Hijacking of internal calcium dynamics by intracellularly residing viral rhodopsins

Autor: Ana-Sofia Eria-Oliveira, Mathilde Folacci, Anne Amandine Chassot, Sandrine Fedou, Nadine Thézé, Dmitrii Zabelskii, Alexey Alekseev, Ernst Bamberg, Valentin Gordeliy, Guillaume Sandoz, Michel Vivaudou

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)

Abstract Rhodopsins are ubiquitous light-driven membrane proteins with diverse functions, including ion transport. Widely distributed, they are also coded in the genomes of giant viruses infecting phytoplankton where their function is not settled. He

Externí odkaz: https://doaj.org/article/0cda7eb402034abe872f92cb1c70f4e5

Characterization of Loss-Of-Function KCNJ2 Mutations in Atypical Andersen Tawil Syndrome

Autor: Pauline Le Tanno, Mathilde Folacci, Jean Revilloud, Laurence Faivre, Gabriel Laurent, Lucile Pinson, Pascal Amedro, Gilles Millat, Alexandre Janin, Michel Vivaudou, Nathalie Roux-Buisson, Julien Fauré

Publikováno v: Frontiers in Genetics, Vol 12 (2021)

Andersen-Tawil Syndrome (ATS) is a rare disease defined by the association of cardiac arrhythmias, periodic paralysis and dysmorphic features, and is caused by KCNJ2 loss-of-function mutations. However, when extracardiac symptoms are atypical or abse

Externí odkaz: https://doaj.org/article/1eea676b9315439d98a82f282c9786d4

Hijacking of internal calcium dynamics by intracellularly residing rhodopsins

Autor: Ana-Sofia Eria-Oliveira, Mathilde Folacci, Anne Amandine Chassot, Sandrine Fedou, Nadine Thézé, Dmitrii Zabelskii, Alexey Alekseev, Ernst Bamberg, Valentin Gordeliy, Guillaume Sandoz, Michel Vivaudou

Rhodopsins are ubiquitous light-driven membrane proteins with diverse functions, including ion transport. Widely distributed, they are also coded in the genomes of giant viruses infecting phytoplankton where their function is not settled. We examined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b389d195ac14326b8a5fc5eb16f0957c
https://doi.org/10.1101/2023.05.25.542240

C-terminal engineering of CXCL12 and CCL5 chemokines: functional characterization by electrophysiological recordings.

Autor: Antoine Picciocchi, Lina Siaučiūnaiteė-Gaubard, Isabelle Petit-Hartlein, Rabia Sadir, Jean Revilloud, Lydia Caro, Michel Vivaudou, Franck Fieschi, Christophe Moreau, Corinne Vivès

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e87394 (2014)

Chemokines are chemotactic cytokines comprised of 70-100 amino acids. The chemokines CXCL12 and CCL5 are the endogenous ligands of the CXCR4 and CCR5 G protein-coupled receptors that are also HIV co-receptors. Biochemical, structural and functional s

Externí odkaz: https://doaj.org/article/35593aa1e1b64bee9b6ae6067ce66ddf

Nanoscale co-organization and coactivation of AMPAR, NMDAR, and mGluR at excitatory synapses

Autor: Ana Paula Menegolla, Terrence J. Sejnowski, Tomas M. Bartol, Julia Goncalves, Come Camus, Michel Vivaudou, Florian Levet, Daniel Choquet, Eric Hosy, Jean-Baptiste Sibarita

Publikováno v: Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, 117 (25), pp.14503-14511. ⟨10.1073/pnas.1922563117⟩
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (25), pp.14503-14511. ⟨10.1073/pnas.1922563117⟩
Proc Natl Acad Sci U S A

International audience; The nanoscale co-organization of neurotransmitter receptors facing presynaptic release sites is a fundamental determinant of their coactivation and of synaptic physiology. At excitatory synapses, how endogenous AMPARs, NMDARs,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a0ed12b242bbe4541a5c358a3e38bb