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pro vyhledávání: '"Michel Leclerc"'
Autor:
Michel Leclerc
Publikováno v:
Archives of Immunology Research and Therapy. 1:01-03
In 1986, we have isolated (Delmotte et al, Eur J Immunol) an antibody-like factor composed of 4 subunits of 30 KDA each: It was an anti-TNP (TNP=Trinitrophényl) antibody-like substance)
Autor:
Michel Leclerc
Publikováno v:
Mathews Journal of Immunology & Allergy. 7
Autor:
Michel Leclerc
Publikováno v:
Mathews Journal of Immunology & Allergy. 6
Autor:
Michel Leclerc
Publikováno v:
International Journal of Research in Oncology. 1
The objective of this work is to assess whether recombinant protein SIP-Young-6 HIS, produced in HEK293, induces cell death in HeLa cells, when compared to doxorubicine action to achieve this, the metabolic activity is measured with the Cell Cytotoxi
Autor:
Michel Leclerc
Publikováno v:
Journal of Virology and Viral Diseases. 1
The sea star IGKappa gene was cloned in 2014 by the use of primers. It was compared in the present work to Marthasterias glacialis sea star genome. A high identity was found with this last one.
Autor:
Michel Leclerc
Publikováno v:
Journal of Virology and Viral Diseases. 1
The axial organ is considered as ancestral lymphoïd organ. It contains T and B sea star lymphocytes and Phagocytes. It plays a fundamental rôle in the sea star cell-mediated immune responses and humoral immune ones.Asterids belong to Echinoderma (I
Autor:
Michel Leclerc
Publikováno v:
Journal of Virology and Viral Diseases. 1
We attempt to establish, in the present paper, comparisons between 3 classes of Echinodermata (Asterids, Ophuirids, Crinoïds) out of 5 classes, at the level of genomes. Mainly we compare the IGKappa genes of these 3 classes which belong to Invertebr
Autor:
Michel Leclerc
Publikováno v:
Journal of Clinical Veterinary Research. 2:1-2
Some years ago, we found that Axial organ (AO) cells exerted an induced and spontaneous cytotoxicity against SP2 and MBL2 mouse tumoral cells. Recently, we discovered a sea star Igkappa gene with immune properties. This gene was first, inserted in a
Autor:
Michel Leclerc, Loïc Baerlocher
Publikováno v:
European Journal of Biology and Biotechnology. 2:60-62
MHC genes have been discovered in Echinodermata (Invertebrates containing 5 classes).2 classes (Ophuirids, Crinoïds) out of 5 possess HLA E, HLA B (Class I), HLADRB1, HLADQB1 (Class II). By the use of Mapping we identified 2 other MHC genes (Class I
Autor:
Michel Leclerc
Publikováno v:
Journal of Virology and Viral Diseases. 2:1-2
We have isolated recently MHC genes in Echinodermata [1] in 3 classes: The Ophuirids, the Crinoïds, the Asterids. At that time, we decided to synthetize one of these genes: The well-known HLA-E one in a PUC-GW-KAN plasmid (Yan Li gift).