Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Michela, Buccioni"'
Publikováno v:
Molecules, Vol 29, Iss 15, p 3501 (2024)
Cancer, a complex array of diseases, involves the unbridled proliferation and dissemination of aberrant cells in the body, forming tumors that can infiltrate neighboring tissues and metastasize to distant sites. With over 200 types, each cancer has u
Externí odkaz:
https://doaj.org/article/6a14d2ae430849b9a41df18cd4321e06
Autor:
Beatrice Francucci, Simone Angeloni, Diego Dal Ben, Catia Lambertucci, Massimo Ricciutelli, Andrea Spinaci, Aleksei Smirnov, Rosaria Volpini, Michela Buccioni, Gabriella Marucci
Publikováno v:
Molecules, Vol 28, Iss 12, p 4762 (2023)
Currently, the number of patients with neurodegenerative pathologies is estimated at over one million, with consequences also on the economic level. Several factors contribute to their development, including overexpression of A2A adenosine receptors
Externí odkaz:
https://doaj.org/article/0eb3a01762e042419555173ff01b8bcb
Autor:
Afraa Maiza, Franks Kamgang Nzekoue, Tesmine Ghazouani, Makrem Afif, Giovanni Caprioli, Dennis Fiorini, Sauro Vittori, Filippo Maggi, Michela Buccioni, Aleix Martì Navia, Gabriella Marucci, Sami Fattouch
Publikováno v:
Arabian Journal of Chemistry, Vol 13, Iss 12, Pp 8909-8919 (2020)
Ghee is a dairy product widely consumed in India, north-Africa, and Middle East countries, having beneficial pharmacological effects. This study aims to characterize the effects of aromatic plants addition (rosemary and clove) on the nutritional, vol
Externí odkaz:
https://doaj.org/article/d2117399942b4a50a07364f8a11eab32
Autor:
Claudia Sorbi, Silvia Franchini, Michela Buccioni, Antonio Cilia, Lorenza Pirona, Livio Brasili
Publikováno v:
Results in Chemistry, Vol 4, Iss , Pp 100425- (2022)
In the present work, nineteen analogues of 1-[(2,2-Diphenyl-1,3-dioxolan-4-yl)methyl]-4-(2-methoxyphenyl)piperazine 5 and N-[2-(2-Methoxyphenoxy)ethyl]-2,2-diphenyl-1,3-dioxolane-4-methanamine 18 were synthesized. The compounds were tested for bindin
Externí odkaz:
https://doaj.org/article/f777a42c520f4bb4b5fc5bc58cced3b8
Autor:
Andrea Spinaci, Michela Buccioni, Daniela Catarzi, Chang Cui, Vittoria Colotta, Diego Dal Ben, Eleonora Cescon, Beatrice Francucci, Ilenia Grieco, Catia Lambertucci, Gabriella Marucci, Davide Bassani, Matteo Pavan, Flavia Varano, Stephanie Federico, Giampiero Spalluto, Stefano Moro, Rosaria Volpini
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 167 (2023)
Based on a screening of a chemical library of A2A adenosine receptor (AR) antagonists, a series of di- and tri-substituted adenine derivatives were synthesized and tested for their ability to inhibit the activity of the enzyme casein kinase 1 delta (
Externí odkaz:
https://doaj.org/article/1f850dd815cb47c18c31a8c7ecb2492f
Autor:
Andrea Spinaci, Michela Buccioni, Diego Dal Ben, Gabriella Marucci, Rosaria Volpini, Catia Lambertucci
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/c67a43e4a702478cac46d3dbfebbf2bb
Autor:
Andrea Spinaci, Catia Lambertucci, Michela Buccioni, Diego Dal Ben, Claudia Graiff, Maria Cristina Barbalace, Silvana Hrelia, Cristina Angeloni, Seyed Khosrow Tayebati, Massimo Ubaldi, Alessio Masi, Karl-Norbert Klotz, Rosaria Volpini, Gabriella Marucci
Publikováno v:
Molecules, Vol 27, Iss 8, p 2386 (2022)
The A2A adenosine receptor (A2AAR) is one of the four subtypes activated by nucleoside adenosine, and the molecules able to selectively counteract its action are attractive tools for neurodegenerative disorders. In order to find novel A2AAR ligands,
Externí odkaz:
https://doaj.org/article/8f7e1f3a6a2f44a8853bfc137106b801
Autor:
Andrea Spinaci, Michela Buccioni, Diego Dal Ben, Federica Maggi, Gabriella Marucci, Beatrice Francucci, Giorgio Santoni, Catia Lambertucci, Rosaria Volpini
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 164 (2022)
The overexpression of the A3 adenosine receptor (AR) in a number of cancer cell types makes it an attractive target for tumor diagnosis and therapy. Hence, in the search for new A3AR ligands, a series of novel 2,N6-disubstituted adenosines (Ados) was
Externí odkaz:
https://doaj.org/article/3f4314c00fb541fa93a5e8daf41da736
Autor:
Flavia Varano, Daniela Catarzi, Erica Vigiani, Diego Dal Ben, Michela Buccioni, Gabriella Marucci, Lorenzo Di Cesare Mannelli, Elena Lucarini, Carla Ghelardini, Rosaria Volpini, Vittoria Colotta
Publikováno v:
Pharmaceuticals, Vol 14, Iss 7, p 657 (2021)
New compounds with a 7-amino-2-arylmethyl-thiazolo[5,4-d]pyrimidine structure were synthesized and evaluated in vitro for their affinity and/or potency at the human (h) A1, hA2A, hA2B, and hA3 adenosine receptors (ARs). Several compounds (5, 8–10,
Externí odkaz:
https://doaj.org/article/321d30349f8c4c519878eee1561c7b9f
Autor:
Afraa Maiza, Tesnime Ghazouani, Franks Kamgang Nzekoue, Giovanni Caprioli, Dennis Fiorini, Sauro Vittori, Beatrice Francucci, Gabriella Marucci, Michela Buccioni, Sami Fattouch
Publikováno v:
International Journal of Food Science & Technology. 57:7135-7142