Zobrazeno 1 - 10
of 253
pro vyhledávání: '"Michel H. J. Koch"'
Small-angle scattering of X-rays (SAXS) and neutrons (SANS) is an established method for the structural characterization of biological objects in a broad size range from individual macromolecules (proteins, nucleic acids, lipids) to large macromolecu
Autor:
Satoshi Fukuoka, Ulrich Zähringer, Thomas Gutsmann, Lena Heinbockel, Wilmar Correa, Klaus Brandenburg, Michel H. J. Koch
Publikováno v:
Journal of structural biology 194(1), 68-77 (2016). doi:10.1016/j.jsb.2016.01.014
Journal of structural biology 194(1), 68 - 77 (2016). doi:10.1016/j.jsb.2016.01.014
Lipopolysaccharides (LPS) belong to the strongest immune-modulating compounds known in nature, and are often described as pathogen-associated molecular patterns
Lipopolysaccharides (LPS) belong to the strongest immune-modulating compounds known in nature, and are often described as pathogen-associated molecular patterns
Autor:
Joonghan Kim, Jae Hyuk Lee, Michel H J Koch, Qingyu Kong, Hyotcherl Ihee, Michael Wulff, Kyung Hwan Kim
Publikováno v:
Journal of the American Chemical Society. 132:2600-2607
Ultrafast (ps) time-resolved X-ray scattering was used to study the structural dynamics of Ru(3)(CO)(12) in cyclohexane after photolysis at 260 nm. Two intermediates form after 100 ps at the onset of the reaction: Ru(3)(CO)(10) for the CO loss channe
Publikováno v:
Angewandte Chemie. 120:5632-5635
With the exception ofultrafastinfraredspectroscopy,whichhasbeenmostefficientin identifying intermediates based on the detection ofbridgingCOligands,mosttechniqueshavefailedtocharac-terize the structure of the intermediates. Recent ultrafastinfraredsp
Publikováno v:
The Protein Journal. 26:585-591
As a general rule protein concentration typical for structural studies differs considerably from that chosen for kinetic investigations. Consequently, structure-function relationships are often postulated without appropriate knowledge, whether the fu
Autor:
Michel H. J. Koch, Klaus Brandenburg, Karl-Heinz Wiesmüller, Günther Jung, Artur J. Ulmer, Manfred Rössle, Jörg Howe, Tobias Seyberth, Andra B. Schromm, Thomas Gutsmann
Publikováno v:
Journal of Biological Chemistry. 282:11030-11037
The importance of the biological function and activity of lipoproteins from the outer or cytoplasmic membranes of Gram-positive and Gram-negative bacteria is being increasingly recognized. It is well established that they are like the endotoxins (lip
Autor:
Jörg Howe, Klaus Brandenburg, Thomas Gutsmann, Maite Iriarte, Michel H. J. Koch, Patrick Garidel, Ignacio Moriyón, Jörg Andrä, Raquel Conde
Publikováno v:
Dadun. Depósito Académico Digital de la Universidad de Navarra
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Cationic antimicrobial cationic peptides (CAMP) have been found in recent years to play a decisive role in hosts’ defense against microbial infection. They have also been investigated as a new therapeutic tool, necessary in particular due to the in
Autor:
Ying-Huang Lai, Andre Gabriel, Hwo-Sheunn Sheu, Ming-Tao Lee, Ya-Sen Sun, Tsang-Lang Lin, Chia-Hung Hsu, Keng S. Liang, Michel H. J. Koch, Jhih-Min Lin, Yu-Shan Huang, Wei-Tsung Chuang, U-Ser Jeng, Hsin Yi Lee
Publikováno v:
Journal of Applied Crystallography. 39:871-877
A SWAXS (small- and wide-angle X-ray scattering) instrument was recently installed at the wiggler beamline BL17B3 of the National Synchrotron Radiation Research Center (NSRRC), Taiwan. The instrument, which is designed for studies of static and dynam
Publikováno v:
Journal of Heterocyclic Chemistry. 43:1261-1265
In the course of our search for compounds with potential antitumor properties we have undertaken the synthesis of benzo[c][1,8]phenanthroline derivatives. Our project required the preparation of 8,9-dimethoxy benzo[c][1,8]phenanthrolin-6-ones. This w
Publikováno v:
European Journal of Pharmaceutical Sciences. 27:44-53
The ultrastructure of aqueous colloidal dispersions of the cubic monoolein/poloxamer 407/water phase, in particular the particle size distribution and presence of an additional vesicular fraction, highly depends on composition and preparation paramet