Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Michel Enamorado"'
1
Akademický článek
DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells
Autor: Ruth Conde-Garrosa, David Sancho, Santos Mañes, Alfonso R Sanchez-Paulete, Francisco J Cueto, Carlos del Fresno, Paola Brandi, Alexis J. Combes, Elena Hernández-García, Michel Enamorado, Christian P Bromley, Manuel J Gomez, Santiago Zelenay, Salvador Iborra, Matthew F. Krummel
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background Conventional type 1 dendritic cells (cDC1s) are central to antitumor immunity and their presence in the tumor microenvironment associates with improved outcomes in patients with cancer. DNGR-1 (CLEC9A) is a dead cell-sensing receptor highl
Externí odkaz: https://doaj.org/article/7174fcff49ec4c968e5c2cd9447b8742
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2
Akademický článek
Von Hippel-Lindau Protein Is Required for Optimal Alveolar Macrophage Terminal Differentiation, Self-Renewal, and Function
Autor: Helena M. Izquierdo, Paola Brandi, Manuel-José Gómez, Ruth Conde-Garrosa, Elena Priego, Michel Enamorado, Sarai Martínez-Cano, Iria Sánchez, Laura Conejero, Daniel Jimenez-Carretero, Silvia Martín-Puig, Martin Guilliams, David Sancho
Publikováno v: Cell Reports, Vol 24, Iss 7, Pp 1738-1746 (2018)
Summary: The rapid transit from hypoxia to normoxia in the lung that follows the first breath in newborn mice coincides with alveolar macrophage (AM) differentiation. However, whether sensing of oxygen affects AM maturation and function has not been
Externí odkaz: https://doaj.org/article/c9d11d4f274940618ebe34423d921468
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3
Akademický článek
Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells
Autor: Michel Enamorado, Salvador Iborra, Elena Priego, Francisco J. Cueto, Juan A. Quintana, Sarai Martínez-Cano, Ernesto Mejías-Pérez, Mariano Esteban, Ignacio Melero, Andrés Hidalgo, David Sancho
Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Circulating memory cells include central memory T cells retaining the ability to enter the lymph nodes whereas tissue resident memory cells are confined to the parenchymal tissues. Here the authors explore the interplay between the two T-cell types a
Externí odkaz: https://doaj.org/article/aa0049fe97b2432095bd04330e3dc366
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4
Akademický článek
Genealogy, Dendritic Cell Priming, and Differentiation of Tissue-Resident Memory CD8+ T Cells
Autor: Michel Enamorado, Sofía C. Khouili, Salvador Iborra, David Sancho
Publikováno v: Frontiers in Immunology, Vol 9 (2018)
Tissue-resident memory CD8+ T (Trm) cells define a distinct non-recirculating subset. Trm cells constitute a first line of defense against local infections in barrier tissues, but they are also found in non-barrier tissues and play a role in antitumo
Externí odkaz: https://doaj.org/article/9f1acf5cb4964f84ac35dd1114cf6bcb
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5
Akademický článek
Innate Immune Function of Mitochondrial Metabolism
Autor: David Sancho, Michel Enamorado, Johan Garaude
Publikováno v: Frontiers in Immunology, Vol 8 (2017)
Sensing of microbe-associated molecular patterns or danger signals by innate immune receptors drives a complex exchange of information. Innate receptor signaling not only triggers transcriptional events but also induces profound changes in metabolic
Externí odkaz: https://doaj.org/article/f0dc0566a89b4d118fbc890f939ec1ae
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9
Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections
Autor: Paola Brandi, Laura Conejero, Francisco J. Cueto, Sarai Martínez-Cano, Gillian Dunphy, Manuel J. Gómez, Carlos Relaño, Paula Saz-Leal, Michel Enamorado, Ana Quintas, Ana Dopazo, Joaquín Amores-Iniesta, Carlos del Fresno, Estanislao Nistal-Villán, Carlos Ardavín, Antonio Nieto, Miguel Casanovas, José Luis Subiza, David Sancho
Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
Cell Reports
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Cell Reports, volume 39, issue 1
Summary MV130 is an inactivated polybacterial mucosal vaccine that confers protection to patients against recurrent respiratory infections, including those of viral etiology. However, its mechanism of action remains poorly understood. Here, we find t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6655ea6db963d630136bc10e9a6c7b72
http://hdl.handle.net/20.500.12105/15092
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10
DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells
Autor: Alexis J. Combes, Santiago Zelenay, Christian P. Bromley, Matthew F. Krummel, Ignacio Melero, Paola Brandi, Alfonso R. Sánchez-Paulete, Carlos del Fresno, Manuel Gómez, Elena Hernández-García, Francisco J. Cueto, Michel Enamorado, Ruth Conde-Garrosa, Salvador Iborra, David Sancho, Santos Mañes
Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
Bromley, C 2021, ' DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells ', Journal for ImmunoTherapy of Cancer . https://doi.org/10.1136/jitc-2020-002054
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Journal for immunotherapy of cancer, vol 9, iss 5
Conventional type 1 dendritic cells (cDC1s) are central to antitumor immunity and their presence in the tumor microenvironment associates with improved outcomes in patients with cancer. DNGR-1 (CLEC9A) is a dead cell-sensing receptor highly restricte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e719150dc3d908f46d05f4443ec98bd
http://hdl.handle.net/20.500.12105/15091
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