Výsledky vyhledávání - "Michel L. Hijmering"

Sympathetic activation markedly reduces endothelium-dependent, flow-mediated vasodilation

Autor: Michel L. Hijmering, Erik S.G. Stroes, Barbara A. Hutten, Jobien K. Olijhoek, Peter J. Blankestijn, Ton J. Rabelink

Publikováno v: Journal of the American College of Cardiology, 39(4), 683-688. Elsevier USA

OBJECTIVES We sought to evaluate whether increased sympathetic outflow may interfere with flow-mediated dilation (FMD). BACKGROUND Endothelial function, assessed as FMD, is frequently used as an intermediate end point in intervention studies. Many di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80db7c65cdc33d7833085587ab31633d
https://doi.org/10.1016/s0735-1097(01)01786-7

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Targeting cefuroxime plasma concentrations during coronary artery bypass graft surgery with cardiopulmonary bypass

Autor: Wobbe Hospes, Alexander J. Spanjersberg, Peter G. J. ter Horst, Marieke Aalbers, Michel L. Hijmering

Publikováno v: International journal of clinical pharmacy. 37(4)

Backgound Patients are at risk for severe postoperative infections after coronary artery bypass graft (CABG) surgery. Clinical laboratory data showed that unbound plasma concentrations of cefuroxime were not always adequate, therefore we developed a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9051090464e88c9c029b1e790822c78a
https://pubmed.ncbi.nlm.nih.gov/25791346

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Variability of flow mediated dilation: consequences for clinical application

Autor: Michel L. Hijmering, Erik S.G. Stroes, Gerard Pasterkamp, M. Sierevogel, Jan-Dirk Banga, Ton J. Rabelink

Publikováno v: Atherosclerosis. 157:369-373

Flow mediated vasodilatation (FMD), a non-invasive tool to assess endothelial function, has been shown to have prognostic value for the development of cardiovascular disease. Conventional B-mode ultrasonography has been criticised for its 'limited' r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee93452da519faaf1ae2b279b6785d09
https://doi.org/10.1016/s0021-9150(00)00748-6

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Selective ETA Receptor Antagonism with ABT-627 Attenuates All Renal Effects of Endothelin in Humans

Autor: Marina L. H. Honing, Ton J. Rabelink, Paul J. Morrison, Yonghong P. Yang, Robert J. Padley, David E. Ballard, Michel L. Hijmering

Publikováno v: Journal of the American Society of Nephrology. 11:1498-1504

Endothelin (ET-1) acts as a potent vasoconstrictor in the human kidney, and this vasoconstriction could contribute to the ischemia seen in acute renal failure. In animal studies, the vasoactive properties of ET-1 are known to be ET A receptor-and/or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e43e4f7fa8470658060a1cb7b7325a
https://doi.org/10.1681/asn.v1181498

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Effect of angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor antagonism on postprandial endothelial function

Autor: Ton J. Rabelink, Michel L. Hijmering, Hanneke W Wilmink, Erik S.G. Stroes, Willem D. Erkelens, Jan Dirk Banga

Publikováno v: Journal of the American College of Cardiology. 34(1):140-145

OBJECTIVES The purpose of this study was to determine whether endothelial dysfunction as a consequence of direct postprandial lipid response might be favorably influenced by angiotensin-converting enzyme inhibitors or angiotensin AT1 receptor antagon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6fbb415429509313d953d9bcba0c1ef

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Nitric Oxide Production Is Reduced in Patients With Chronic Renal Failure

Autor: Michel L. Hijmering, Peter Boer, Ron Wever, Hendrik A. Koomans, K Versluis, Ton J. Rabelink, van Hedderik Rijn, Fija M. Lagerwerf, Erik S.G. Stroes, Marianne C. Verhaar, J.J.P. Kastelein

Publikováno v: ResearcherID
Scopus-Elsevier

Abstract —In patients with chronic renal failure (CRF), atherosclerosis is a major cause of cardiovascular morbidity and mortality. Generally, atherosclerosis has been associated with a reduced bioavailability of nitric oxide (NO). Experimental stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19ce56eaa63a398a373ecbee9eb9185
https://doi.org/10.1161/01.atv.19.5.1168

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Origin of superoxide production by endothelial nitric oxide synthase

Autor: Robert Wever, Erik S.G. Stroes, M. A. M. J. van Zandvoort, E.E. van Faassen, Ton J. Rabelink, Michel L. Hijmering

Publikováno v: FEBS Letters. 438:161-164

Using fluorescence optical and electron spin resonance spectroscopy, we have investigated the production of superoxide by bovine endothelial nitric oxide synthase (NOS). In contrast to neuronal NOS, the heme moiety is identified as the exclusive sour

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a351f30d75912d866aec37397ed2a1
https://doi.org/10.1016/s0014-5793(98)01292-7

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Blood concentrations of cefuroxime in cardiopulmonary bypass surgery

Autor: Peter G. J. ter Horst, Wobbe Hospes, Alexander J. Spanjersberg, Bob Wilffert, Daphne Bertholee, Michel L. Hijmering

Publikováno v: International Journal of Clinical Pharmacy, 35(5), 798-804. SPRINGER

Objectives Patients with coronary artery bypass graft (CABG) surgery are at risk for severe postoperative infections. Prophylactic cefuroxime may help to reduce this risk, however sufficient concentrations, i.e. above the breakpoint (32 mg/L), are ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1a6337ce0444f6674e5f9bcb01fd0a
https://research.rug.nl/en/publications/da88a861-8fee-4462-a3ac-61cf83518624

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