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Combined immunoglobulin free light chains are novel predictors of cardiovascular events in patients with abdominal aortic aneurysm

Autor: Luis Miguel Blanco-Colio, C. Vegas-Dominguez, E. Nuñez, Michel Jb, J.L. Martin-Ventura, Jesús Vázquez, Carmen Gomez-Guerrero, L. Ortega-Villanueva, Jes S. Lindholt, I. Cerro-Pardo, R.R. Montero

Publikováno v: Cerro-Pardo, I, Lindholt, J S, Nunez, E, Montero, R R, Ortega-Villanueva, L, Vegas-Dominguez, C, Gomez-Guerrero, C, Michel, J B, Blanco-Colio, L M, Vazquez, J & Martin-Ventura, J L 2021, ' Combined immunoglobulin free light chains are novel predictors of cardiovascular events in patients with abdominal aortic aneurysm ', Atherosclerosis, vol. 331, pp. E244 . https://doi.org/10.1016/j.atherosclerosis.2021.06.750

Abdominal aortic aneurysm (AAA) is characterised by the presence of B cells and immunoglobulins in the aortic wall, mainly in the adventitia. Kappa (κ) and lambda (λ) free light chains (FLCs) are produced from B cells during immunoglobulin synthesi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41e94310c2e7a5d6c0a2eccc520b78e
https://portal.findresearcher.sdu.dk/da/publications/e0d01b72-52d5-464c-a4f0-7f867b4eda6e

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PCSK9 in the development of human atherosclerosis

Autor: C. Le Goff, Mathilde Varret, Youmna Ghaleb, Yara Azar, Catherine Deschildre, Isabelle Guillas, Catherine Boileau, M.-N. Lebel, M. Abi Fadel, Michel Jb, Yara Abou-Khalil, P. El Khoury, W. Le Goff, Sebastien Dupont, Sandy Elbitar

Publikováno v: Atherosclerosis. 331:e66

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39080740491512583f5c93e58fa9b083
https://doi.org/10.1016/j.atherosclerosis.2021.06.190

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P4485The number of lipoprotein(a) kringle IV-type 2 repeats is associated with the osteogenic profile of aortic valvular interstitial cells induced by plasma from patients with calcific aortic stenosis

Autor: Patrick Mathieu, Giuseppina Caligiuri, Mathilde Varret, N. Sayah, Catherine Deschildre, T S Simon, J. Laschet, Michel Jb, Anne Boutten, Dimitri Arangalage, L C L Cattan-Levy, B A Arsenault, David Messika-Zeitoun, Antonino Nicoletti, M C Croyal

Publikováno v: European Heart Journal. 40

Background Considerable progresses have been made in the invasive treatment of calcific aortic stenosis (AS), but there is still no pharmacological treatment available because the exact mechanism leading to the initiation of valvular calcification re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5eea2b3a0b82e0ba23de0e8b3bde0037
https://doi.org/10.1093/eurheartj/ehz745.0879

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Blood penetration into human aortic valves consecutive to endothelial micro-fissuring of the fibrosa determines the site of calcium deposition: Physiopathological implications

Autor: Fanny Perez, Marion Morvan, Dimitri Arangalage, Catherine Deschildre, David Messika-Zeitoun, Giuseppina Caligiuri, M.P. Jacob-Lenet, Christine Choqueux, G. Even, Antonino Nicoletti, L. Cattan-Levy, Michel Jb, Magnus Bäck, Isabelle Codogno, J. Laschet

Publikováno v: Archives of Cardiovascular Diseases Supplements. 11:106-107

Background Intraleaflet hematoma has been associated with advanced stages of aortic valve stenosis. Its presence is suspected to be involved in faster disease progression. However, the mechanism whereby the entry and the presence of blood elements in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d430677221c151b7b6171a14ac347a1
https://doi.org/10.1016/j.acvdsp.2018.10.234

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Expression of insulin receptor (IR) A and B isoforms, IGF-IR, and IR/IGF-IR hybrid receptors in vascular smooth muscle cells and their role in cell migration in atherosclerosis

Autor: Liliana Perdomo, Almudena Gómez-Hernández, Michel Jb, Sabela Díaz-Castroverde, Oscar Escribano, Jesús Egido, Nuria Beneit, Silvia Domínguez Fernández, José Luis Martín-Ventura, C. E. Fernández-García, Gema García-Gómez, Manuel Benito

Publikováno v: Cardiovascular Diabetology
Cardiovascular Diabetology, BioMed Central, 2016, 15 (1), pp.161. 〈10.1186/s12933-016-0477-3〉
Cardiovascular Diabetology, BioMed Central, 2016, 15 (1), pp.161. ⟨10.1186/s12933-016-0477-3⟩
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

Background Abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) is a major contributor to the development of atherosclerotic process. In a previous work, we demonstrated that the insulin receptor isoform A (IRA) and its associ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51637599b4912a88e1aeb9e19eb204fa
http://www.hal.inserm.fr/inserm-01407063/file/12933_2016_Article_477.pdf

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HDL and endothelial protection

Autor: Devy Diallo, Angélique Levoye, Olivier Meilhac, José Luis Martín-Ventura, L Maria Varela-Perez, Alexy Tran-Dinh, Michel Jb, Quoc Bao Dang, Bertrand Lapergue, Sandrine Delbosc, Elena Burillo

Publikováno v: British Journal of Pharmacology. 169:493-511

High-density lipoproteins (HDLs) represent a family of particles characterized by the presence of apolipoprotein A-I (apoA-I) and by their ability to transport cholesterol from peripheral tissues back to the liver. In addition to this function, HDLs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6663079110875df90ab6af84fd347d3
https://doi.org/10.1111/bph.12174

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