Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Michel Cailleret"'
Autor:
Elie Frank, Michel Cailleret, Constantin Nelep, Pascal Fragner, Jérome Polentes, Elise Herardot, Lina El Kassar, Karine Giraud-Triboult, Christelle Monville, Karim Ben M’Barek
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background CRISPR/Cas9 editing systems are currently used to generate mutations in a particular gene to mimic a genetic disorder in vitro. Such “disease in a dish” models based on human pluripotent stem cells (hPSCs) offer the opportunit
Externí odkaz:
https://doaj.org/article/a0978364e13741ee98c9f4e6a67499fa
Autor:
Jérôme Polentes, Pavla Jendelova, Michel Cailleret, Holger Braun, Nataliya Romanyuk, Philippe Tropel, Marion Brenot, Valerie Itier, Christine Seminatore, Kathrin Baldauf, Karolina Turnovcova, Daniel Jirak, Marius Teletin, Julien Côme, Johana Tournois, Klaus Reymann, Eva Sykova, Stéphane Viville, Brigitte Onteniente
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Human induced pluripotent stem cells (hiPSCs) are a most appealing source for cell replacement therapy in acute brain lesions. We evaluated the potential of hiPSC therapy in stroke by transplanting hiPSC-derived neural progenitor cells (NPCs) into th
Externí odkaz:
https://doaj.org/article/f3cf046e2ed744fcb08b607d843f1e68
Autor:
Jérôme Polentes, Hélène Polvèche, Cécile Martinat, Axel Sciauvaud, Maria-Gabriela Boza-Moran, Laetitia Aubry, Marc Peschanski, Margot Jarrige, Sandra Pourtoy-Brasselet, Michel Cailleret, Eric Chevet
Publikováno v:
American Journal of Human Genetics
American Journal of Human Genetics, 2021, 108 (11), pp.2171-2185. ⟨10.1016/j.ajhg.2021.10.001⟩
American Journal of Human Genetics, Elsevier (Cell Press), 2021, 108 (11), pp.2171-2185. ⟨10.1016/j.ajhg.2021.10.001⟩
Am J Hum Genet
American Journal of Human Genetics, 2021, 108 (11), pp.2171-2185. ⟨10.1016/j.ajhg.2021.10.001⟩
American Journal of Human Genetics, Elsevier (Cell Press), 2021, 108 (11), pp.2171-2185. ⟨10.1016/j.ajhg.2021.10.001⟩
Am J Hum Genet
International audience; Recent studies indicate that neurodegenerative processes that appear during childhood and adolescence in individuals with Wolfram syndrome (WS) occur in addition to early brain development alteration, which is clinically silen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48846496992065aec0d0d30ad68bd9b0
https://doi.org/10.1016/j.ajhg.2021.10.001
https://doi.org/10.1016/j.ajhg.2021.10.001
Autor:
Céline Leteur, Margot Jarrige, Jérôme Polentes, Hélène Polvèche, Denis Furling, Cécile Martinat, Christian Pinset, Alexandre Carteron, Julie Tahraoui-Bories, Jean-Paul Concordet, Antoine Mérien, Michel Cailleret, Jean-Baptiste Dupont
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, 2022, 31 (1), pp.41-56. ⟨10.1093/hmg/ddab218⟩
Human Molecular Genetics, 2022, 31 (1), pp.41-56. ⟨10.1093/hmg/ddab218⟩
Alternative splicing has emerged as a fundamental mechanism for the spatiotemporal control of development. A better understanding of how this mechanism is regulated has the potential not only to elucidate fundamental biological principles, but also t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8b1cb933f2b8a12fa650969e5a9484
https://pubmed.ncbi.nlm.nih.gov/34312665
https://pubmed.ncbi.nlm.nih.gov/34312665
Autor:
Laetitia, Barrault, Jacqueline, Gide, Tingting, Qing, Lea, Lesueur, Jorg, Tost, Jerome Alexandre, Denis, Michel, Cailleret, Laetitia, Aubry, Marc, Peschanski, Cécile, Martinat, Sandrine, Baghdoyan
Publikováno v:
Cells
Substantial variations in differentiation properties have been reported among human pluripotent cell lines (hPSC), which could affect their utility and clinical safety. We characterized the variable osteogenic capacity observed between different huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed33c0b738993db8a632cd615ca4c7cf
https://pubmed.ncbi.nlm.nih.gov/31779280
https://pubmed.ncbi.nlm.nih.gov/31779280
Autor:
Alexandra Benchoua, Marie Lasbareilles, Michel Cailleret, Valentin Ruillier, Marc Peschanski, Laure Chatrousse, Claire Boissart, Gurvan Mahé, Johana Tournois
Publikováno v:
JCI insight. 5(4)
Lesch-Nyhan disease (LND) is a rare monogenic disease caused by deficiency of the salvage pathway enzyme hypoxanthine-guanine phosphoribosyltransferase (HGPRT). LND is characterized by severe neuropsychiatric symptoms that currently cannot be treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8465eb41ebf972498c846cfa951e5562
https://pubmed.ncbi.nlm.nih.gov/31990683
https://pubmed.ncbi.nlm.nih.gov/31990683
Autor:
Margot Jarrige, Julie Bigarreau, Gabriel Vachey, Morgane Louessard, Nicole Déglon, Anselme L. Perrier, Michel Cailleret
Publikováno v:
Pathogenic mechanisms.
In Huntington disease (HD), the most affected cells are the GABA-releasing medium spiny neurons (MSN) of the striatum, the subcortical brain structure that controls body movement. DARPP32 (dopamine- and 3’,5’-cyclic adenosine monophosphate-regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bb5bc10692aa7747ecb2218000dba9a
https://doi.org/10.1136/jnnp-2018-ehdn.38
https://doi.org/10.1136/jnnp-2018-ehdn.38
Autor:
Tingting Qing, Jacqueline Gide, Jérôme Alexandre Denis, Laetitia Barrault, Laetitia Aubry, Michel Cailleret, Léa Lesueur, Sandrine Baghdoyan, Cécile Martinat, Jörg Tost, Marc Peschanski
Publikováno v:
Cells
Volume 8
Issue 12
Volume 8
Issue 12
Substantial variations in differentiation properties have been reported among human pluripotent cell lines (hPSC), which could affect their utility and clinical safety. We characterized the variable osteogenic capacity observed between different huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef1c38f3bb5981488942c9a259c02a4
https://doi.org/10.3390/cells8121523
https://doi.org/10.3390/cells8121523
Autor:
Camille Nicoleau, Michel Cailleret, Marc Lechuga, Benjamin Brinon, Martine Guillermier, Emmanuel Brouillet, Caroline Bonnefond, Laetitia Francelle, Maxime Feyeux, Pedro Viegas, Gwenaëlle Auregan, Cécile Martinat, Marc Peschanski, Elena Cattaneo, Anselme L. Perrier, Jérémie Charbord, Pauline Poydenot, Fabrice Casagrande
Publikováno v:
STEM CELLS
STEM CELLS; Vol 31
STEM CELLS; Vol 31
Decreased expression of neuronal genes such as brain-derived neurotrophic factor (BDNF) is associated with several neurological disorders. One molecular mechanism associated with Huntington disease (HD) is a discrete increase in the nuclear activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5480590d7794d80b400c24094e68bf4a
Autor:
Yacine Laâbi, Johana Tournois, Julien Côme, Pascal Fragner, Michel Cailleret, Philippe Tropel, Christine Varela, Marc Peschanski, Céline Moutou, Stéphane Viville
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 46:376-385
Pre-implantation genetic diagnosis allows the characterisation of embryos that carry a gene responsible for a severe monogenic disease and to transfer to the mother’s uterus only the unaffected one(s). The genetically affected embryos can be used t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88dbf0bf1add0d95f70a10735bae7011
https://doi.org/10.1007/s11626-010-9300-8
https://doi.org/10.1007/s11626-010-9300-8