Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michela Anna Polidoro"'
Autor:
Elisa Cauli, Michela Anna Polidoro, Simona Marzorati, Claudio Bernardi, Marco Rasponi, Ana Lleo
Publikováno v:
Journal of Biological Engineering, Vol 17, Iss 1, Pp 1-25 (2023)
Abstract The approval of anticancer therapeutic strategies is still slowed down by the lack of models able to faithfully reproduce in vivo cancer physiology. On one hand, the conventional in vitro models fail to recapitulate the organ and tissue stru
Externí odkaz:
https://doaj.org/article/206574081ba44015b2a57f6ffcd399f8
Autor:
Michela Anna Polidoro, Erika Ferrari, Cristiana Soldani, Barbara Franceschini, Giuseppe Saladino, Arianna Rosina, Andrea Mainardi, Francesca D’Autilia, Nicola Pugliese, Guido Costa, Matteo Donadon, Guido Torzilli, Simona Marzorati, Marco Rasponi, Ana Lleo
Publikováno v:
JHEP Reports, Vol 6, Iss 1, Pp 100910- (2024)
Background & Aims: Cholangiocarcinoma (CCA) is a primary liver tumour characterised by a poor prognosis and limited therapeutic options. Available 3D human CCA models fail to faithfully recapitulate the tumour niche. We aimed to develop an innovative
Externí odkaz:
https://doaj.org/article/5e864ded3a464d3da96a59ddc776a7f3
Autor:
Aurora Gazzillo, Camilla Volponi, Cristiana Soldani, Michela Anna Polidoro, Barbara Franceschini, Ana Lleo, Eduardo Bonavita, Matteo Donadon
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 26 (2023)
Liver cancer represents the fourth leading cause of cancer-associated death worldwide. The heterogeneity of its tumor microenvironment (TME) is a major contributing factor of metastasis, relapse, and drug resistance. Regrettably, late diagnosis makes
Externí odkaz:
https://doaj.org/article/96048340d86a4c5f9e56cebe65104a6f
Autor:
Aurora Gazzillo, Michela Anna Polidoro, Cristiana Soldani, Barbara Franceschini, Ana Lleo, Matteo Donadon
Publikováno v:
International journal of molecular sciences. 23(24)
The liver is the most common metastatic site in colorectal cancer (CRC) patients. Indeed, 25–30% of the cases develop colorectal liver metastasis (CLM), showing an extremely poor 5-year survival rate and resistance to conventional anticancer therap
Autor:
Matteo Donadon, Michela Anna Polidoro, Ana Lleo, Valentina Cazzetta, Domenico Mavilio, Joanna Mikulak, Guido Torzilli
Publikováno v:
World Journal of Gastroenterology
In the last years, several studies have been focused on elucidate the role of tumor microenvironment (TME) in cancer development and progression. Within TME, cells from adaptive and innate immune system are one of the main abundant components. The dy
Impact of RAS mutations on the immune infiltrate of colorectal liver metastases: A preliminary study
Autor:
Barbara Franceschini, Matteo Donadon, Flavio Milana, Luca Di Tommaso, Achille Anselmo, Federico Colombo, Sébastien Jaillon, Silvia Carnevale, Cristiana Soldani, Ana Lleo, Guido Torzilli, Matteo Cimino, Michela Anna Polidoro
Publikováno v:
Journal of Leukocyte Biology. 108:715-721
Kirsten rat sarcoma viral oncogene homolog KRAS proto-oncogene is the most common altered gene in colorectal cancer (CRC). Determining its mutational status, which is associated with worse prognosis and resistance to anti-epidermal growth factor rece
Autor:
Tiziana Feola, Felice Giangaspero, Angelis Michelangelo De, Valeria Palumbo, Vincenzo Esposito, Marie Lise Jaffrain-Rea, Roberta Morace, Antonietta Arcella, Michela Anna Polidoro, Francesca Gianno
Publikováno v:
Endocrine Abstracts.
Autor:
Guido Costa, Matteo Donadon, Faizan Nasir, Cristiana Soldani, Barbara Franceschini, Michela Anna Polidoro, Carlo Sposito, Matteo Virdis, Di Tommaso Luca, Andrea Vingiani, Vincenzo Mazzaferro, Guido Torzilli
Publikováno v:
Gastroenterology. 162:S-1324
Autor:
Flavio Milana, Matteo Donadon, Cristiana Soldani, Di Tommaso Luca, Barbara Franceschini, Martina Nebbia, Andrea Lania, Lleo De Nalda Ana, Michela Anna Polidoro, Guido Torzilli
Publikováno v:
Gastroenterology. 158:S-1548
Autor:
Roberta Morace, Adriano Angelucci, Antonietta Arcella, Liliya Rostomyan, Felice Giangaspero, Alessandro Colapietro, Luca Ventura, Michela Anna Polidoro, Vincenzo Esposito, Sandra Rotondi, Albert Beckers, Marie Lise Jaffrain-Rea
Publikováno v:
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 50(8)
Peroxisome proliferator-activated receptor alpha (PPARα) has been involved in the regulation of somatotroph tumour cells and may be targeted by different drugs, some of them are in current clinical use. The aim of this study was to investigate the e