Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Michel Desjarlais"'
Autor:
Sylvie Dussault, Michel Desjarlais, Nozha Raguema, Eric Boilard, Sylvain Chemtob, Alain Rivard
Publikováno v:
Cells, Vol 13, Iss 15, p 1243 (2024)
MicroRNAs (miRs) regulate physiological and pathological processes, including ischemia-induced angiogenesis and neovascularization. They can be transferred between cells by extracellular vesicles (EVs). However, the specific miRs that are packaged in
Externí odkaz:
https://doaj.org/article/d4281f5eaa49431e80ee70acc3c9a436
Autor:
Pakiza Ruknudin, Ali Riza Nazari, Maelle Wirth, Isabelle Lahaie, Emmanuel Bajon, Alain Rivard, Sylvain Chemtob, Michel Desjarlais
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13185 (2023)
Endothelial Progenitor Cells (EPCs) can actively participate in revascularization in oxygen-induced retinopathy (OIR). Yet the mechanisms responsible for their dysfunction is unclear. Nogo-A, whose function is traditionally related to the inhibition
Externí odkaz:
https://doaj.org/article/1d98e29aca94479f85b9148f33266d26
Autor:
Rabah Dabouz, Colin W. H. Cheng, Pénélope Abram, Samy Omri, Gael Cagnone, Khushnouma Virah Sawmy, Jean-Sébastien Joyal, Michel Desjarlais, David Olson, Alexander G. Weil, William Lubell, José Carlos Rivera, Sylvain Chemtob
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-19 (2020)
Abstract Background Inflammation and particularly interleukin-1β (IL-1β), a pro-inflammatory cytokine highly secreted by activated immune cells during early AMD pathological events, contribute significantly to retinal neurodegeneration. Here, we id
Externí odkaz:
https://doaj.org/article/506aa30b38074c1d9d6c7c66eb9f544b
Autor:
Michel Desjarlais, Pakiza Ruknudin, Maëlle Wirth, Isabelle Lahaie, Rabah Dabouz, José Carlos Rivera, Tiffany Habelrih, Samy Omri, Pierre Hardy, Alain Rivard, Sylvain Chemtob
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Background and AimInsufficient post-ischemic neovascularization is an initial key step in the pathogenesis of Oxygen-Induced Retinopathy (OIR). During neovascularization, pro-angiogenic cells (PACs) are mobilized from the bone marrow and integrate in
Externí odkaz:
https://doaj.org/article/8897c27c0d2f4502b53fdb07ee39e51b
Autor:
Michel Desjarlais, Maëlle Wirth, Isabelle Lahaie, Pakiza Ruknudin, Pierre Hardy, Alain Rivard, Sylvain Chemtob
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The coronavirus disease 2019 (COVID-19) pandemic has become the number one health problem worldwide. As of August 2020, it has affected more than 18 million humans and caused over 700,000 deaths worldwide. COVID-19 is an infectious disease that can l
Externí odkaz:
https://doaj.org/article/8fe24b3ba93d4da6aed51fe0bc09a690
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
BackgroundClassical cardiovascular risk factors (CRFs) are associated with impaired angiogenic activities of bone marrow–derived proangiogenic cells (PACs) related to peripheral artery diseases (PADs) and ischemia-induced neovascularization. MicroR
Externí odkaz:
https://doaj.org/article/0356c733f27a4237a1d3977eb7b88125
Autor:
Diane N. Sayah, Tianwei E. Zhou, Samy Omri, Javier Mazzaferri, Christiane Quiniou, Maëlle Wirth, France Côté, Rabah Dabouz, Michel Desjarlais, Santiago Costantino, Sylvain Chemtob
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Retinopathy of prematurity (ROP) is the leading cause of blindness in neonates. Inflammation, in particular interleukin-1β (IL-1β), is increased in early stages of the disorder, and contributes to inner and outer retinal vasoobliteration in the oxy
Externí odkaz:
https://doaj.org/article/517d3ff6c4aa43ef846cb4aa5a9b4ca5
Autor:
Michel Desjarlais, Maëlle Wirth, José Carlos Rivera, Isabelle Lahaie, Rabah Dabouz, Samy Omri, Pakiza Ruknudin, Celine Borras, Sylvain Chemtob
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Background and AimsVascular degeneration is a hallmark in the pathogenesis of oxygen-induced retinopathy (OIR). Dysregulation of microRNAs (miRNAs), key regulators of genes expressions, has been implicated in the regulation of ocular angiogenesis. Ho
Externí odkaz:
https://doaj.org/article/a3af8494e69948a9855d7f4b472db4b9
Autor:
Raphael Mathieu, Sylvie Dussault, Michel Desjarlais, François Rivard, Wahiba Dhahri, Anik Cloutier, Anne-Monique Nuyt, Alain Rivard
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Adverse perinatal conditions can lead to developmental programming of cardiovascular diseases. Prematurely born infants are often exposed to high oxygen levels, which in animal models has been associated with endothelial dysfunction, hyperte
Externí odkaz:
https://doaj.org/article/f82ba77dde434355ab36b34a1d84dc4e
Autor:
Michel Desjarlais, Jose Carlos Rivera, Isabelle Lahaie, Gaël Cagnone, Maëlle Wirt, Samy Omri, Sylvain Chemtob
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218282 (2019)
BackgroundIschemic retinopathies (IRs) are leading causes of visual impairment. They are characterized by an initial phase of microvascular degeneration and a second phase of aberrant pre-retinal neovascularization (NV). microRNAs (miRNAs) regulate g
Externí odkaz:
https://doaj.org/article/623050ef1c944734bd2b321a91375b84