Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Michel Charlier"'
Autor:
Nathalie Gillard, Bertrand Castaing, Melanie Spotheim-Maurizot, Marie Běgusová, Michel Charlier, Denise Sy
Publikováno v:
Radiation Physics and Chemistry. 72:265-270
We discuss here modifications of DNA and protein radiolysis due to the interaction of these two partners in specific complexes. Experimental patterns of frank strand breaks (FSB) and alkali revealed breaks (ARB) obtained for DNA lac operator bound to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65980be82f90664183762b11db31126c
https://doi.org/10.1016/j.radphyschem.2004.01.009
https://doi.org/10.1016/j.radphyschem.2004.01.009
Autor:
Françoise Culard, Séverine Eon, Michel Charlier, Édouard Sèche, Melanie Spotheim-Maurizot, S. Bouffard
Publikováno v:
Biophysical Journal. 82(5):2373-2382
Upon γ -ray or argon ion irradiation of the lac repressor protein, its peptide chain is cleaved and the protein loses its lac operator-binding activity, as shown respectively by polyacrylamide gel electrophoresis and retardation gel electrophoresis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a761fe10fcbbc4ac8b1b82fe15313e98
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 19:141-158
RADACK was conceived to simulate the radiation-induced attack to different DNA forms and complexes. It allows to separately calculate the probability of attack to each reactive atom of the sugar and of the base and takes into account the sequence-dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a81283c29e26e9d1f45911a9a690c0e
https://doi.org/10.1080/07391102.2001.10506727
https://doi.org/10.1080/07391102.2001.10506727
Publikováno v:
Radiation Research. 156:110-117
Eon, S., Culard, F., Sy, D., Charlier, M. and Spotheim-Maurizot, M. Radiation Disrupts Protein-DNA Complexes through Damage to the Protein. The lac Repressor-Operator System. Radiat. Res. 156, 110-117 (2001). Binding of a protein to its cognate DNA s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6ea95a418c1b34e9d37799d82d3e60
https://doi.org/10.1667/0033-7587(2001)156[0110:rdpdct]2.0.co
https://doi.org/10.1667/0033-7587(2001)156[0110:rdpdct]2.0.co
Publikováno v:
Theoretical Chemistry Accounts: Theory, Computation, and Modeling (Theoretica Chimica Acta). 106:137-145
Among the DNA lesions induced by ionising radiation, one of the most abundant base modifications is that of guanine (G) into 8-oxo-7-hydro-2′-deoxyguanosine (oxoG). The Escherichia coli lac operator–lac repressor complex bearing one or several ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d397b2ebfe83a27456fe388706a077cc
https://doi.org/10.1007/s002140100253
https://doi.org/10.1007/s002140100253
Autor:
Eric Renault, Christine Videlot, Michel Charlier, Robert Pansu, Pascal Pernot, F. Tfibel, Marie-Pierre Fontaine-Aupart
Publikováno v:
Photochemistry and Photobiology. 70:829-840
The intercalating antitumoral drug pazelliptine (PZE) is able to photosensitize the formation of single- and double-strand breaks in supercoiled plasmid DNA and selective photocleavage at guanine residues is observed. In order to understand the mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47b8c9af60137b35e8eca26c011ea9cd
https://doi.org/10.1111/j.1751-1097.1999.tb08290.x
https://doi.org/10.1111/j.1751-1097.1999.tb08290.x
Autor:
Melanie Spotheim-Maurizot, Michel Charlier, Denise Sy, C. Durand, C. Savoye, C. Swenberg, S. Hugot
Publikováno v:
Theoretical Chemistry Accounts: Theory, Computation, and Modeling (Theoretica Chimica Acta). 101:114-120
Sequence-dependent variations of DNA structure modulate radiation-induced strand breakage. Thiols reduce breakage by scavenging damaging radiolytic OH . and repairing sugar radicals. As shown by sequencing gel electrophoresis, WR-1065 radioprotection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f842c5a6163e532ea22b555c48bd33a
https://doi.org/10.1007/s002140050416
https://doi.org/10.1007/s002140050416
Publikováno v:
International Journal of Radiation Biology. 75:913-917
Purpose: To extend to a quadruplex the stochastic model of radiolytic attack previously applied to a quasi-random duplex DNA. Materials and methods: The quadruplex structure is obtained from the PDB databank (first structure from 201D entry). The pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d35f63d9a6be5a5cc3ac715346db9958
https://doi.org/10.1080/095530099139971
https://doi.org/10.1080/095530099139971
Autor:
Denise Sy, V. Michalik, M. Begusova, L. Tartier, Michel Charlier, C. Savoye, Melanie Spotheim-Maurizot
Publikováno v:
Journal de Chimie Physique et de Physico-Chimie Biologique. 95:674-681
Pour etudier l'influence de la structure de l'ADN sur la probabilite d'induire des coupures simple brin par les radiations ionisantes, l'attaque par les radicaux OH est simulee par la methode de Monte Carlo. Nous avons calcule les probabilites relati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7304049d281b9f5607420f170dd9a46
https://doi.org/10.1051/jcp:1998177
https://doi.org/10.1051/jcp:1998177
Publikováno v:
International Journal of Radiation Biology. 73:45-51
To search for possible variations of radiosensitivity along a unimolecular DNA quadruplex and to use them as support for choosing one of the two possible structures proposed by NMR studies.The probability of radiation-induced frank strand breaks (FSB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4626f0c66bc0b87ff791cda9be302492
https://doi.org/10.1080/095530098142699
https://doi.org/10.1080/095530098142699