Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Michel Chamberland"'
Autor:
Jacques Drouin, Michel Chamberland, François Gilbert, Pepijn van den Munckhof, Daniel Lévesque
Publikováno v:
Journal of neurochemistry, 96(1), 160-170. Wiley-Blackwell
Preferential neurodegeneration of dopaminergic neurons in the ventral substantia nigra of the midbrain is a hallmark of Parkinson's disease. The homeobox transcription factor Pitx3 is similarly and selectively expressed in the same neurons. Pitx3 def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f85b2483e3ee08432f8e1306699a1c21
https://doi.org/10.1111/j.1471-4159.2005.03522.x
https://doi.org/10.1111/j.1471-4159.2005.03522.x
Autor:
Mario Maira, Sylvie Lesage, Alaka Mullick, Michel Chamberland, Jacques Drouin, Patrice Hugo, Alexandre Philips
Publikováno v:
Europe PubMed Central
Two important functions of glucocorticoids (Gc), namely, suppression of immune system function and feedback repression of the hypothalamo-pituitary-adrenal (HPA) axis, are mediated through repression of gene transcription. Previous studies have indic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8ff58b48e42a4f2d705eb2ead8bf33
https://doi.org/10.1128/mcb.17.10.5952
https://doi.org/10.1128/mcb.17.10.5952
Autor:
A. De Lean, Yu Lin Sun, Y. Gauthier, Thomas J. Schmidt, J. Drouin, Michel Chamberland, Mona Nemer
Publikováno v:
The EMBO Journal. 12:145-156
Previous studies defined a DNA element necessary for glucocorticoid repression of the pro-opiomelanocortin (POMC) gene. The glucocorticoid receptor (GR) binds this negative glucocorticoid response element (nGRE) with an in vitro affinity similar to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::411f996df4685a7e804791c6c71addfa
https://doi.org/10.1002/j.1460-2075.1993.tb05640.x
https://doi.org/10.1002/j.1460-2075.1993.tb05640.x
Publikováno v:
Development (Cambridge, England). 130(1)
Two closely related homeobox transcription factors, Pitx1 and Pitx2, have been implicated in patterning of lateral plate mesoderm derivatives: Pitx1 for specification of hindlimb identity and Pitx2 for determination of laterality. We show that, toget
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2bb4e582ccd93899a3286c006f691c
https://pubmed.ncbi.nlm.nih.gov/12441290
https://pubmed.ncbi.nlm.nih.gov/12441290
Publikováno v:
Molecular and cellular biology. 20(13)
Cell-specific transcription results from complex molecular interactions that involve the synergistic action of multiple transcription factors. Taken together, these interactions provide the molecular basis for the complex program of cell differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088c8004c4f462ea0be3f3628fc45b17
https://pubmed.ncbi.nlm.nih.gov/10848608
https://pubmed.ncbi.nlm.nih.gov/10848608
Publikováno v:
Development; January 2003, Vol. 130 Issue: 1 p45-55, 11p
Autor:
Michel Chamberland, Jon H. Condra, Michel Chrétien, J. Drouin, Richard A. F. Dixon, N G Seidah, Mona Nemer, Robert A. Zivin
Publikováno v:
Proceedings of the National Academy of Sciences. 81:6325-6329
A cDNA copy of the message encoding rat atrial natriuretic factor (ANF) has been cloned in Escherichia coli, and its nucleotide sequence was determined. ANF appears to be synthesized as a larger precursor, atrial pronatriodilatin. The cDNA has an ope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c589347b03b4eb3cf611cb0fe3296a5e
https://doi.org/10.1073/pnas.81.20.6325
https://doi.org/10.1073/pnas.81.20.6325
Publikováno v:
FEBS Letters. 193:54-58
The gene encoding pro-opiomelanocortin (POMC) presents unique regulatory features. In particular, glucocorticoids inhibit transcription of the POMC gene in the anterior pituitary, but not in the intermediate pituitary. In order to study the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38c34f8b872a29d89471af4b636d4d9a
https://doi.org/10.1016/0014-5793(85)80078-8
https://doi.org/10.1016/0014-5793(85)80078-8
Publikováno v:
Molecular and cellular biology. 7(11)
The pro-opiomelanocortin (POMC) gene is specifically expressed in corticotroph cells of the anterior pituitary. To define the POMC promoter sequences responsible for tissue-specific expression, we assessed POMC promoter activity by gene transfer into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c56bdb31c4d06b64d4901833628d54
https://pubmed.ncbi.nlm.nih.gov/3431549
https://pubmed.ncbi.nlm.nih.gov/3431549