Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Michel Abou‐Samra"'
Autor:
Isabelle S. Massart, Axell‐Natalie Kouakou, Nathan Pelet, Pascale Lause, Olivier Schakman, Audrey Loumaye, Michel Abou‐Samra, Louise Deldicque, Laure B. Bindels, Sonia M. Brichard, Jean‐Paul Thissen
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 3, Pp 919-933 (2024)
Abstract Background Cancer cachexia is a life‐threatening, inflammation‐driven wasting syndrome that remains untreatable. Adiponectin, the most abundant adipokine, plays an important role in several metabolic processes as well as in inflammation
Externí odkaz:
https://doaj.org/article/0b9792a33b6040ba97dde84ba7b5169d
Challenging Sarcopenia: Exploring AdipoRon in Aging Skeletal Muscle as a Healthspan-Extending Shield
Autor:
Camille M. Selvais, Maria A. Davis-López de Carrizosa, Romain Versele, Nicolas Dubuisson, Laurence Noel, Sonia M. Brichard, Michel Abou-Samra
Publikováno v:
Antioxidants, Vol 13, Iss 9, p 1073 (2024)
Sarcopenia, characterized by loss of muscle mass, quality, and function, poses significant risks in aging. We previously demonstrated that long-term treatment with AdipoRon (AR), an adiponectin receptor agonist, alleviated myosteatosis and muscle deg
Externí odkaz:
https://doaj.org/article/33fd684899a1494f905b661ff7d1186c
Autor:
Camille M. Selvais, María A. Davis‐López de Carrizosa, Maxime Nachit, Romain Versele, Nicolas Dubuisson, Laurence Noel, Justine Gillard, Isabelle A. Leclercq, Sonia M. Brichard, Michel Abou‐Samra
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 464-478 (2023)
Abstract Background Obesity among older adults has increased tremendously. Obesity accelerates ageing and predisposes to age‐related conditions and diseases, such as loss of endurance capacity, insulin resistance and features of the metabolic syndr
Externí odkaz:
https://doaj.org/article/c5120c52540e45bfbd71c0373a8c35b5
Autor:
Nicolas Dubuisson, María A. Davis-López de Carrizosa, Romain Versele, Camille M. Selvais, Laurence Noel, P. Y. D. Van den Bergh, Sonia M. Brichard, Michel Abou-Samra
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundDuchenne muscular dystrophy (DMD) is the most common inherited human myopathy. Typically, the secondary process involving severe inflammation and necrosis exacerbate disease progression. Previously, we reported that the NLRP3 inflammasome c
Externí odkaz:
https://doaj.org/article/65d0391ca98e4808b0062c758339e7e1
Autor:
Nicolas Dubuisson, Romain Versele, Maria A. Davis-López de Carrizosa, Camille M. Selvais, Laurence Noel, Chloé Planchon, Peter Y. K. Van den Bergh, Sonia M. Brichard, Michel Abou-Samra
Publikováno v:
Cells, Vol 12, Iss 16, p 2101 (2023)
Duchenne muscular dystrophy (DMD) is one of the most devastating myopathies, where severe inflammation exacerbates disease progression. Previously, we demonstrated that adiponectin (ApN), a hormone with powerful pleiotropic effects, can efficiently i
Externí odkaz:
https://doaj.org/article/731521ed2bfd4d5f9dde73441965f2ca
Autor:
Michel Abou‐Samra, Camille M. Selvais, Raphael Boursereau, Sophie Lecompte, Laurence Noel, Sonia M. Brichard
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 2, Pp 518-533 (2020)
Abstract Background Adiponectin (ApN) is a hormone known to exhibit insulin‐sensitizing, fat‐burning, and anti‐inflammatory properties in several tissues, including the skeletal muscle. Duchenne muscular dystrophy (DMD) is a devastating disease
Externí odkaz:
https://doaj.org/article/af73131b524c46b8999ce7766d29d5ca
Autor:
Nicolas Dubuisson, Romain Versele, Chloé Planchon, Camille M. Selvais, Laurence Noel, Michel Abou-Samra, María A. Davis-López de Carrizosa
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16080 (2022)
Duchenne muscular dystrophy (DMD) is a progressive disease caused by the loss of function of the protein dystrophin. This protein contributes to the stabilisation of striated cells during contraction, as it anchors the cytoskeleton with components of
Externí odkaz:
https://doaj.org/article/9b3c71e3af9d4fce9d80cffc5bfc6021
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-17 (2018)
Abstract Background The hormone adiponectin (ApN) exerts powerful anti-inflammatory effects on skeletal muscle and can reverse devastating myopathies, like Duchenne muscular dystrophy (DMD), where inflammation exacerbates disease progression. The NLR
Externí odkaz:
https://doaj.org/article/00228c74e46949909ca1905b6fc9cd90
Autor:
Nicolas Dubuisson, Romain Versele, María A. Davis-López de Carrizosa, Camille M. Selvais, Sonia M. Brichard, Michel Abou-Samra
Publikováno v:
Cells, Vol 10, Iss 11, p 3023 (2021)
Over the last decade, innate immune system receptors and sensors called inflammasomes have been identified to play key pathological roles in the development and progression of numerous diseases. Among them, the nucleotide-binding oligomerization doma
Externí odkaz:
https://doaj.org/article/c31c9aae9525475bbf1f29b986dc33c1
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2620 (2020)
Adiponectin (ApN) is a hormone abundantly secreted by adipocytes and it is known to be tightly linked to the metabolic syndrome. It promotes insulin-sensitizing, fat-burning, and anti-atherosclerotic actions, thereby effectively counteracting several
Externí odkaz:
https://doaj.org/article/68b94626c898439e8e04cf2c7387f8f9