Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Michel Kranendonk"'
Publikováno v:
Journal of Xenobiotics, Vol 14, Iss 2, Pp 575-603 (2024)
Progesterone receptor membrane component 1 (PGRMC1) is one of few proteins that have been recently described as direct modulators of the activity of human cytochrome P450 enzymes (CYP)s. These enzymes form a superfamily of membrane-bound hemoproteins
Externí odkaz:
https://doaj.org/article/c881402b56ee4ab29ec0f1303888a296
Autor:
Nádia Vital, Ana Catarina Gramacho, Mafalda Silva, Maria Cardoso, Paula Alvito, Michel Kranendonk, Maria João Silva, Henriqueta Louro
Publikováno v:
Foods, Vol 13, Iss 11, p 1690 (2024)
Considering the increase in the production and use of nanomaterials (NM) in food/feed and food contact materials, novel strategies for efficient and sustainable hazard characterization, especially in the early stages of NM development, have been prop
Externí odkaz:
https://doaj.org/article/ee84c5ce260c4bf583d0065df1083ffe
Autor:
Francisco Esteves, Cristina M. M. Almeida, Sofia Silva, Inês Saldanha, Philippe Urban, José Rueff, Denis Pompon, Gilles Truan, Michel Kranendonk
Publikováno v:
Biomolecules, Vol 13, Iss 7, p 1083 (2023)
A unique cytochrome P450 (CYP) oxidoreductase (CPR) sustains activities of human microsomal CYPs. Its function requires toggling between a closed conformation enabling electron transfers from NADPH to FAD and then FMN cofactors and open conformations
Externí odkaz:
https://doaj.org/article/f62d15d3be7b4883af44a3ed7f77817f
Autor:
Ana Cabrita, Alexandra M. Medeiros, Telmo Pereira, António Sebastião Rodrigues, Michel Kranendonk, César S. Mendes
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104541- (2022)
Summary: Adequate alternatives to conventional animal testing are needed to study developmental neurotoxicity (DNT). Here, we used kinematic analysis to assess DNT of known (toluene (TOL) and chlorpyrifos (CPS)) and putative (β-N-methylamino-L-alani
Externí odkaz:
https://doaj.org/article/472de6d11e1f4a76857f1b46db1db26d
Publikováno v:
Journal of Xenobiotics, Vol 11, Iss 3, Pp 94-114 (2021)
Human Cytochrome P450 (CYP) enzymes constitute a superfamily of membrane-bound hemoproteins that are responsible for the metabolism of a wide variety of clinically, physiologically, and toxicologically important compounds. These heme-thiolate monooxy
Externí odkaz:
https://doaj.org/article/f62a7b0591ab4024b2099490050f7ec1
Autor:
Dr. Célia M. Silveira, Dr. Patrícia R. Rodrigues, Dr. Wissam Ghach, Dr. Sofia A. Pereira, Dr. Francisco Esteves, Dr. Michel Kranendonk, Dr. Mathieu Etienne, Prof. Dr. M. Gabriela Almeida
Publikováno v:
ChemElectroChem, Vol 8, Iss 3, Pp 500-507 (2021)
Abstract The direct electrochemical response of membrane‐bound human cytochrome P450 1A2 (CYP1A2) was studied on pyrolytic graphite electrodes, while encapsulated in a sol‐gel matrix. The enzymatic reduction of O2 was evaluated in the presence an
Externí odkaz:
https://doaj.org/article/34d7163ea3fb46918bd84e76f4684dc9
Publikováno v:
Nanomaterials, Vol 12, Iss 19, p 3375 (2022)
Cellulose nanomaterials (CNMs) have emerged recently as an important group of sustainable bio-based nanomaterials (NMs) with potential applications in multiple sectors, including the food, food packaging, and biomedical fields. The widening of these
Externí odkaz:
https://doaj.org/article/7eba501cffab47f9b2342f0b13ce6217
Autor:
Francisco Esteves, Diana Campelo, Bruno Costa Gomes, Philippe Urban, Sophie Bozonnet, Thomas Lautier, José Rueff, Gilles Truan, Michel Kranendonk
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/4feb1c7e46344f58a5e4ad60ebee8dd1
Autor:
Francisco Esteves, Diana Campelo, Bruno Costa Gomes, Philippe Urban, Sophie Bozonnet, Thomas Lautier, José Rueff, Gilles Truan, Michel Kranendonk
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
NADPH cytochrome P450 oxidoreductase (CPR) is the obligatory electron supplier that sustains the activity of microsomal cytochrome P450 (CYP) enzymes. The variant nature of the isoform-specific proximal interface of microsomal CYPs indicates that CPR
Externí odkaz:
https://doaj.org/article/78cc9bf1507040fe9210808633b8f4ef
Autor:
Diana Campelo, Thomas Lautier, Philippe Urban, Francisco Esteves, Sophie Bozonnet, Gilles Truan, Michel Kranendonk
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/d0cd274b52a4418d9e0aa7aee26dcca0