Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Michel‐Edwar Mickael"'
Autor:
Michel-Edwar Mickael, Norwin Kubick, Atanas G. Atanasov, Petr Martinek, Jarosław Olav Horbańczuk, Nikko Floretes, Michael Michal, Tomas Vanecek, Justyna Paszkiewicz, Mariusz Sacharczuk, Piotr Religa
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8301-8319 (2024)
The accurate identification of the primary tumor origin in metastatic cancer cases is crucial for guiding treatment decisions and improving patient outcomes. Copy number alterations (CNAs) and copy number variation (CNV) have emerged as valuable geno
Externí odkaz:
https://doaj.org/article/e6185171faa7413aaa28f25c0fe5414d
Autor:
Mariusz Sacharczuk, Michel-Edwar Mickael, Norwin Kubick, Agnieszka Kamińska, Jarosław Olav Horbańczuk, Atanas G. Atanasov, Piotr Religa, Michał Ławiński
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 7846-7861 (2024)
Amyotrophic Lateral Sclerosis (ALS) is a poorly understood and fatal disease. It has a low prevalence and a 2–4 year survival period. Various theories and hypotheses relating to its development process have been proposed, albeit with no breakthroug
Externí odkaz:
https://doaj.org/article/0ddd927431f74d87aeb9e9b0d12034f7
Autor:
Marzena Łazarczyk, Ewa Kurzejamska, Michel-Edwar Mickael, Piotr Poznański, Dominik Skiba, Mariusz Sacharczuk, Zbigniew Gaciong, Piotr Religa
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 4, Pp 3446-3461 (2023)
Colorectal cancer is the third most frequently diagnosed cancer in the world. Despite extensive studies and apparent progress in modern strategies for disease control, the treatment options are still not sufficient and effective, mostly due to freque
Externí odkaz:
https://doaj.org/article/e6df83c6d6c44e2e8cb9fffc46bec072
Autor:
Olena Litvinova, Andy Wai Kan Yeung, Fabian Peter Hammerle, Michel-Edwar Mickael, Maima Matin, Maria Kletecka-Pulker, Atanas G. Atanasov, Harald Willschke
Publikováno v:
Pharmaceuticals, Vol 17, Iss 3, p 395 (2024)
Adverse drug reactions continue to be not only one of the most urgent problems in clinical medicine, but also a social problem. The aim of this study was a bibliometric analysis of the use of digital technologies to prevent adverse drug reactions and
Externí odkaz:
https://doaj.org/article/1b1939a6839842798ed12060cc7ad3b4
Autor:
Suniti Bhaumik, Marzena Łazarczyk, Norwin Kubick, Pavel Klimovich, Agata Gurba, Justyna Paszkiewicz, Patrycja Teodorowicz, Tomasz Kocki, Jarosław Olav Horbańczuk, Gina Manda, Mariusz Sacharczuk, Michel-Edwar Mickael
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 1, Pp 628-648 (2023)
Regulatory T cell (Treg) suppression of conventional T cells is a central mechanism that ensures immune system homeostasis. The exact time point of Treg emergence is still disputed. Furthermore, the time of Treg-mediated suppression mechanisms’ eme
Externí odkaz:
https://doaj.org/article/d498a33de9cb4813a1f4af7d87ed0cd0
Autor:
Norwin Kubick, Patrick C. Henckell Flournoy, Pavel Klimovich, Gina Manda, Michel‐Edwar Mickael
Publikováno v:
Immunity, Inflammation and Disease, Vol 8, Iss 4, Pp 825-839 (2020)
Abstract The use of single‐cell RNA sequencing (scRNA‐seq) in microglial research is increasing rapidly. The basic workflow of this approach consists of isolating single cells, followed by sequencing. scRNA‐seq is capable of examining microglia
Externí odkaz:
https://doaj.org/article/7f2a62b2796844e3bfd9416d8651066d
Autor:
Alexandra Klimovich-Mickael, Norwin Kubick, Elena Milanesi, Maria Dobre, Marzena Łazarczyk, Baraba Wijas, Mariusz Sacharczuk, Michel-Edwar Mickael
Publikováno v:
Frontiers in Global Women's Health, Vol 2 (2021)
The effect of social lockdown during the COVID-19 outbreak on female aggressiveness is not well known. The strict measures of lockdown have resulted in millions of people, worldwide, confined to their homes during the pandemic. However, the consequen
Externí odkaz:
https://doaj.org/article/60a9e66f6b9c44b19434a0eb85fb7120
Autor:
Norwin Kubick, Pavel Klimovich, Irmina Bieńkowska, Piotr Poznanski, Marzena Łazarczyk, Mariusz Sacharczuk, Michel-Edwar Mickael
Publikováno v:
Insects, Vol 12, Iss 10, p 882 (2021)
Understanding the evolutionary relationship between immune cells and the blood–brain barrier (BBB) is important to devise therapeutic strategies. In vertebrates, immune cells follow either a paracellular or a transcellular pathway to infiltrate the
Externí odkaz:
https://doaj.org/article/43f4471aaf284ba4a82049e74a156605
Autor:
Norwin Kubick, Patrick C. Henckell Flournoy, Ana-Maria Enciu, Gina Manda, Michel-Edwar Mickael
Publikováno v:
Pharmaceutics, Vol 12, Iss 9, p 880 (2020)
The effect of Alzheimer’s disease (AD) medications on CD4+ T cells homing has not been thoroughly investigated. CD4+ T cells could both exacerbate and reduce AD symptoms based on their infiltrating subpopulations. Proinflammatory subpopulations suc
Externí odkaz:
https://doaj.org/article/1910600c11114e57b588b615c888104d
Publikováno v:
Molecules, Vol 25, Iss 9, p 2155 (2020)
Repurposing drugs to target M1 macrophages inflammatory response in depression constitutes a bright alternative for commonly used antidepressants. Depression is a significant type of mood disorder, where patients suffer from pathological disturbances
Externí odkaz:
https://doaj.org/article/4b79124037c24bd985fab3685f457d5d