Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michel V Levesque"'
Autor:
Eric Engelbrecht, Michel V Levesque, Liqun He, Michael Vanlandewijck, Anja Nitzsche, Hira Niazi, Andrew Kuo, Sasha A Singh, Masanori Aikawa, Kristina Holton, Richard L Proia, Mari Kono, William T Pu, Eric Camerer, Christer Betsholtz, Timothy Hla
Publikováno v:
eLife, Vol 9 (2020)
Despite the medical importance of G protein-coupled receptors (GPCRs), in vivo cellular heterogeneity of GPCR signaling and downstream transcriptional responses are not understood. We report the comprehensive characterization of transcriptomes (bulk
Externí odkaz:
https://doaj.org/article/2b95d8d5a479422885261efe96819fc7
Autor:
Michel V. Levesque, Timothy Hla
Publikováno v:
Cold Spring Harb Perspect Med
Extracellular signals act on G-protein-coupled receptors (GPCRs) to regulate homeostasis and adapt to stress. This involves rapid intracellular post-translational responses and long-lasting gene-expression changes that ultimately determine cellular p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5429e8a40d79d3515c94066400c61c
https://doi.org/10.1101/cshperspect.a041153
https://doi.org/10.1101/cshperspect.a041153
Autor:
Michel V. Levesque, Sasha A Singh, Michael Vanlandewijck, Timothy Hla, Anja Nitzsche, Eric Camerer, Kristina Holton, Masanori Aikawa, Andrew Kuo, William T. Pu, Christer Betsholtz, Eric Engelbrecht, Liqun He, Hira Niazi, Mari Kono, Richard L. Proia
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Despite the medical importance of G protein-coupled receptors (GPCRs), in vivo cellular heterogeneity of GPCR signaling and downstream transcriptional responses are not understood. We report the comprehensive characterization of transcriptomes (bulk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470a893386779f66b3962db8266921c6
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-407965
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-407965
Autor:
Eric Camerer, Anja Nitzsche, Kristina Holton, Michel V. Levesque, Masanori Aikawa, Andrew Kuo, Michael Vanlandewijck, Timothy Hla, Christer Betsholtz, Hira Niazi, Liqun He, Sasha A Singh, Mari Kono, Richard L. Proia, William T. Pu, Eric Engelbrecht
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d302ace29e2b3d7a2504f7c5954dbfc
https://doi.org/10.7554/elife.52690.sa2
https://doi.org/10.7554/elife.52690.sa2
Autor:
Michael Vanlandewijck, Timothy Hla, Kristina Holton, Sasha A Singh, Masanori Aikawa, Liqun He, Eric Camerer, Michel V. Levesque, Anja Nitzsche, Andrew Kuo, Mari Kono, Christer Betsholtz, Richard L. Proia, William T. Pu, Eric Engelbrecht
Despite the medical importance of G protein-coupled receptors (GPCRs), in vivo cellular heterogeneity of GPCR signaling and downstream transcriptional responses are not understood. We report the comprehensive characterization of transcriptomes (bulk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb00bbe99fcdaa8fc49ba590d8ff6a17
https://doi.org/10.1101/802892
https://doi.org/10.1101/802892
Autor:
Zhongjie Fu, Catherine H. Liu, Michel V. Levesque, Bongnam Jung, Steven L. Swendeman, Keisuke Yanagida, Timothy Hla, Kristina Holton, Andrew Kuo, Eric Engelbrecht, Colin Niaudet, Lois E.H. Smith, Konstantin Gaengel, Christer Betsholtz
Publikováno v:
Dev Cell
Transcriptional mechanisms that drive angiogenesis and organotypic vascular endothelial cell specialization are poorly understood. Here, we show that retinal endothelial sphingosine 1-phosphate receptors (S1PRs), which restrain vascular endothelial g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43025f8c03c70ea0a0d121845ba0505
https://doi.org/10.1016/j.devcel.2020.01.016
https://doi.org/10.1016/j.devcel.2020.01.016
Autor:
Robert J Scarborough, Michel V Lévesque, Etienne Boudrias-Dalle, Ian C Chute, Sylvanne M Daniels, Rodney J Ouellette, Jean-Pierre Perreault, Anne Gatignol
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 3, Iss C (2014)
Antisense-based molecules targeting HIV-1 RNA have the potential to be used as part of gene or drug therapy to treat HIV-1 infection. In this study, HIV-1 RNA was screened to identify more conserved and accessible target sites for ribozymes based on
Externí odkaz:
https://doaj.org/article/0d19bd4acfa544378dbcabd3f120b122
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9627 (2010)
For a long time nucleic acid-based approaches directed towards controlling the propagation of Hepatitis C Virus (HCV) have been considered to possess high potential. Towards this end, ribozymes (i.e. RNA enzymes) that specifically recognize and subse
Externí odkaz:
https://doaj.org/article/32defbadfebf44d29c990ac83b852d8e