Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Michel Engeln"'
Autor:
Michel Engeln, Serge H. Ahmed, Caroline Vouillac, François Tison, Erwan Bezard, Pierre-Olivier Fernagut
Publikováno v:
Neurobiology of Disease, Vol 49, Iss , Pp 79-86 (2013)
Striatal D2 and D3 dopamine receptors are involved in mediating the reinforcing properties of natural rewards and drugs. In Parkinson's disease, while D2/3 dopamine agonists alleviate motor symptoms, behavioral addictions and withdrawal syndrome are
Externí odkaz:
https://doaj.org/article/f2c79dbe00db45cd8b639599d5d6db7f
Autor:
Megan E. Fox, Andreas B. Wulff, Daniela Franco, Eric Y. Choi, Cali A. Calarco, Michel Engeln, Makeda D. Turner, Ramesh Chandra, Victoria M. Rhodes, Scott M. Thompson, Seth A. Ament, Mary Kay Lobo
Publikováno v:
Biological Psychiatry. 93:489-501
Opioid discontinuation generates a withdrawal syndrome marked by increased negative affect. Increased symptoms of anxiety and dysphoria during opioid discontinuation are significant barriers to achieving long-term abstinence in opioid-dependent indiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9717ea1f02835272bee5a04ff210675
https://doi.org/10.1016/j.biopsych.2022.08.023
https://doi.org/10.1016/j.biopsych.2022.08.023
Autor:
Megan E. Fox, Andreas B. Wulff, Daniela Franco, Eric Choi, Cali A. Calarco, Michel Engeln, Makeda D. Turner, Ramesh Chandra, Victoria M. Rhodes, Scott M. Thompson, Seth A. Ament, Mary Kay Lobo
SummaryOpioid discontinuation generates a withdrawal syndrome marked by a negative emotional state. Increased anxiety and dysphoria during opioid discontinuation are a significant barrier to achieving long-term abstinence in opioid-dependent individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1fbc5c02ef06a8c0f5865f0659e2f5a
https://doi.org/10.1101/2022.05.15.491856
https://doi.org/10.1101/2022.05.15.491856
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: Stress exposure has a lasting impact on motivated behavior and can exacerbate existing vulnerabilities for developing a substance use disorder. Several models have been developed to examine how stressful experiences shape drug-reward. Thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951435688ee69f37435f8164ff3d9965
https://doi.org/10.1007/s00213-020-05657-y
https://doi.org/10.1007/s00213-020-05657-y
Autor:
Swarup Mitra, Ramesh Chandra, Michel Engeln, David M. Dietz, Megan E. Fox, Mary Kay Lobo, Utsav Gyawali
Publikováno v:
Biol Psychiatry
Background We previously showed that the transcription factor Egr3 (early growth response 3) is oppositely regulated in nucleus accumbens (NAc) cell subtypes 24 hours following cocaine exposure and bidirectionally mediates cocaine-related behaviors i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b0148af3fe3dcfc4eec80b295212cb
https://doi.org/10.1016/j.biopsych.2019.10.019
https://doi.org/10.1016/j.biopsych.2019.10.019
Autor:
T. Chase Francis, Ronna Hertzano, Makeda D. Turner, Mary Kay Lobo, Shavin Thomas, Ramesh Chandra, Ashley La, Megan E. Fox, Yang Song, Michel Engeln, Brianna Evans
Publikováno v:
Molecular psychiatry
Motor stereotypies occurring in early-onset neuropsychiatric diseases are associated with dysregulated basal ganglia direct-pathway activity. Disruptions in network connectivity through impaired neuronal structure have been implicated in both rodents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a09f724ea3051ce3f8ccfa12bdfa86
https://doi.org/10.1038/s41380-020-0746-0
https://doi.org/10.1038/s41380-020-0746-0
Autor:
Shana Golden, Ramesh Chandra, Yonatan M. Kupchik, Gal Elyasaf, Mary Kay Lobo, Nimrod Bernat, Michel Engeln, Hyungwoo Nam, Mahashweta Basu, Seth A. Ament, Tal Odesser, Rianne Campbell
The ventral pallidum (VP) is central to reward seeking and withdrawal from drugs of abuse. A characteristic of the VP is the diversity of its projection targets. Yet, it remains unknown whether different VP projections also differ in other aspects, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c18989391fcc9d0cfe81a4223f7aa43
https://doi.org/10.1101/2021.11.15.468637
https://doi.org/10.1101/2021.11.15.468637
Autor:
Rae J. Herman, Michel Engeln, Victoria M. Rhodes, Eric Y. Choi, Ramesh Chandra, Houman Qadir, Mary Kay Lobo, Makeda D. Turner, Megan E. Fox, Cali A. Calarco, Shavin Thomas, Hyungwoo Nam
Psychostimulant exposure alters the activity of ventral pallidum (VP) projection-neurons. However, the molecular underpinnings of these circuit dysfunctions are unclear. We used RNA- sequencing to reveal alterations in the transcriptional landscape o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1ef5979dced1c330f288a4a5053f11e
https://doi.org/10.1101/2021.10.20.465105
https://doi.org/10.1101/2021.10.20.465105
Autor:
Megan Fox, Andreas Wulff, Daniela Franco, Eric Choi, Michel Engeln, Cali Calarco, Makeda Turner, Ramesh Chandra, Scott Thompson, Seth A. Ament, Mary Kay Lobo
Publikováno v:
Biological Psychiatry. 91:S13-S14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b17b20b6f7fac9b11c443483f06a16ab
https://doi.org/10.1016/j.biopsych.2022.02.052
https://doi.org/10.1016/j.biopsych.2022.02.052
Autor:
Thomas A. Blanpied, Sarah R. Metzbower, Mary Kay Lobo, Ramesh Chandra, Michel Engeln, A Gaynor, Brianna Evans, Prasad Konkalmatt, T C Francis
Publikováno v:
Molecular Psychiatry. 22:1512-1519
Molecular and cellular adaptations in nucleus accumbens (NAc) medium spiny neurons (MSNs) underlie stress-induced depression-like behavior, but the molecular substrates mediating cellular plasticity and activity in MSN subtypes in stress susceptibili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf6f20d8574d7acc42b7591101471711
https://doi.org/10.1038/mp.2017.178
https://doi.org/10.1038/mp.2017.178