Interplay between glutathione, Atx1 and copper: X-ray absorption spectroscopy determination of Cu(I) environment in an Atx1 dimer

Autor: Christophe Den Auwer, Michel Ferrand, Elisabeth Mintz, Serge Crouzy, Roger Miras, Clara Fillaux, David Poger, Pascale Delangle

Publikováno v: Journal of Biological Inorganic Chemistry
Journal of Biological Inorganic Chemistry, Springer Verlag, 2008, 13 (8), pp.1239-48. ⟨10.1007/s00775-008-0408-1⟩
Journal of Biological Inorganic Chemistry, 2008, 13 (8), pp.1239-48. ⟨10.1007/s00775-008-0408-1⟩

X-ray absorption techniques have been used to characterise the primary coordination sphere of Cu(I) bound to glutathionate (GS−), to Atx1 and in Cu 2 I (GS−)2(Atx1)2, a complex recently proposed as the major form of Atx1 in the cytosol. In each c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df2cb01d4b17620db3b065d8623484b3
https://doi.org/10.1007/s00775-008-0408-1

Neuroprotective Role of a Proline-Rich Akt Substrate in Apoptotic Neuronal Cell Death after Stroke: Relationships with Nerve Growth Factor

Autor: Purnima Narasimhan, Pak H. Chan, Michel Ferrand-Drake, Shuzo Okuno, Takeshi Hayashi, Atsushi Saito

Publikováno v: The Journal of Neuroscience. 24:1584-1593

The Akt signaling pathway contributes to regulation of apoptosis after a variety of cell death stimuli. A novel proline-rich Akt substrate (PRAS) was recently detected and found to be involved in apoptosis. In our study, Akt activation was modulated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a73bd8a4d216d300a78e7b23755d6fa
https://doi.org/10.1523/jneurosci.5209-03.2004

Overexpression of Copper/Zinc Superoxide Dismutase in Transgenic Mice Protects against Neuronal Cell Death after Transient Focal Ischemia by Blocking Activation of the Bad Cell Death Signaling Pathway

Autor: Takeshi Hayashi, Michel Ferrand-Drake, Atsushi Saito, Shuzo Okuno, Pak H. Chan

Publikováno v: The Journal of Neuroscience. 23:1710-1718

The Bad signaling pathway contributes to the regulation of apoptosis after a variety of cell death stimuli, and Bad plays a key role in determining cell death or survival. We have reported that overexpression of copper/zinc superoxide dismutase (SOD1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b69f985a8fcc7d6f7bd698acbf561d
https://doi.org/10.1523/jneurosci.23-05-01710.2003

Cell death in the choroid plexus following transient forebrain global ischemia in the rat

Autor: Michel Ferrand-Drake

Publikováno v: Microscopy Research and Technique. 52:130-136

Following a complete disruption of blood flow to the brain, cerebral ischemia, a specific neuronal population, namely the CA1 pyramidal neurons in the hippocampus, will die a delayed type of cell death. This is often referred to as “delayed neurona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb04841ac4ced8c4c27517c6d733c675
https://doi.org/10.1002/1097-0029(20010101)52:1<130::aid-jemt14>3.0.co

Dynamical transition and molecular motions in a channel-like inclusion compound under hydrostatic pressure

Autor: Michel Ferrand, N. D. Morelon, Jérôme Combet, M. Bée

Publikováno v: Physica B: Condensed Matter. 266:56-59

Tano molecules (C 9 H 16 NO 2 ) form channel-like inclusion compounds with a great variety of linear hydrocarbons. At room temperature, both tano and included chains are dynamically disordered. Tano molecules can adopt one of their two enantiomeric f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::999489dcd5355478e2e7e507596daadd
https://doi.org/10.1016/s0921-4526(98)01504-x