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pro vyhledávání: '"Michel M. Sanders"'
Autor:
Dawne C. Dougherty, Michel M. Sanders
Publikováno v:
BioTechniques, Vol 39, Iss 2, Pp 203-207 (2005)
The ovalbumin gene (Ov) gene is responsive to estrogen, glucocorticoid, androgen, and progesterone. In our efforts to characterize the regulation of the Ov gene by steroid hormones, we have repeatedly observed that many vector backbones and promoters
Externí odkaz:
https://doaj.org/article/3b00cf51a3a647f48157ea98002123a5
Autor:
Bynthia M. Anose, Michel M. Sanders
Publikováno v:
International Journal of Endocrinology, Vol 2011 (2011)
The zinc finger E-box binding protein 1 (ZEB1) transcription factor belongs to a two-member family of zinc-finger homeodomain proteins involved in physiological and pathological events mostly relating to cell migration and epithelial to mesenchymal t
Externí odkaz:
https://doaj.org/article/aba030165af34c29841d32c861b8d9ad
Autor:
Eric C. Niederhoffer, Neil Osheroff, Michel M. Sanders, Karen Symes, Engelbert Buxbaum, Emine Ercikan Abali
Publikováno v:
Medical Science Educator. 24:349-351
Over the last decade, traditional discipline-based curricula in medical and dental education are being gradually replaced by integrated and/or organ-based curricula. Some medical schools have completed this transition while others are moving in this
Publikováno v:
Molecular and Cellular Biochemistry. 318:89-99
The zinc finger E-box binding transcription factor ZEB1 (deltaEF1/Nil-2-a/AREB6/zfhx1a/TCF8/zfhep/BZP) is emerging as an important regulator of the epithelial to mesenchymal transitions (EMT) required for development and cancer metastasis. ZEB1 promo
Publikováno v:
Biochimie. 88:1909-1914
The chicken ovalbumin (Ov) gene is one of the best models to study tissue-specific gene regulation because it is only expressed in the oviduct. In this paper, a tissue-specific element was characterized by 5'-flanking region deletion in combination w
Autor:
Michel M. Sanders, Dawne C. Dougherty
Publikováno v:
Trends in Endocrinology & Metabolism. 16:414-419
Despite decades of investigation, the molecular pathways triggered by estrogen that lead to tissue-specific cell proliferation, differentiation and survival are only superficially understood. If we are to modulate the actions of estrogen selectively
Transcriptional Activation by the Zinc-Finger Homeodomain ProteinδEF1 in Estrogen Signaling Cascades
Autor:
Michel M. Sanders, Naomi B. Dillner
Publikováno v:
DNA and Cell Biology. 23:25-34
The transcription factor delta EF1 is a key player in estrogen-signaling cascades in vertebrates. In this pathway, estrogen induces the expression of the gene encoding delta EF1, and then delta EF1 activates transcription of downstream targets. Yet,
Publikováno v:
Gene. 257:243-249
Although a number of genes have been identified whose transcriptional activities are stimulated by estrogen, relatively few have been discovered that are repressed. In an effort to determine whether estrogen can directly repress gene expression, atte
Publikováno v:
Molecular and Cellular Biology. 20:4626-4634
Interactions between estrogen and growth factor signaling pathways at the level of gene expression play important roles in the function of reproductive tissues. For example, estrogen regulates transforming growth factor beta (TGFbeta) in the uterus d
Publikováno v:
Molecular and Cellular Biology. 19:3600-3606
Estrogen acting via the estrogen receptor complex is responsible for the transcriptional regulation of many target genes in both reproductive and nonreproductive tissues. In fact, estrogen is being implicated in a growing number of human disease stat