Výsledky vyhledávání - "Michel Lacaille"

Intra-abdominal adipose depot variation in adipogenesis, lipogenesis, angiogenesis, and fibrosis gene expression and relationships with insulin resistance and inflammation in premenopausal women with severe obesity

Autor: Andrée-Anne Clément, Michel Lacaille, Mohamed Amine Lounis, Laurent D. Biertho, Denis Richard, Isabelle Lemieux, Jean Bergeron, Catherine Mounier, Denis R. Joanisse, Pascale Mauriège

Publikováno v: Journal of Physiology and Biochemistry. 78:527-542

Although severe obesity is associated with insulin resistance (IR) and inflammation, secretory function of intra-abdominal adipose tissues and their relationships with IR and inflammation markers remain poorly understood. Aims were to measure gene ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d9b2c222f5dcf3a2c90b0192e65c7b
https://doi.org/10.1007/s13105-021-00855-4

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High ApoD protein level in the round ligament fat depot of severely obese women is associated with an improved inflammatory profile

Autor: Denis R. Joanisse, Pascale Mauriège, Catherine Mounier, Frederik Desmarais, Jean Bergeron, Eric Rassart, Simon Biron, Karl-F. Bergeron, Michel Lacaille, Isabelle Lemieux

Publikováno v: Endocrine. 61:248-257

Apolipoprotein D (ApoD) is a lipocalin participating in lipid transport. It binds to a variety of ligands, with a higher affinity for arachidonic acid, and is thought to have a diverse array of functions. We investigated a potential role for ApoD in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e8786acaa1763b1522fd18b35bce105
https://doi.org/10.1007/s12020-018-1621-5

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Fitness, adiposopathy, and adiposity are independent predictors of insulin sensitivity in middle-aged men without diabetes

Autor: S. John Weisnagel, Pascale Mauriège, Hélène Arguin, Érick Couillard, Marie-Julie Dubois, Angelo Tremblay, Michel Lacaille, Claire Huth, Josée St-Onge, Denis R. Joanisse, Étienne Pigeon, André Marette, Marie-Ève Riou

Publikováno v: Journal of Physiology and Biochemistry. 72:435-444

Adiposopathy, or sick fat, refers to adipose tissue dysfunction that can lead to several complications such as dyslipidemia, insulin resistance, and hyperglycemia. The relative contribution of adiposopathy in predicting insulin resistance remains unc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::836e212ea0e19f65a87b23fb79aa86b7
https://doi.org/10.1007/s13105-016-0488-2

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The relationship between adiposopathy and glucose-insulin homeostasis is not affected by moderate-intensity aerobic training in healthy women with obesity

Autor: Sébastien Tessier, Francine Pérusse, Pascale Mauriège, Jean Doré, Mélanie Côté, John Weisnagel, Eléonor Riesco, Andrée-Anne Clément, Michel Lacaille, Denis R. Joanisse, Jean-Pierre Després

Publikováno v: Journal of physiology and biochemistry. 74(4)

The contribution of adiposopathy to glucose-insulin homeostasis remains unclear. This longitudinal study examined the potential relationship between the adiponectin/leptin ratio (A/L, a marker of adiposopathy) and insulin resistance (IR: homeostasis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85defe2b7ffa0cca1f898469453b42aa
https://pubmed.ncbi.nlm.nih.gov/29696568

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Chronic effects of dehydroepiandrosterone on rat adipose tissue metabolism

Autor: Pascale Mauriège, Céline Martel, Fernand Labrie, Yves Deshaies, Alain Bélanger, Michel Lacaille, Dominique Langin, Jean-Pierre Després

Publikováno v: Metabolism. 52:264-272

The goal of the present study was to examine cellular mechanisms that regulate adipose cell metabolism in ovariectomized (OVX) and intact rats that were subjected to long-term (27 weeks) treatment with dehydroepiandrosterone (DHEA). Forty-eight 16-mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2c9238fa026e5a91a403df39715d86
https://doi.org/10.1053/meta.2003.50043

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Irisin is more strongly predicted by muscle oxidative potential than adiposity in non-diabetic men

Autor: S. John Weisnagel, Claire Huth, Michel Lacaille, Angelo Tremblay, Denis R. Joanisse, Marie Julie Dubois, André Marette, Pascale Mauriège

Publikováno v: Journal of physiology and biochemistry. 71(3)

Numerous controversies surround the peptide hormone irisin. Although implicated as a myokine promoting the browning of adipose tissue in rodents, its roles in humans remain unclear. Contradictory results have also been found with respect to the relat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab453fc445600f0e4ea261938fc0c99f
https://pubmed.ncbi.nlm.nih.gov/25820475

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Plasma irisin is associated with insulin resistance in men (854.4)

Autor: Pascale Mauriège, Denis R. Joanisse, S. John Weisnagel, Claire Huth, Michel Lacaille, André Marette, Angelo Tremblay

Publikováno v: The FASEB Journal. 28

The hormone irisin has been described as increasing energy expenditure and improving glucose tolerance in mice, yet its potential role in humans remains controversial. Objective: We describe the association between circulating irisin and insulin resi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::084eca1b642f38e52a2a1b48bd93314e
https://doi.org/10.1096/fasebj.28.1_supplement.854.4

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Genomic scan for genes affecting body composition before and after training in Caucasians from HERITAGE

Autor: My Anh Ho-Kim, Jacques Gagnon, Arthur S. Leon, James S. Skinner, Louis Pérusse, D. C. Rao, Michel Lacaille, Treva Rice, Luigi Bouchard, Jack H. Wilmore, Claude Bouchard, Chantal Paré, Ingrid B. Borecki, Yvon C. Chagnon

Publikováno v: Journal of Applied Physiology. 90:1777-1787

An autosomal genomewide search for genes related to body composition and its changes after a 20-wk endurance-exercise training program has been completed in the HERITAGE Family Study. Phenotypes included body mass index (BMI), sum of eight skinfold t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8b32d92b24b624432a62ff821073c6
https://doi.org/10.1152/jappl.2001.90.5.1777

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A Genome-Wide Scan for Abdominal Fat Assessed by Computed Tomography in the Québec Family Study

Autor: D. C. Rao, Yvon C. Chagnon, Louis Pérusse, Treva Rice, Jean-Pierre Després, Claude Bouchard, Sonia Roy, Michael A. Province, Michel Lacaille, My-Ann Ho-Kim, Monique Chagnon, Simone Lemieux

Publikováno v: Scopus-Elsevier

To identify chromosomal regions harboring genes influencing the propensity to store fat in the abdominal area, a genome-wide scan for abdominal fat was performed in the Québec Family Study. Cross-sectional areas of the amount of abdominal total fat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6559b3bb883c9a1e314d0921c6dddbfe
https://doi.org/10.2337/diabetes.50.3.614

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Regional and gender variations in adipose tissue lipolysis in response to weight loss

Autor: Jean-Pierre Després, Pascale Mauriège, Natalie Alméras, Dominique Langin, Pascal Imbeault, Michel Lacaille, André J. Tremblay

Publikováno v: Journal of Lipid Research, Vol 40, Iss 9, Pp 1559-1571 (1999)
Europe PubMed Central

Catecholamine-induced lipolysis was investigated in 32 obese subjects (14 men and 18 premenopausal women), aged 36–50 years, whose body mass index ranged from 30 to 42 kg/m2. Isolated subcutaneous (subc) abdominal and femoral adipocytes were studie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40676cb9abaa29254440076170049e64
https://doi.org/10.1016/s0022-2275(20)33402-7

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