Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Michel Pagès"'
Autor:
Priyanka Singh, Krishnananda Samanta, Ndeye Mathy Kebe, Grégory Michel, Baptiste Legrand, Vera E. Sitnikova, Andrey V. Kajava, Michel Pagès, Patrick Bastien, Christelle Pomares, Olivier Coux, Jean-François Hernandez
Publikováno v:
Bioorganic Chemistry
Bioorganic Chemistry, 2022, 119, pp.105539. ⟨10.1016/j.bioorg.2021.105539⟩
Bioorganic Chemistry, 2022, 119, pp.105539. ⟨10.1016/j.bioorg.2021.105539⟩
International audience; It is urgent to develop less toxic and more efficient treatments for leishmaniases and trypanosomiases. We explore the possibility to target the parasite mitochondrial HslVU protease, which is essential for growth and has no a
Autor:
Jean-Claude Dujardin, Pablo Prieto Barja, Victor Chaumeau, Yvon Sterkers, Heinz Himmelbauer, Gerald F. Späth, Pascale Pescher, Darek Kedra, Giovanni Bussotti, Michel Pagès, Franck Dumetz, Malgorzata A. Domagalska, Cedric Notredame, Hideo Imamura
Publikováno v:
Nature Ecology & Evolution
Nature Ecology & Evolution, Nature, 2017, 1 (12), pp.1961-1969. ⟨10.1038/s41559-017-0361-x⟩
Nature Ecology & Evolution, 2017, 1 (12), pp.1961-1969. ⟨10.1038/s41559-017-0361-x⟩
Nature Ecology & Evolution, Nature, 2017, 1 (12), pp.1961--1969. 〈10.1038/s41559-017-0361-x〉
Nature Ecology & Evolution, Nature, 2017, 1 (12), pp.1961-1969. ⟨10.1038/s41559-017-0361-x⟩
Nature Ecology & Evolution, 2017, 1 (12), pp.1961-1969. ⟨10.1038/s41559-017-0361-x⟩
Nature Ecology & Evolution, Nature, 2017, 1 (12), pp.1961--1969. 〈10.1038/s41559-017-0361-x〉
International audience; The parasite Leishmania~ donovani causes a fatal disease termed visceral leishmaniasis. The process through which the parasite adapts to environmental change remains largely unknown. Here we show that aneuploidy is integral fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae604ae550baa6edab92d03b257dabb7
https://hal-pasteur.archives-ouvertes.fr/pasteur-02107201
https://hal-pasteur.archives-ouvertes.fr/pasteur-02107201
Autor:
Lauriane Sollelis, Cameron Ross MacPherson, Yvon Sterkers, Artur Scherf, Patrick Bastien, Slavica Stanojcic, Michel Pagès, Frédéric Bringaud, Lucien Crobu, Maria-Rosa Garcia-Silva, Nada Kuk
Publikováno v:
EMBO Reports
EMBO Reports, EMBO Press, 2017, 18 (11), pp.1968-1977. ⟨10.15252/embr.201744216⟩
EMBO Reports, 2017, 18 (11), pp.1968-1977. ⟨10.15252/embr.201744216⟩
EMBO Reports, EMBO Press, 2017, 18 (11), pp.1968-1977. ⟨10.15252/embr.201744216⟩
EMBO Reports, 2017, 18 (11), pp.1968-1977. ⟨10.15252/embr.201744216⟩
International audience; Leishmania affects millions of people worldwide. Its genome undergoes constitutive mosaic aneuploidy, a type of genomic plasticity that may serve as an adaptive strategy to survive distinct host environments. We previously fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2edd50c144359ae35d3645bc70db8b
https://hal.archives-ouvertes.fr/hal-01745219
https://hal.archives-ouvertes.fr/hal-01745219
Autor:
Michel Pagès, Patrick Bastien, Carsten Janke, Magali Casanova, Juliette van Dijk, Frédérique de Monbrison
Publikováno v:
International Journal for Parasitology
International Journal for Parasitology, 2015, 45 (2-3), pp.121-132. ⟨10.1016/j.ijpara.2014.09.005⟩
International Journal for Parasitology, Elsevier, 2015, 45 (2-3), pp.121-132. ⟨10.1016/j.ijpara.2014.09.005⟩
International Journal for Parasitology, 2015, 45 (2-3), pp.121-132. ⟨10.1016/j.ijpara.2014.09.005⟩
International Journal for Parasitology, Elsevier, 2015, 45 (2-3), pp.121-132. ⟨10.1016/j.ijpara.2014.09.005⟩
International audience; Microtubules are subject to post-translational modifications, which are thought to have crucial roles in the function of complex microtubule-based organelles. Among these, polyglutamylation was relatively recently discovered,
Autor:
Lucien Crobu, Slavica Stanojcic, Patrick Bastien, Yvon Sterkers, Lauriane Sollelis, Michel Pagès, Etienne Schwob, Nada Kuk, Yves Balard
Publikováno v:
Scientific reports, vol 6, iss 1
Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6 (1), pp.23142. ⟨10.1038/srep23142⟩
Scientific Reports, 2016, 6 (1), pp.23142. ⟨10.1038/srep23142⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2016, 6 (1), pp.23142. ⟨10.1038/srep23142⟩
Scientific Reports, 2016, 6 (1), pp.23142. ⟨10.1038/srep23142⟩
Leishmania and Trypanosoma are unicellular parasites that possess markedly original biological features as compared to other eukaryotes. The Leishmania genome displays a constitutive ‘mosaic aneuploidy’, whereas in Trypanosoma brucei, the megabas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff96388a270d36676ff3a2af99a23909
https://escholarship.org/uc/item/6v33r3vw
https://escholarship.org/uc/item/6v33r3vw
Autor:
Laurence Lachaud, Patrick Bastien, Yvon Sterkers, Michel Pagès, Nathalie Bourgeois, Lucien Crobu
Publikováno v:
Molecular Microbiology. 86:15-23
Leishmania are unicellular eukaryotes that have many markedly original molecular features compared with other uni- or multicellular eukaryotes like yeasts or mammals. Genome plasticity in this parasite has been the subject of many publications, and h
Publikováno v:
Cellular Microbiology. 13:274-283
The protozoan parasite Leishmania is generally considered to be diploid, although a few chromosomes have been described as aneuploid. Using fluorescence in situ hybridization (FISH), we determined the number of homologous chromosomes per individual c
Publikováno v:
Genomics
Phytomonas spp. are members of the family Trypanosomatidae that parasitize plants and may cause lethal diseases in crops such as Coffee Phloem necrosis, Hartrot in coconut, and Marchitez sorpresiva in oil palm. In this study, the molecular karyotype
Autor:
Yvon Sterkers, Lucien Crobu, Patrick Bastien, Michel Pagès, Emmanuel Tetaud, Michèle Lefebvre, Diane-Ethna Mbang-Benet, Gilles Merlin, Corinne Blancard
Publikováno v:
Experimental Parasitology
Experimental Parasitology, Elsevier, 2016, 166, pp.97-107. ⟨10.1016/j.exppara.2016.04.004⟩
Experimental Parasitology, Elsevier, 2016, 166, pp.97-107. ⟨10.1016/j.exppara.2016.04.004⟩
International audience; TbFlabarin is the Trypanosoma brucei orthologue of the Leishmania flagellar protein LdFlabarin but its sequence is 33% shorter than LdFlabarin, as it lacks a C-terminal domain that is indispensable for LdFlabarin to localize t
Autor:
Nada Kuk, Christelle Morelle, Lucien Crobu, Michel Pagès, Diane-Ethna Mbang-Benet, Laurence Lachaud, Patrick Bastien, Yvon Sterkers, Pierre Portales
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2015, 43 (8), pp.4013-4027. ⟨10.1093/nar/gkv056⟩
Nucleic Acids Research, Oxford University Press, 2015, 43 (8), pp.4013-4027. ⟨10.1093/nar/gkv056⟩
Nucleic Acids Research, 2015, 43 (8), pp.4013-4027. ⟨10.1093/nar/gkv056⟩
Nucleic Acids Research, Oxford University Press, 2015, 43 (8), pp.4013-4027. ⟨10.1093/nar/gkv056⟩
International audience; Nucleoporins are evolutionary conserved proteins mainly involved in the constitution of the nuclear pores and trafficking between the nucleus and cytoplasm, but are also increasingly viewed as main actors in chromatin dynamics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fff8d14cab8920fd3b4c40e83347d4
https://hal.science/hal-01936574
https://hal.science/hal-01936574