Výsledky vyhledávání - "Michela Bellini"

MnO Nanoparticles Embedded in Functional Polymers as T1 Contrast Agents for Magnetic Resonance Imaging

Autor: Davide Prosperi, Michele Mauri, Michela Bellini, Lucia Morelli, Pradip Das, Isabel García, Miriam Colombo, Roberto Simonutti, Fabio Corsi, Rany Rotem, Luis M. Liz-Marzán, Jesus Penaranda Avila, Marta Truffi, Veronica Collico

Publikováno v: ACS Applied Nano Materials. 3:3787-3797

The design and development of contrast agents (CAs) for magnetic resonance imaging (MRI) in clinical analysis is expected to improve the image spatial resolution and to increase the detection sensitivity, especially regarding neurological disorders a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8425e783b14d6d874b094e9b0da5b6
https://doi.org/10.1021/acsanm.0c00474

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Abstract P1-20-04: Nanoformulation of doxorubicin inside H- ferritin nanocages allows a cardio-safe combined therapy with trastuzumab: De-escalating cardiotoxicity in HER2-positive breast cancer

Autor: Fabio Corsi, Erika Longhi, Davide Prosperi, Marta Truffi, Michela Bellini, Serena Mazzucchelli, Matteo Monieri, Luca Sorrentino, Pietro Zerbi, R Ottria, Arianna Bonizzi, F. Andreata

Publikováno v: Cancer Research. 79:P1-20

Background: HER2+ breast cancer (BC) accounts for 20-25 % of BCs and it is characterized by high aggressiveness.1 Despite the anti-HER2 monoclonal antibody Trastuzumab (TZ) has improved BC clinical outcome, it could induce severe cardiac reversible d

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https://doi.org/10.1158/1538-7445.sabcs18-p1-20-04

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Does conjugation strategy matter? Cetuximab-conjugated gold nanocages for targeting triple-negative breast cancer cells

Autor: Svetlana Avvakumova, A. Sánchez Iglesias, Elisabetta Galbiati, Fabio Corsi, Raffaele Allevi, L. Moretto, Maria Antonietta Rizzuto, Michela Bellini, Davide Prosperi, Miriam Colombo, Laura Pandolfi, Enrica Soprano

Publikováno v: Nanoscale Advances. 1:3626-3638

The efficient targeting of cancer cells depends on the success of obtaining the active targeting of overexpressed receptors. A very accurate design of nanoconjugates should be done via the selection of the conjugation strategy to achieve effective ta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ae7777dc8921d20a10d47ba2640913
https://doi.org/10.1039/c9na00241c

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Development of an Effective Tumor-Targeted Contrast Agent for Magnetic Resonance Imaging Based on Mn/H-Ferritin Nanocomplexes

Autor: Lucia Salvioni, Miriam Colombo, Anna Degrassi, Massimiliano D’Arienzo, Davide Prosperi, Chiara Tullio, Stefania Garbujo, Michela Bellini, Luisa Fiandra, Filippo Testa, Rany Rotem

Publikováno v: ACS Applied Bio Materials

Magnetic resonance imaging (MRI) is one of the most sophisticated diagnostic tools that is routinely used in clinical practice. Contrast agents (CAs) are commonly exploited to afford much clearer images of detectable organs and to reduce the risk of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089ed4503c4eb500596e7cc80dfa937c
https://hdl.handle.net/10281/378184

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Impact of the strategy adopted for drug loading in nonporous silica nanoparticles on the drug release and cytotoxic activity

Autor: Svetlana Avvakumova, Barbara Colzani, Benedetta Riva, Davide Prosperi, Michela Bellini, Miriam Colombo, Annalisa Radeghieri, Carlo Morasso, Maria Antonietta Rizzuto, Eleonora Corvi, Paolo Verderio, Ewa Rozek

Publikováno v: Journal of Colloid and Interface Science. 519:18-26

Nanoparticles are normally classified as “hard”, mainly consisting of metal or metal oxide cores, or “soft”, including polymer-based, liposomes and biomimetic nanoparticles. Soft nanoparticles have been studied in depth for drug formulation a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bbf812bd1880e69e1b6eff318adb26a
https://doi.org/10.1016/j.jcis.2018.02.040

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Abstract P1-10-13: Olaparib nanoformulation in H-ferritin as a promising option for both BRCA-mutated and sporadic triple negative breast cancer: An in vitro study

Autor: Fabio Corsi, Maria Antonietta Rizzuto, Davide Prosperi, R Ottria, Marta Truffi, P Ciuffreda, Michela Bellini, Luca Sorrentino, Serena Mazzucchelli

Publikováno v: Cancer Research. 78:P1-10

Background: PolyADP-ribose polymerase (PARP) inhibitors are a novel promising strategy toward triple-negative breast cancer (TNBC), which often shows genomic instability or BRCA mutations. However, clinical results are controversial, and no benefits

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c9614b4b8ae876551da23326d354a8f
https://doi.org/10.1158/1538-7445.sabcs17-p1-10-13

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Abstract P4-06-09: Withdrawn

Autor: Davide Prosperi, Serena Mazzucchelli, Marta Truffi, F D'Addio, F. Andreata, Michela Bellini, Matteo Monieri, Luca Sorrentino, Fabio Corsi, A Gambaro

Publikováno v: Cancer Research. 79:P4-06

This abstract was withdrawn by the authors. Citation Format: Corsi F, Andreata F, Truffi M, Sorrentino L, D'Addio F, Monieri M, Gambaro A, Bellini M, Prosperi D, Mazzucchelli S. Withdrawn [abstract]. In: Proceedings of the 2018 San Antonio Breast Can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9513fd061659e74a2fe0314e0e4eb00
https://doi.org/10.1158/1538-7445.sabcs18-p4-06-09

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Abstract P6-12-17: H-ferritin allows nanometronomic treatment of breast cancer with doxorubicin preventing drug resistance and circumventing cardiotoxicity

Autor: Davide Prosperi, Erika Longhi, Marta Truffi, L. Fiandra, Luca Sorrentino, Serena Mazzucchelli, Michela Bellini, F.M.R. Corsi, Manuela Nebuloni, Maria Antonietta Rizzuto

Publikováno v: Cancer Research. 77:P6-12

Chemotherapeutic treatment of breast cancer is based on maximum tolerated dose (MTD) approach.1 However, advanced stage tumors are not effectively eradicated by MTD owing to suboptimal drug targeting, onset of therapeutic resistance and neoangiogenes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2fd6faa363acd94a84958d39000cbeff
https://doi.org/10.1158/1538-7445.sabcs16-p6-12-17

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Nanometronomic treatment of 4T1 breast cancer with nanocaged doxorubicin prevents drug resistance and circumvents cardiotoxicity

Autor: Luca Sorrentino, Fabio Corsi, Luisa Fiandra, Serena Mazzucchelli, Davide Prosperi, Manuela Nebuloni, Michela Bellini, Maria Antonietta Rizzuto, Marta Truffi, Erika Longhi

Publikováno v: Oncotarget

// Serena Mazzucchelli 1 , Michela Bellini 2 , Luisa Fiandra 1 , Marta Truffi 1 , Maria A. Rizzuto 2 , Luca Sorrentino 1 , Erika Longhi 1 , Manuela Nebuloni 1 , Davide Prosperi 2 , Fabio Corsi 1, 3 1 Department of Biomedical and Clinical Sciences “

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https://doi.org/10.18632/oncotarget.14204

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