8ea8c878f4f1ca3656bca627a82da
Autor:
Bruna Clemente, Maxime Denis, Camila Pedroso Silveira, Francesca Schiavetti, Michela Brazzoli, Daniela Stranges
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
With the deepening of our understanding of adaptive immunity at the cellular and molecular level, targeting antigens directly to immune cells has proven to be a successful strategy to develop innovative and potent vaccines. Indeed, it offers the pote
Externí odkaz:
https://doaj.org/article/86dda4ef929546eb870d32be678cf845
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 19, Iss 2 (2023)
Antimicrobial resistance (AMR) is considered by WHO one of the top ten public health threats. New control strategies involving concerted actions of both public and private sectors need to be developed. Vaccines play a major role in controlling the sp
Externí odkaz:
https://doaj.org/article/d0a3d3470de04d8793788548d80f20d7
Autor:
Serena Tondi, Emilio Siena, Ahmed Essaghir, Benoît Bozzetti, Viviane Bechtold, Aline Scaillet, Bruna Clemente, Mariateresa Marrocco, Chiara Sammicheli, Simona Tavarini, Francesca Micoli, Davide Oldrini, Alfredo Pezzicoli, Martina Di Fede, Michela Brazzoli, Cristina Ulivieri, Francesca Schiavetti
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1116 (2024)
Shigellosis, an acute gastroenteritis infection caused by Shigella species, remains a public health burden in developing countries. Recently, many outbreaks due to Shigella sonnei multidrug-resistant strains have been reported in high-income countrie
Externí odkaz:
https://doaj.org/article/7b1784f8e02347449e0d10d261f6c272
Autor:
Serena Tondi, Bruna Clemente, Carmen Esposito, Chiara Sammicheli, Simona Tavarini, Laura B. Martin, Omar Rossi, Francesca Micoli, Erika Bartolini, Michela Brazzoli, Cristina Ulivieri, Christoph J. Blohmke, Francesca Schiavetti
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Generalized Modules for Membrane Antigens (GMMA) are outer membrane exosomes purified from Gram-negative bacteria genetically mutated to increase blebbing and reduce risk of reactogenicity. This is commonly achieved through modification of the lipid
Externí odkaz:
https://doaj.org/article/6879890e38e54d8282d3f728473d5484
Autor:
Giulia Anderluzzi, Gustavo Lou, Simona Gallorini, Michela Brazzoli, Russell Johnson, Derek T. O’Hagan, Barbara C. Baudner, Yvonne Perrie
Publikováno v:
Vaccines, Vol 8, Iss 2, p 212 (2020)
messenger RNA (mRNA)-based vaccines combine the positive attributes of both live-attenuated and subunit vaccines. In order for these to be applied for clinical use, they require to be formulated with delivery systems. However, there are limited in vi
Externí odkaz:
https://doaj.org/article/aa2f6cee1fe640f292d76cc8327dbba4
Autor:
Diletta Magini, Cinzia Giovani, Simona Mangiavacchi, Silvia Maccari, Raffaella Cecchi, Jeffrey B Ulmer, Ennio De Gregorio, Andrew J Geall, Michela Brazzoli, Sylvie Bertholet
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161193 (2016)
Current hemagglutinin (HA)-based seasonal influenza vaccines induce vaccine strain-specific neutralizing antibodies that usually fail to provide protection against mismatched circulating viruses. Inclusion in the vaccine of highly conserved internal
Externí odkaz:
https://doaj.org/article/77a802e3a79e4914ac1f78ea1a9c72e3
Publikováno v:
International Journal of Hepatology, Vol 2011 (2011)
The Hepatitis C virus E1 and E2 envelope proteins are the major players in all events required for virus entry into target cells. In addition, the recently developed HCV cell culture system has indicated that E1E2 heterodimer formation is a prerequis
Externí odkaz:
https://doaj.org/article/e694af8a356e4a32895df274ee105bdf
Autor:
Emilio Siena, Francesca Schiavetti, Erica Borgogni, Marianna Taccone, Elisa Faenzi, Michela Brazzoli, Susanna Aprea, Monia Bardelli, Gianfranco Volpini, Francesca Buricchi, Chiara Sammicheli, Simona Tavarini, Viviane Bechtold, Christoph J. Blohmke, Dario Cardamone, Carlo De Intinis, Antonio Gonzalez-Lopez, Derek T. O'Hagan, Sandra Nuti, Claudia Seidl, Arnaud M Didierlaurent, Sylvie Bertholet, Ugo D'Oro, Duccio Medini, Oretta Finco
Publikováno v:
Vaccine.
The candidate Adjuvant System AS37 contains a synthetic toll-like receptor agonist (TLR7a) adsorbed to alum. In a phase I study (NCT02639351), healthy adults were randomised to receive one dose of licensed alum-adjuvanted meningococcal serogroup C (M
Autor:
Serena, Tondi, Bruna, Clemente, Carmen, Esposito, Chiara, Sammicheli, Simona, Tavarini, Laura B, Martin, Omar, Rossi, Francesca, Micoli, Erika, Bartolini, Michela, Brazzoli, Cristina, Ulivieri, Christoph J, Blohmke, Francesca, Schiavetti
Publikováno v:
Frontiers in cellular and infection microbiology. 12
Generalized Modules for Membrane Antigens (GMMA) are outer membrane exosomes purified from Gram-negative bacteria genetically mutated to increase blebbing and reduce risk of reactogenicity. This is commonly achieved through modification of the lipid