Zobrazeno 1 - 10
of 352
pro vyhledávání: '"Michel Paques"'
Autor:
Giacomo M. Bacci, Elisa Marziali, Sara Bargiacchi, Michel Paques, Gianni Virgili, Pina Fortunato, Marine Durand, Camilla Rocca, Angelica Pagliazzi, Viviana Palazzo, Lucia Tiberi, Debora Vergani, Samuela Landini, Angela Peron, Rosangela Artuso, Bianca Pacini, Monica Stabile, Andrea Sodi, Roberto Caputo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Aim of the present study is to evaluate the relationship between genetic and phenotypic data in a series of patients affected by grade I and II of foveal hypoplasia with stable fixation and good visual acuity using multimodal imaging techniq
Externí odkaz:
https://doaj.org/article/a46dacc4911b458c8c47605a52a68f87
Autor:
Marie Elise Wistrup Torm, Michael Pircher, Sophie Bonnin, Jesper Johannesen, Oliver Niels Klefter, Mathias Falck Schmidt, Jette Lautrup Frederiksen, Nicolas Lefaudeux, Jordi Andilla, Claudia Valdes, Pablo Loza-Alvarez, Luisa Sanchez Brea, Danilo Andrade De Jesus, Kate Grieve, Michel Paques, Michael Larsen, Kiyoko Gocho
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract This study tested if a high-resolution, multi-modal, multi-scale retinal imaging instrument can provide novel information about structural abnormalities in vivo. The study examined 11 patients with very mild to moderate non-proliferative dia
Externí odkaz:
https://doaj.org/article/676c9439b8bc439bab580766c1c33eea
Autor:
Bénédicte Dupas, Daniela Castro-Farias, Jean-François Girmens, Ali Eginay, Aude Couturier, Frederic Villeroy, Marie-Noëlle Delyfer, Catherine Creuzot-Garcher, Audrey Giocanti-Auregan, Laurence Béral, Carl Arndt, Charles Mesnard, Eric Vicaut, Philippe Chaumet-Riffaud, Isabelle Durand-Zaleski, Michel Paques
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Macular edema (ME) results from hyperpermeability of retinal vessels, leading to chronic extravasation of plasma components into the retina and hence potentially severe visual acuity loss. Current standard of care consists in usin
Externí odkaz:
https://doaj.org/article/0889a53fda7243a980f32b80e23b5e99
Autor:
Christophe Roubeix, Caroline Nous, Sébastien Augustin, Kaitryn E. Ronning, Thibaud Mathis, Frédéric Blond, Pauline Lagouge-Roussey, Sergio Crespo-Garcia, Patrick M. Sullivan, Emmanuel L. Gautier, Nadine Reichhart, José-Alain Sahel, Marie E. Burns, Michel Paques, Torben Lykke Sørensen, Olaf Strauss, Xavier Guillonneau, Cécile Delarasse, Florian Sennlaub
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Age-related macular degeneration (AMD) is invariably associated with the chronic accumulation of activated mononuclear phagocytes in the subretinal space. The mononuclear phagocytes are composed of microglial cells but also of monocyte-deriv
Externí odkaz:
https://doaj.org/article/15a2fe8398d24307833b4ae362a8cd9b
Autor:
Marie Darche, Ysé Borella, Anna Verschueren, Ivana Gantar, Stéphane Pagès, Laura Batti, Michel Paques
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-7 (2023)
Abstract We provide here a procedure enabling light sheet fluorescence microscopy (LSFM) of entire human eyes after iDISCO + -based clearing (ClearEye) and immunolabeling. Demonstrated here in four eyes, post-processing of LSFM stacks enables three-d
Externí odkaz:
https://doaj.org/article/904a0c3427094c27b8a851a715165422
Autor:
Alexandre Dentel, MD, Elena Brazhnikova, MD, Nathaniel Norberg, MSc, Céline Jaillard, PhD, Kate Grieve, PhD, Michel Paques, MD, PhD, José A. Sahel, MD, PhD, Stéphane Bertin, MD, Valérie Forster, MSc, Serge Picaud, PhD
Publikováno v:
Ophthalmology Science, Vol 3, Iss 4, Pp 100316- (2023)
Objective: To describe adaptive optics flood illumination ophthalmoscopy (AO-FIO) of the photoreceptor layer in normal nonhuman primates (NHPs) and in the case of a short-term induced retinal detachment (RD). Design: Longitudinal fundamental research
Externí odkaz:
https://doaj.org/article/bde445aa81b141f28d66182c94fe1d03
Autor:
Elena Gofas-Salas, Daniel M. W. Lee, Christophe Rondeau, Kate Grieve, Ethan A. Rossi, Michel Paques, Kiyoko Gocho
Publikováno v:
Diagnostics, Vol 14, Iss 7, p 768 (2024)
The Retinal Pigment Epithelium (RPE) plays a prominent role in diseases such as age-related macular degeneration, but imaging individual RPE cells is challenging due to their high absorption and low autofluorescence emission. The RPE lies beneath the
Externí odkaz:
https://doaj.org/article/c36ae76fe90a43a58493a8bc0c078ddc
Autor:
Sebastien Augustin, Marion Lam, Sophie Lavalette, Anna Verschueren, Frédéric Blond, Valérie Forster, Lauriane Przegralek, Zhiguo He, Daniel Lewandowski, Alexis-Pierre Bemelmans, Serge Picaud, José-Alain Sahel, Thibaud Mathis, Michel Paques, Gilles Thuret, Xavier Guillonneau, Cécile Delarasse, Florian Sennlaub
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Retinal melanosome/melanolipofuscin-containing cells (MCCs), clinically visible as hyperreflective foci (HRF) and a highly predictive imaging biomarker for the progression of age-related macular degeneration (AMD), are widely believed to be
Externí odkaz:
https://doaj.org/article/36478ff34584497caa06ecb1e684bdde
Autor:
Marie Darche, Anna Verschueren, Morgane Belle, Leyna Boucherit, Stéphane Fouquet, José Alain Sahel, Alain Chédotal, Ilaria Cascone, Michel Paques
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
An organic-solvent based clearing technique is used to visualize the vasculature in 3D using light sheet microscopy in retinal and hyaloid vessel development, and applied to branch retinal vein occlusion (BRVO) models.
Externí odkaz:
https://doaj.org/article/6c2a556e138a4d7b9b223cda3470cd5c
Autor:
Kassandra Groux, Anna Verschueren, Céline Nanteau, Marilou Clémençon, Mathias Fink, José-Alain Sahel, Claude Boccara, Michel Paques, Sacha Reichman, Kate Grieve
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Dynamic full-field optical coherence tomography (D-FFOCT) is used for live cell imaging of primary porcine retinal pigment epithelium (ppRPE) cultures and human induced pluripotent stem cell-derived RPE (hiRPE) cultures, allowing non-invasive realtim
Externí odkaz:
https://doaj.org/article/2d5649b8833b447b849efa3ccebc585d