Výsledky vyhledávání - "Michel Trumtel"

The Synthesis of Four Dideoxygenated Analogues of β-Maltosyl-(1→4)-Trehalose

Autor: Michel Trumtel, Rudolf E. Minder, Hans Peter Wessel

Publikováno v: Journal of Carbohydrate Chemistry. 17:1283-1306

Four derivatives of β-maltosyl-(1→4)-trehalose were prepared, each with two deoxy functions in one of the constitutive disaccharide building blocks. 2,3-Di-O-acetyl-4,6-dideoxy-4,6-diiodo-α-D-galactopyranosyl- (1→4) −1,2,3,6-tetra-O-acetyl-D-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb4338dd55eeeec2a084f26dac570755
https://doi.org/10.1080/07328309808001900

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The Synthesis of the 2′′- and 2′′′-Monodeoxygenated Analogues of β-Maltosyl-(1→4)-Trehalose

Autor: Michel Trumtel, Hans Peter Wessel

Publikováno v: Journal of Carbohydrate Chemistry. 16:1345-1361

Two derivatives of β-maltosyl-(1→4)-trehalose monodeoxygenated at C-2′′ or C-2′′′ have been synthesized in [2+2] block syntheses. O-(2,3,4,6-Tetra-O-benzyl-α-D-glucopyranosyl)-(1→4)-3,6-di-O-benzyl-1,2-di-O-acetyl-β-D-glucopyranose (

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https://doi.org/10.1080/07328309708005754

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Pivalates in the selective protection and activation of maltose for the synthesis of sulfated 3-deoxy-maltosyl-(1 → 4)-α,α-trehalose

Autor: Hans Peter Wessel, Michel Trumtel

Publikováno v: Carbohydrate Research. 297:163-168

Pivaloylation of maltose gave, in satisfactory yield, 1,2,6,2′,3′,4′,6′-hepta- O -pivaloyl-β-maltose which was converted to the 3-deoxygenated analogue in a Barton-McCombie reaction. This compound was used directly in a trimethylsilyl trifla

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https://doi.org/10.1016/s0008-6215(96)00262-5

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Selectively Deoxygenated Derivatives of β-Maltosyl-(1→4)-Trehalose as Biological Probes. II. the Synthesis of the 4- and 4′″-Monodeoxygenated Analogues

Autor: Marie-Claude Viaud, Hans Peter Wessel, Michel Trumtel

Publikováno v: Journal of Carbohydrate Chemistry. 15:769-786

Two derivatives of β-maltosyl-(1→4)-trehalose monodeoxygenated at positions 4 or 4′″ have been synthesized in [2+2] block syntheses. After the preparation of precursors with only one free hydroxyl group the deoxy function was introduced by a B

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https://doi.org/10.1080/07328309608005691

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Selectively Deoxygenated Derivatives of β-Maltosyl-(1→4)-Trehalose as Biological Probes

Autor: Hans Peter Wessel, Rudolf E. Minder, Michel Trumtel

Publikováno v: Journal of Carbohydrate Chemistry. 15:523-548

The four derivatives of β-maltosyl-(1→4)-trehalose have been synthesized, which are monodeoxygenated at the site of one of the primary hydroxyl groups. The tetrasaccharides were constructed in [2+2] block syntheses. Thus, 6′″-deoxy-β-maltosyl

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https://doi.org/10.1080/07328309608005672

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Selectively deoxygenated sulfated tetrasaccharides as probes for the investigation of smooth muscle cell antiproliferative activity

Autor: Niggi Iberg, Michel Trumtel, Hans Peter Wessel, Marie-Claude Viaud

Publikováno v: ResearcherID

Selectively deoxygenated analogues of highly (ca. 80 %) sulfated β-maltosyl-(1→4)-α,α-trehalose were investigated to map the importance of the individual sulfates for biological activity. Single deoxygenations led to activity losses up to 30 %;

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https://doi.org/10.1016/0960-894x(95)00554-7

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The heparin-like antiproliferative activity of sulfated tetrasaccharides is sensitive to structural variation

Autor: Hans Peter Wessel, Niggi Iberg, Eric Vieira, Thomas B. Tschopp, Michel Trumtel

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 5:437-442

The sulfated tetrasaccharide β-maltosyl-(1→4)-α,α-trehalose 2 with high antiproliferative activity on smooth muscle cells was modified in the maltosyl moiety by linking eight different disaccharides equatorially to trehalose; the biological acti

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https://doi.org/10.1016/0960-894x(95)00051-t

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ChemInform Abstract: Triflic Anhydride: An Alternative Promoter in Glycosidations

Autor: Hans Peter Wessel, Michel Trumtel, Alicia Dobarro-Rodriguez

Publikováno v: ChemInform. 23

The activation of glucosyl halides, trichloroacetimidates and of thioglucosides with triflic anhydride has been investigated showing that triflic anhydride promotes glycos idations with trichloracetimidates as well as with fluorides. There is also so

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https://doi.org/10.1002/chin.199229264

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