Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Michel Kwong Tat Poon"'
Publikováno v:
Chinese Medicine. :103-108
This study aimed to explore a pharmacological activity marker for quality assurance of Dendrobium species. The immunopotentiating activity in aqueous extracts prepared from four Dendrobium species, including D. officinalis, was assessed by an in vitr
Autor:
Hoi Yan Leung, Po Yee Chiu, Michel Kwong Tat Poon, Na Chen, Kam Ming Ko, Eriol Pou Kwan Leong
Publikováno v:
BioFactors. 34:331-342
Mitochondrial decay is a major cause of aging, leading to the subsequent death of aerobic organisms including humans. In the present study, we examined the effects of supplementation with schisandrin B (Sch B, a dibenzocyclooctadiene derivative isola
Autor:
Tina T. X. Dong, Kam Ming Ko, Ada H.Y. Siu, Karl Wah Keung Tsim, Hoi Yan Leung, Michel Kwong Tat Poon, Po Yee Chiu
Publikováno v:
Planta Medica. 73:134-141
In order to investigate the biochemical mechanism of Dang-Gui Buxue Tang (DBT) involved in its cardioprotective action, the effects of DBT and related preparations on the cellular level of reduced glutathione (GSH) and on susceptibility to menadione-
Publikováno v:
Molecular and Cellular Biochemistry. 289:185-191
Effects of schisandrin B enantiomers ((+)Sch B and (-)Sch B) treatment on cellular reduced glutathione (GSH) level and heat shock protein (Hsp)25/70 production were investigated in H9c2 cardiomyocytes. (+)Sch B and (-)Sch B at 6.25 muM produced a tim
Publikováno v:
Life Sciences. 77:2887-2895
In order to explore the role of cytochrome P-450 (P-450) in schisandrin B (Sch B)-induced antioxidant and heat shock responses, the effect of 1-aminobenzotriazole (ABT, a broad spectrum inhibitor of P-450) on hepatic mitochondrial glutathione antioxi
Publikováno v:
Trends in Pharmacological Sciences. 25:3-6
The ‘Yin–Yang' theory is an ancient Chinese philosophy that underlies the practice of traditional Chinese medicine. Although Yang-tonic herbs tend to boost body function possibly through enhancing the mitochondrial oxidative processes, the Yin pr
Publikováno v:
Free Radical Biology and Medicine. 35:368-380
In this study, the time course of schisandrin B- (Sch B-) induced changes in hepatic mitochondrial glutathione antioxidant status (mtGAS) and heat shock protein (HSP) 25/70 induction was examined to study their differential roles in the hepatoprotect
Publikováno v:
Journal of Pharmacological Sciences. 93:501-504
In the present study, the hepatoprotective effect of metformin (Met), a dimethylbiguanide anti-hyperglycemic, was examined in a mouse model of liver damage induced by chronic repeated administration of carbon tetrachloride (CCl(4)) (5 microl/kg, twic
Publikováno v:
Pharmaceutical Biology. 40:298-301
Two enantiomers of schisandrin B (Sch B), an active ingredient isolated from the fruit of Schisandra chinensis, were chirally separated. Pretreating mice with (+)Sch B or (-)Sch B at a daily oral dose of 1 mmol/kg for 3 days protected against carbon
Publikováno v:
Pharmaceutical Biology. 36:189-193
The in vivo antioxidant mechanism of Sheng Mai San (SMS), a compound formulation in traditional Chinese medicine comprising Panax ginseng, Schisandra chinensis and Ophiopogon japonicus, was investigated using a rat model of CCl 4 hepatotoxicity. SMS-