Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Michel Claret"'
Autor:
Michel Claret, Laurent Combettes, Caroline Clair, Dien Tran, Thierry Tordjmann, Sylviane Boucherie
Publikováno v:
Journal of Hepatology. 39:489-495
Background/Aims : In the liver, InsP 3 -dependent agonists such as vasopressin and noradrenaline induce tightly coordinated sequences of intracellular Ca 2+ increases, leading to apparent unidirectional Ca 2+ waves. In previous works, we have postula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f5ba07106e3a0047ea76cfcbfdf137
https://doi.org/10.1016/s0168-8278(03)00289-7
https://doi.org/10.1016/s0168-8278(03)00289-7
Autor:
Michel Claret, Jocelyn Inamo, Isabelle Marty, Olivier Vallot, Philippe Jourdon, Anne-Marie Lompré, Laurent Combettes
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 20:1225-1235
Abstract —Despite intensive interest in the dedifferentiation process of vascular smooth muscle cells, very little data are available on intracellular Ca 2+ signaling. The present study was designed to investigate the evolution of the intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e3ffbf3254a25bdb0a09552d79a4a8
https://doi.org/10.1161/01.atv.20.5.1225
https://doi.org/10.1161/01.atv.20.5.1225
Autor:
Michel Claret, Geneviève Dupont, Laurent Combettes, Caroline Clair, Thierry Tordjmann, Stéphane Swillens
Publikováno v:
The FASEB Journal. 14:279-289
Intercellular calcium signals are propagated in multicellular hepatocyte systems as well as in the intact liver. The stimulation of connected hepatocytes by glycogenolytic agonists induces reproducible sequences of intracellular calcium concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801751adf171554c151ebdd46dd44144
https://doi.org/10.1096/fasebj.14.2.279
https://doi.org/10.1096/fasebj.14.2.279
Autor:
Thierry Durroux, Michel Claret, Dien Tran, Gilles Guillon, Arlette Forchioni, Marie Noelle Dufour, Nicole Stelly, René Seyer, Thierry Tordjmann
Publikováno v:
Journal of Histochemistry & Cytochemistry. 47:601-616
In freshly isolated rat hepatocyte multiplets, Ca2+ signals in response to vasopressin are highly organized. In this study we used specific probes to visualize, by fluorescence and confocal microscopy, the main signaling molecules involved in vasopre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c68186d72cacdd0eeb75f737df715e
https://doi.org/10.1177/002215549904700503
https://doi.org/10.1177/002215549904700503
Autor:
Laurent Combettes, Brigitte Berthon, E. Jacquemin, Gérard Feldmann, Amélie Moreau, Michel Claret, Thierry Tordjmann, Bernard Lardeux
Publikováno v:
ResearcherID
Morphological and functional heterogeneity of hepatocytes according to their position in the liver lobule has been known for many years. The digitonin-collagenase perfusion technique is widely used to study hepatocyte heterogeneity and has yielded re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9adc6c36551d04b58deac27e06893ecd
https://doi.org/10.1002/hep.510260630
https://doi.org/10.1002/hep.510260630
Autor:
Michel Laurent, Michel Claret
Publikováno v:
Journal of Theoretical Biology. 186:307-326
We propose a molecular model for InsP3-sensitive Ca2+ oscillations based on the allosteric properties of the InsP3 receptor/Ca2+ channel. Our model interprets the cooperatively towards InsP3 saturation, of calcium efflux from intravesicular stores as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9c1bfc2c29e5b8697f64525b7ad3e2
https://doi.org/10.1006/jtbi.1996.0365
https://doi.org/10.1006/jtbi.1996.0365
Publikováno v:
Gastroenterology. 111:1343-1352
BACKGROUND & AIMS: In multicellular systems of rat hepatocytes and in the intact liver, inositol 1,4,5-trisphosphate (IP3)-dependent agonists induce sequentially ordered calcium ion signals. The mechanisms by which sequential waves are oriented from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565bac3c2b68ff28ec44164b071fe136
https://doi.org/10.1053/gast.1996.v111.pm8898649
https://doi.org/10.1053/gast.1996.v111.pm8898649
Publikováno v:
Journal of Biological Chemistry. 271:3568-3574
Incubation of cerebellar microsomes with d-myo-inositol 1,4,5-trisphosphate (InsP3) (0.01 1 microM), at 4 or 20 degrees C in a cytosolic-like medium devoid of Ca2+ and Mg2+, followed by InsP3 removal, induced an increase in InsP3 binding determined w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e6340601b46c8fc5d0da54c3e61d21
https://doi.org/10.1074/jbc.271.7.3568
https://doi.org/10.1074/jbc.271.7.3568
Publikováno v:
ResearcherID
The effects of caffeine on agonist-induced changes in intracellular Ca2+ concentration ([Ca2+]i) were studied in single fura 2-loaded cells and suspensions of rat hepatocytes. In single cells, caffeine (5-10 mM) inhibited [Ca2+]i oscillations induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6daec39eb1b0aaead051048fd38583
https://doi.org/10.1042/bj3010737
https://doi.org/10.1042/bj3010737
Publikováno v:
ResearcherID
The monohydroxy bile acid taurolithocholate (TLC) causes a rapid and transient increase in free cytosolic Ca2+ concentration ([Ca2+]i) in suspensions of rat hepatocytes similar to that elicited by the InsP3-dependent hormone vasopressin. The effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6edd49f1305836b285fb7dc16a63be9
https://doi.org/10.1042/bj2870891
https://doi.org/10.1042/bj2870891