Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Michel Therisod"'
Autor:
Maciej Dabrowski, Michel Therisod, Racha Daher, Laurent Salmon, Stéphanie Courtiol-Legourd, Stéphanie Desvergnes
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:1511-1520
In the design of inhibitors of phosphosugar metabolizing enzymes and receptors with therapeutic interest, malonate has been reported in a number of cases as a good and hydrolytically-stable surrogate of the phosphate group, since both functions are d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180a05d78c222e030674b75060955e90
https://doi.org/10.1016/j.bmc.2011.12.050
https://doi.org/10.1016/j.bmc.2011.12.050
Autor:
Matthieu Fonvielle, Mary Jackson, Michel Therisod, Petra Gest, Racha Daher, Mathieu Coinçon, Marcelo E. Guerin, Jurgen Sygusch
Publikováno v:
Journal of Medicinal Chemistry. 53:7836-7842
We report the synthesis and biochemical evaluation of several selective inhibitors of class II (zinc dependent) fructose bis-phosphate aldolases (Fba). The products were designed as transition-state analogues of the catalyzed reaction, structurally r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5166c299aa983efa7bf7dd7d99d4700b
https://doi.org/10.1021/jm1009814
https://doi.org/10.1021/jm1009814
Publikováno v:
Biotechnology Progress. 20:1868-1871
Degradation of 2,6-dichlorophenol (2,6-DCP) was accomplished by oxidation catalyzed by Coprinus cinereus peroxidase. Immobilization of the enzyme in a polyacrylamide matrix enhanced DCP oxidation. Hydrogen peroxide, peroxidase's natural substrate, wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::161d1e91725f829a34412ceb6d78dac9
https://doi.org/10.1021/bp049750t
https://doi.org/10.1021/bp049750t
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 31:97-101
The oxidation of phenylalanine to benzaldehyde was performed in vitro by a bi-enzymatic system d -amino acid oxidase-peroxidase. We describe attempts to optimise experimental conditions and we propose a probable mechanism for the transformation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a59d4bbf4d453a459024ef83a955ec02
https://doi.org/10.1016/j.molcatb.2004.07.011
https://doi.org/10.1016/j.molcatb.2004.07.011
Publikováno v:
Tetrahedron: Asymmetry. 14:2487-2490
The possibility of the application of oxidase and peroxidase as catalysts in ionic liquids is demonstrated in the chemo- and stereoselective oxidation of sulfides. The high operational stability of these enzymes in ionic liquids is reported. The subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45ebf58c6fa22e371aec9bd9886c3fc9
https://doi.org/10.1016/s0957-4166(03)00578-0
https://doi.org/10.1016/s0957-4166(03)00578-0
Publikováno v:
Tetrahedron: Asymmetry. 13:519-522
We have devised a new bienzymatic oxidase–peroxidase system in which hydrogen peroxide is produced from air by a d -amino acid oxidase. The generated hydrogen peroxide is instantly used for asymmetric oxygenation of sulphides by a peroxidase. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5305339f5d0a53e3bedf8774cf1fcdc8
https://doi.org/10.1016/s0957-4166(02)00142-8
https://doi.org/10.1016/s0957-4166(02)00142-8
Publikováno v:
Inorganic Chemistry
Inorganic Chemistry, American Chemical Society, 2008, 47 ((7)), pp.2243-2245
Inorganic Chemistry, American Chemical Society, 2008, 47 ((7)), pp.2243-2245
A pair of novel C3-epimeric sugar-derived ligands (glycoligands) with a neutral N4O donor set was synthesized. Copper(II) complexes of both ligands were obtained and characterized by X-ray crystallography. Cyclic voltammetry, electron paramagnetic re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb922922ba4cb06d51814057c899ed0d
https://doi.org/10.1021/ic702209g
https://doi.org/10.1021/ic702209g
Publikováno v:
Tetrahedron: Asymmetry. 16:2681-2683
Several chiral heteroaryl-methyl-sulfoxides were prepared from the corresponding sulfides by an oxidation process catalysed by an oxidase/peroxidase bienzymatic system.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed762c491b6cf3b9929f72535ddaf8d7
https://doi.org/10.1016/j.tetasy.2005.07.004
https://doi.org/10.1016/j.tetasy.2005.07.004
Publikováno v:
Carbohydrate Research. 340:139-141
D-glucosaminic acid (2-amino-2-deoxy-D-gluconic acid), a component of bacterial lipopolysaccharides and a chiral synthon, is easily prepared on a multigram scale by air oxidation of D-glucosamine (2-amino-2-deoxy-D-glucose) catalysed by glucose oxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ab174ccdbeffcdd51b165c92d3bace
https://doi.org/10.1016/j.carres.2004.10.013
https://doi.org/10.1016/j.carres.2004.10.013
Publikováno v:
Tetrahedron Letters. 44:9047-9049
We report a new facile and efficient preparation of phosphoglycolohydroxamic acid, a known potent inhibitor of several enzymes acting on dihydroxyacetone phosphate. Phosphoglycolamide and phosphoglycolohydrazide can be obtained by the same method.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e03c302be9894c688bdb251b24df626a
https://doi.org/10.1016/j.tetlet.2003.09.210
https://doi.org/10.1016/j.tetlet.2003.09.210