Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michel Homerin"'
Autor:
Kaïdre Bendjama, Alan Melcher, Samantha J. Turnbull, Fiona Collinson, Samantha Noutch, Karen Scott, Giles J. Toogood, Alan Anthoney, Chris Twelves, Michel Homerin, Emma West, Adel Samson, Jennifer Kingston, Christy Ralph, Nicolas Stojkowitz, Emma L. Tidswell, Michelle Johnpulle
Publikováno v:
Journal of Clinical Oncology. 36:3092-3092
3092Background: Oncolytic viruses (OV) constitute a promising modality of cancer therapy. Intra-tumoral administration has yielded encouraging clinical results, but restricted the use of OV to tumo...
Autor:
Charlotte Schmitt, Jean-Yves Delattre, Ludovic Nguyen Them, Philippe Erbs, Juliette Kempf, Hervé Chneiweiss, Ahmed Idbaih, Michel Homerin, Johann Foloppe
Publikováno v:
Journal of Clinical Oncology. 35:e13510-e13510
e13510 Background: Glioblastoma (GBM) is an incurable disease challenging innovations for significant therapeutic progress. TG6002 is a vaccinia virus that replicates mainly in tumor cells after deletion of genes coding for thymidine kinase and ribon
Autor:
Yee Chao, Riccardo Lencioni, François Habersetzer, Theresa Hickman, Jean-Marc Limacher, James F. Burke, Ari David Baron, Caroline J. Breitbach, Lara Longpre, David H. Kirn, Michel Homerin, Jeong Heo, Richard H. Patt, Monika Lusky, Derek J. Jonker
Publikováno v:
Journal of Clinical Oncology. 31:TPS4161-TPS4161
TPS4161^ Background: Pexa-Vec is a targeted oncolytic and immunotherapeutic vaccinia virus engineered to express human granulocyte-macrophage colony stimulating factor (GM-CSF). Direct oncolysis plus GM-CSF expression stimulates tumor vascular disrup
Autor:
Riccardo Lencioni, Michel Homerin, David H. Kirn, Caroline J. Breitbach, Richard H. Patt, Theresa Hickman, Jean-Marc Limacher, James M. Burke, Lara Longpre, Monika Lusky
Publikováno v:
Journal of Clinical Oncology. 30:TPS4152-TPS4152
TPS4152 Background: JX-594 is a first-in-class targeted oncolytic poxvirus designed to selectively replicate in and destroy cancer cells with epidermal growth factor receptor (EGFR)/ ras pathway activation. Direct oncolysis plus GM-CSF expression sti
Autor:
Céline Halluard, Clélia Orange, Philippe Erbs, Jean-Marc Limacher, Cécile Fournel-Frederico, Jean-Pierre Delord, Michel Homerin, F. Husseini, Jean-Emmanuel Kurtz, Chloé Jemming
Publikováno v:
Journal of Clinical Oncology. 30:2605-2605
2605 Background: TG4023 is a non-integrative and non-propagative Modified Vaccinia virus Ankara (MVA) expressing a chimeric yeast transgene (FCU1) coding for cytosine deaminase and uracil phosphoribosyl transferase that transform the pro-drug 5-flucy