Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Michel Pieren"'
Autor:
Axel B. Janssen, Vincent de Bakker, Rieza Aprianto, Vincent Trebosc, Christian Kemmer, Michel Pieren, Jan-Willem Veening
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Bacteria must adapt to the stresses of specific environmental conditions to survive. This adaptation is often achieved by altering gene expression through two-component regulatory systems (TCSs). In Gram-negative bacteria, the response to en
Externí odkaz:
https://doaj.org/article/d2e736e5d5a64d4f9481108b5ba0e830
Autor:
Vincent Trebosc, Valentina Lucchini, Mohit Narwal, Basil Wicki, Sarah Gartenmann, Birgit Schellhorn, Julian Schill, Marilyne Bourotte, Daniel Frey, Jürgen Grünberg, Andrej Trauner, Livia Ferrari, Antonio Felici, Olivia L. Champion, Marc Gitzinger, Sergio Lociuro, Richard A. Kammerer, Christian Kemmer, Michel Pieren
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 1868-1883 (2022)
The development of anti-virulence drug therapy against Acinetobacter baumannii infections would provide an alternative to traditional antibacterial therapy that are increasingly failing. Here, we demonstrate that the OmpR transcriptional regulator pl
Externí odkaz:
https://doaj.org/article/15918578828b477baf8ad5a55dd06209
Autor:
Valentina Lucchini, Adeline Sivignon, Michel Pieren, Marc Gitzinger, Sergio Lociuro, Nicolas Barnich, Christian Kemmer, Vincent Trebosc
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Gut microbiota dysbiosis toward adherent-invasive Escherichia coli (AIEC) plays an important role in Crohn’s disease (CD). The OmpR transcriptional regulator is required for the AIEC LF82 prototype strain to adhere and invade intestinal epithelial
Externí odkaz:
https://doaj.org/article/03e663cc3e85469bb13c1b7603dad794
Autor:
Vincent Trebosc, Sarah Gartenmann, Marcus Tötzl, Valentina Lucchini, Birgit Schellhorn, Michel Pieren, Sergio Lociuro, Marc Gitzinger, Marcel Tigges, Dirk Bumann, Christian Kemmer
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Nosocomial infections with Acinetobacter baumannii are a global problem in intensive care units with high mortality rates. Increasing resistance to first- and second-line antibiotics has forced the use of colistin as last-resort treatment, a
Externí odkaz:
https://doaj.org/article/91810f005a4447e3bedcd876f3281f97
Autor:
Karol Al Ayed, Denise Zamarbide Losada, Nataliia V. Machushynets, Barbara Terlouw, Somayah S. Elsayed, Julian Schill, Vincent Trebosc, Michel Pieren, Marnix H. Medema, Gilles P. van Wezel, Nathaniel I. Martin
Publikováno v:
ACS Infectious Diseases 9 (2023) 4
ACS Infectious Diseases, 9(4), 739-748
ACS Infectious Diseases, 9(4), 739-748
The unabated rise of antibiotic resistance has raised the specter of a post-antibiotic era and underscored the importance of developing new classes of antibiotics. The relacidines are a recently discovered group of nonribosomal lipopeptide antibiotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8b1f8dc30b226e87fcbcb3a89f3277
https://doi.org/10.1021/acsinfecdis.3c00043
https://doi.org/10.1021/acsinfecdis.3c00043
Autor:
Marcel Tigges, Birgit Schellhorn, Marc Gitzinger, Sarah Gartenmann, Vincent Trebosc, Marcus Tötzl, Michel Pieren, Dirk Bumann, Christian Kemmer, Valentina Lucchini, Sergio Lociuro
Publikováno v:
mBio, Vol 10, Iss 4, p e01083-19 (2019)
mBio
mBio, Vol 10, Iss 4 (2019)
mBio
mBio, Vol 10, Iss 4 (2019)
The discovery of antibiotics revolutionized modern medicine and enabled us to cure previously deadly bacterial infections. However, a progressive increase in antibiotic resistance rates is a major and global threat for our health care system. Colisti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b056f0f0d628e9fc9fc36c7728a66a1b
https://doaj.org/article/3a08648b46564891935b3c4f6f9cf1ce
https://doaj.org/article/3a08648b46564891935b3c4f6f9cf1ce
Autor:
Jasmin Schillinger, Elsa Sanchez-Garcia, Jörg Steinmann, Birgit Schellhorn, Uwe Koch, Markus Kaiser, Jens Bongard, Anna Laura Schmitz, Kenny Bravo-Rodriguez, Michael Ehrmann, Alexander Wolf, Gunther Zischinsky, Michel Pieren, Peter Nussbaumer, Jan Buer, Bert Klebl
Publikováno v:
ChemMedChem. 14(11)
Despite the availability of hundreds of antibiotic drugs, infectious diseases continue to remain one of the most notorious health issues. In addition, the disparity between the spread of multidrug-resistant pathogens and the development of novel clas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d9db6eabaf1e56176fbbaf4b003aa1
https://pubmed.ncbi.nlm.nih.gov/30945468
https://pubmed.ncbi.nlm.nih.gov/30945468
Autor:
S. Cébe Suarez, S. Arn, U. Hoffmann, J. Wood, C. Manlius, A. Bogucki, Michel Pieren, Kurt Ballmer-Hofer, L. Cariolato
The development of functional blood and lymphatic vessels requires spatio-temporal coordination of the production and release of growth factors such as vascular endothelial growth factors (VEGFs). VEGF family proteins are produced in multiple isoform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf4d3aaef115b097521aa02daffd9e3
http://doc.rero.ch/record/309822/files/18_2006_Article_6254.pdf
http://doc.rero.ch/record/309822/files/18_2006_Article_6254.pdf
Publikováno v:
Journal of Biological Chemistry
Europe PubMed Central
Europe PubMed Central
Membrane fusion is induced by SNARE complexes that are anchored in both fusion partners. SNAREs zipper up from the N to C terminus bringing the two membranes into close apposition. Their transmembrane domains (TMDs) might be mere anchoring devices, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9833bcc0702e2d4588a54576f0ed032d
Autor:
Birgit Schellhorn, Marcus Tötzl, Pablo Manfredi, Dirk Bumann, Vincent Trebosc, Marcel Tigges, Christian Kemmer, Michel Pieren, Sergio Lociuro, Peter C. Sennhenn, Kevin Royet, Sarah Gartenmann, Marc Gitzinger
Publikováno v:
Antimicrobial agents and chemotherapy. 60(12)
Infections with the Gram-negative coccobacillus Acinetobacter baumannii are a major threat in hospital settings. The progressing emergence of multidrug-resistant clinical strains significantly reduces the treatment options for clinicians to fight A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85da56d882fe437c7cd63cf8ae24a849
https://pubmed.ncbi.nlm.nih.gov/27671072
https://pubmed.ncbi.nlm.nih.gov/27671072