EFA6B regulates a stop signal for collective invasion in breast cancer

Autor: Racha Fayad, Monserrat Vázquez Rojas, Mariagrazia Partisani, Pascal Finetti, Shiraz Dib, Sophie Abelanet, Virginie Virolle, Anne Farina, Olivier Cabaud, Marc Lopez, Daniel Birnbaum, François Bertucci, Michel Franco, Frédéric Luton

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)

Reduced expression of EFA6B is found in highly metastatic breast cancer subtypes. Here, the authors report that loss of EFA6B promotes collective invasion through activation of the epithelial-to-mesenchymal transition program and CDC42-dependent sign

Externí odkaz: https://doaj.org/article/0787bba0953b47b2823c7bc21ef9994c

Chlortetracycline, a Novel Arf Inhibitor That Decreases the Arf6-Dependent Invasive Properties of Breast Cancer Cells

Autor: Eric Macia, Monserrat Vazquez-Rojas, Alessia Robiolo, Racha Fayad, Sophie Abélanet, Isabelle Mus-Veteau, Fabien Fontaine-Vive, Mohamed Mehiri, Frédéric Luton, Michel Franco

Publikováno v: Molecules, Vol 26, Iss 4, p 969 (2021)

Breast cancer is a major disease for women worldwide, where mortality is associated with tumour cell dissemination to distant organs. While the number of efficient anticancer therapies increased in the past 20 years, treatments targeting the invasive

Externí odkaz: https://doaj.org/article/e4d3d005e5dc453380a0885aa347ff2e

A bacterial Ras-like small GTP-binding protein and its cognate GAP establish a dynamic spatial polarity axis to control directed motility.

Autor: Yong Zhang, Michel Franco, Adrien Ducret, Tâm Mignot

Publikováno v: PLoS Biology, Vol 8, Iss 7, p e1000430 (2010)

Regulated cell polarity is central to many cellular processes. We investigated the mechanisms that govern the rapid switching of cell polarity (reversals) during motility of the bacterium Myxococcus xanthus. Cellular reversals are mediated by pole-to

Externí odkaz: https://doaj.org/article/91a50681426d4e668a420f36ab854ada

Probabilistic Force Estimation and Event Localization (PFEEL) algorithm

Autor: Zhaoshuo Jiang, Jean Michel Franco, Yohanna MejiaCruz, Juan M. Caicedo

Publikováno v: Engineering structures. 252

Localization of human activity using floor vibrations has gained attention in recent years. In human health technologies, floor vibrations have been recently used to estimate gait parameters to predict a patients’ health status. Various methodologi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab47015037348da8e9116880d4340e47
https://pubmed.ncbi.nlm.nih.gov/35645429

EFA6B regulates a stop signal for collective invasion in breast cancer

Autor: Shiraz Dib, Mariagrazia Partisani, Pascal Finetti, Virginie Virolle, Anne Farina, Frédéric Luton, Marc Lopez, Michel Franco, Sophie Abelanet, Monserrat Vázquez Rojas, Olivier Cabaud, Racha Fayad, Daniel Birnbaum, François Bertucci

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12, pp.2198. ⟨10.1038/s41467-021-22522-4⟩
Nature Communications, 2021, 12, pp.2198. ⟨10.1038/s41467-021-22522-4⟩
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)

Cancer is initiated by somatic mutations in oncogenes or tumor suppressor genes. However, additional alterations provide selective advantages to the tumor cells to resist treatment and develop metastases. Their identification is of paramount importan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0472ce9944e8675ae9b1cd7dcf7bf89c
http://europepmc.org/articles/PMC8044243