Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Michel Veillard"'
Autor:
Joël Vacus, Christine Vauthier, and Michel Veillard, Stéphanie Desgouilles, J.L. Grossiord, Didier Bazile, Patrick Couvreur
Publikováno v:
Langmuir. 19:9504-9510
The preparation of nanoparticles by emulsion solvent evaporation is a very popular method. The purpose of the present study was to clarify the mechanism by which nanoparticles of ethylcellulose (EC) and poly(lactic acid) (PLA) are formed during the e
Traditionnellement, les normes financières internationales autorisent la comptabilisation des informations ayant un impact essentiellement financier. Le concept d'une comptabilité universelle plus responsabilisant relève un défi, celui de prendre
Publikováno v:
Journal of Controlled Release. 44:227-236
Prodan® release from poly(D,L-lactic acid) (PLA50) nanoparticles coated with albumin or polyvinyl alcohol (PVA) in simulated gastric and intestinal fluids (USP XXII) was investigated. Prodan® is a fluorescent marker, whose fluorescence properties e
Publikováno v:
Biomaterials. 17:715-723
Entirely biodegradable poly( d,l -lactic acid) (PLA 50 ) nanoparticles coated with albumin were prepared by the solvent evaporation technique. Their degradative properties were investigated in simulated gastric and intestinal fluids (USP XXII). The d
Autor:
Didier Bazile, Gilles Spenlehauer, Thierry Verrecchia, Denis Labarre, Francis Puisieux, Michaëlla Vittaz, Michel Veillard
Publikováno v:
Biomaterials. 17:1575-1581
The rapid uptake of injected nanoparticles by cells of the mononuclear phagocytes system (MPS) is a major obstacle when a long blood circulation time is needed. Whereas nanoparticles made from PLA and stabilized by surfactants (PLA-F68) are rapidly p
Publikováno v:
Drug Delivery. 3:187-195
Two oligopeptides with alternating hydrophilic-hydrophobic amino acids, H-(leu-lys-lys-leu)10-OH and H-(leu-lys-leu-lys)10-OH, were shown to have higher affinity for a 13-mer oligonucleotide than H-(pro-lys-lys-leu)10-OH used as a control. This incre
Autor:
Y. Archimbaud, Thierry Verrecchia, Didier Bazile, Michel Veillard, A. Murry-Brelier, Gilles Spenlehauer
Publikováno v:
Journal of Controlled Release. 36:49-61
Stealth liposomes and, today, stealth nanoparticles, constitute a new generation of parenteral therapeutic systems. PLA/ abumin nanoparticles are of particular interest because they constitute fully biodegradable and well tolerated colloidal suspensi
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 1:233-239
Because of their size ( dl -lactic acid) nanoparticles by a microfluidization and solvent evaporation process using the albumin as surfactant. After oral administration the radiolabel crosses the intestinal barrier and 17.8% of the radioactivity is r
Publikováno v:
International Journal of Pharmaceutics. 84:117-128
The combined effect of pH and vehicle composition on the buccal absorption of propranolol has been evaluated in vitro using hamster cheek pouch. Ethanol was used as cosolvent in various binary-water mixtures. Lauric acid, 1-menthol, sodium salicylate
Autor:
C. Ropert, M. Mariard, A. Frydman, Didier Bazile, Gilles Spenlehauer, Thierry Verrecchia, P. Huve, Michel Veillard
Publikováno v:
Biomaterials. 13:1093-1102
Fully biodegradable polylactic acid (PLA) nanoparticles (90–250 nm) coated with human serum albumin (HSA) were prepared by high-pressure emulsification and solvent evaporation, using the protein as surfactant. A new analytical tool was developed, b