Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Michel Cogne"'
Autor:
Alberto Hernández-Barranco, Vanesa Santos, Marina S. Mazariegos, Eduardo Caleiras, Laura Nogués, Frédéric Mourcin, Simon Léonard, Christelle Oblet, Steve Genebrier, Delphine Rossille, Alberto Benguría, Alba Sanz, Enrique Vázquez, Ana Dopazo, Alejo Efeyan, Ana Ortega-Molina, Michel Cogne, Karin Tarte, Héctor Peinado
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113705- (2024)
Summary: Nerve growth factor receptor (NGFR) is expressed by follicular dendritic cells (FDCs). However, the role of NGFR in the humoral response is not well defined. Here, we study the effect of Ngfr loss on lymph node organization and function, dem
Externí odkaz:
https://doaj.org/article/633cda8ce4e244e3af309d6246a7a4de
Autor:
Natsuko Ueda, Marine Cahen, Jenny Leonard, Laurent Deleurme, Stéphane Dreano, Christophe Sirac, Anne Galy, Jérôme Moreaux, Yannic Danger, Michel Cogné
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract T-cell-based adoptive immunotherapy is a new pillar of cancer care. Tumor-redirected B cells could also contribute to therapy if their manipulation to rewire immunoglobulin (Ig) genes is mastered. We designed a single-chain Ig-encoding casse
Externí odkaz:
https://doaj.org/article/d68373b8483948dca616dd429ddf3831
Autor:
Stéphane Rodriguez, Mehdi Alizadeh, Claire Lamaison, Alexis Saintamand, Céline Monvoisin, Rachel Jean, Laurent Deleurme, Jose Ignacio Martin-Subero, Céline Pangault, Michel Cogné, Patricia Amé-Thomas, Karin Tarte
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/858fed6b609e452cb08824915c58ded1
Autor:
Audrey Dauba, Emmanuelle Näser, Dylan Andrieux, Michel Cogné, Yves Denizot, Ahmed Amine Khamlichi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Class switch recombination (CSR) plays an important role in adaptive immune response by enabling mature B cells to replace the initial IgM by another antibody class (IgG, IgE or IgA). CSR is preceded by transcription of the IgH constant gene
Externí odkaz:
https://doaj.org/article/26a02d3d617541f8a06c1cd5091d2815
Autor:
Stéphane Rodriguez, Mehdi Alizadeh, Claire Lamaison, Alexis Saintamand, Céline Monvoisin, Rachel Jean, Laurent Deleurme, Jose Ignacio Martin-Subero, Céline Pangault, Michel Cogné, Patricia Amé-Thomas, Karin Tarte
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionFollicular Lymphoma (FL) results from the malignant transformation of germinal center (GC) B cells. FL B cells display recurrent and diverse genetic alterations, some of them favoring their direct interaction with their cell microenvironm
Externí odkaz:
https://doaj.org/article/553582ad254a47af841a6fffdaa8e467
Autor:
Sébastien Bender, Vincent Javaugue, Alexis Saintamand, Maria Victoria Ayala, Mehdi Alizadeh, Matthieu Filloux, Virginie Pascal, Nathalie Gachard, David Lavergne, Fabienne Auroy, Michel Cogne, Frank Bridoux, Christophe Sirac, Arnaud Jaccard
POEMS syndrome is a rare multisystem disease due to an underlying plasma cell (PC) dyscrasia. The pathophysiology of the disease remains unclear but the role of the monoclonal immunoglobulin (Ig) light chain (LC) is strongly suspected, due to the hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d55e7642c8c55ff0fa37a1b4ad276e4
https://doi.org/10.1101/824722
https://doi.org/10.1101/824722
Autor:
Mélanie, Chesneau, Richard, Danger, Le Bot, Sabine, Cyrielle, Poulaouec, Matthieu, Filloux, Alexis, Saintamand, Florence, Glaudet, Florian, Dubois, Maxim, Durand, Lola, Jacquemont, Pierrick, Guerrif, Béatrice, Charreau, Magali, Giral, Michel, Cogne, Nicolas, Degauque, Sophie, Brouard
Publikováno v:
FOCIS 2019
FOCIS 2019, Jun 2019, Boston, United States
FOCIS 2019, Jun 2019, Boston, United States
International audience; B cells secreting granzyme B (GZMB+) with suppressive properties have been discovered in a growing number of immunological contexts, autoimmunity, chronic infection, and neoplasias, as well as in healthy volunteers under physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c0c204818991738a68c9460988220e7d
https://www.hal.inserm.fr/inserm-02161909
https://www.hal.inserm.fr/inserm-02161909
Autor:
Nicolas Denis-Lagache, Christelle Oblet, Tiffany Marchiol, Audrey Baylet, Ophélie Têteau, Iman Dalloul, Zeinab Dalloul, Lina Zawil, Ophélie Dézé, Jeanne Cook-Moreau, Alexis Saintamand, Hend Boutouil, Ahmed Amine Khamlichi, Claire Carrion, Sophie Péron, Sandrine Le Noir, Brice Laffleur, Michel Cogné
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIn mature B cells, activation-induced deaminase reshapes Ig genes through somatic hypermutation and class switch recombination of the Ig heavy chain (IgH) locus under control of its 3’ cis-regulatory region (3’RR). The 3’RR is itsel
Externí odkaz:
https://doaj.org/article/138b735a8308469d92f827d4c9644e6a
Autor:
Virginie Pascal, Marine Dupont, Paco de Rouault, David Rizzo, Delphine Rossille, Robin Jeannet, Thomas Daix, Bruno François, Steve Genebrier, Marie Cornic, Guillaume Monneret, Fabienne Venet, Juliette Ferrant, Mikael Roussel, Florian Reizine, Mathieu Le Souhaitier, Jean-Marc Tadié, Karin Tarte, Jean Feuillard, Michel Cogné
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106260- (2023)
Summary: To understand the fine differential elements that can lead to or prevent acute respiratory distress syndrome (ARDS) in COVID-19 patients, it is crucial to investigate the immune response architecture. We herein dissected the multiple layers
Externí odkaz:
https://doaj.org/article/58ef21d9940245f4ba16f156fcb8aa18
Autor:
Aurélien Frerou, Mathieu Lesouhaitier, Murielle Gregoire, Fabrice Uhel, Arnaud Gacouin, Florian Reizine, Caroline Moreau, Aurélie Loirat, Adel Maamar, Nicolas Nesseler, Amedeo Anselmi, Erwan Flecher, Jean-Philippe Verhoye, Yves Le Tulzo, Michel Cogné, Mikael Roussel, Karin Tarte, Jean-Marc Tadié
Publikováno v:
Critical Care, Vol 25, Iss 1, Pp 1-12 (2021)
Abstract Background Venoarterial extracorporeal membrane oxygenation (VA-ECMO) provides heart mechanical support in critically ill patients with cardiogenic shock. Despite important progresses in the management of patients under VA-ECMO, acquired inf
Externí odkaz:
https://doaj.org/article/dd82e871e091487eaed5cdcc69837e9b