Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Michel, Seman"'
Autor:
Jean-Marcel Julien Tronchet, Michèle Reboud-Ravaux, Serge Kirkiacharian, Michel Seman, Julien Dumond
Publikováno v:
Letters in Drug Design & Discovery. 17:818-825
Background:Reverse Transcriptase (RT) of immunodeficiency virus type-1 (HIV-1) remains an essential target for new antiretroviral therapies. Non-nucleoside reverse transcriptase inhibitors (or NNRTIs) constitute a major class of RT inhibitors whose c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::412e4dba6e02beb755db4dc49aab0383
https://doi.org/10.2174/1570180816666190723121845
https://doi.org/10.2174/1570180816666190723121845
Autor:
Friedrich Haag, Dunja Freese, Felix Scheublein, Wiebke Ohlrogge, Sahil Adriouch, Michel Seman, Friedrich Koch-Nolte
Publikováno v:
Clinical and Developmental Immunology, Vol 9, Iss 4, Pp 197-202 (2002)
Externí odkaz:
https://doaj.org/article/99c0b226e41047aaa92db6f54fa7b393
Publikováno v:
Microbes and Infection. 14:1284-1292
Endogenous danger signals released during cell damage contribute to alert the immune system. Typically, their release results in the activation and maturation of innate immune cells, and the production of pro-inflammatory cytokines. In addition, extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed702e8d4608e6e79be5536ef73ea02
https://doi.org/10.1016/j.micinf.2012.05.011
https://doi.org/10.1016/j.micinf.2012.05.011
Autor:
Tim Sparwasser, Sahil Adriouch, Friedrich Koch-Nolte, Michel Seman, Jochen Huehn, Björn Rissiek, Friedrich Haag, Sandra Hubert, Olivier Boyer, Katjana Klages
Publikováno v:
The Journal of Experimental Medicine
Extracellular NAD+ affects the survival and function of regulatory T cells, and NAD-mediated depletion of regulatory T cells promotes anti-tumor responses in mice.
CD4+CD25+FoxP3+ regulatory T cells (T reg cells) play a major role in the control
CD4+CD25+FoxP3+ regulatory T cells (T reg cells) play a major role in the control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528e60603fc0f875707c62360dfed9c2
https://doi.org/10.1084/jem.20091154
https://doi.org/10.1084/jem.20091154
Autor:
Patrícia dos Santos Carneiro, Michel Seman, Marcelo De Franco, Tommaso A. Dragani, Antonella Galvan, Olga M. Ibañez, Orlando Garcia Ribeiro, Wafa Hanna Koury Cabrera, José Ricardo Jensen, Francisca Vorraro, Nancy Starobinas
Publikováno v:
The Journal of Immunology. 185:1616-1621
Genome-wide linkage analysis using single nucleotide polymorphism arrays was carried out in pedigrees of mice differing in the extent of acute inflammatory response (AIRmax or AIRmin). The AIR phenotype was determined by quantifying the number of inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cdb782f99eb7e8c24c21cfcce807b4a
https://doi.org/10.4049/jimmunol.1000358
https://doi.org/10.4049/jimmunol.1000358
Autor:
Michel Seman, Friedrich Haag, George R. Dubyak, Friedrich Koch-Nolte, Anette Brass, Shiyuan Hong
Publikováno v:
Purinergic Signalling. 5:369-383
ADP-ribosylation of cell surface proteins in mammalian cells is a post-translational modification by which ecto-ADP-ribosyltransferases (ARTs) transfer ADP-ribose from extracellular NAD to protein targets. The ART2 locus at murine chromosome 7 encomp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ca8eeb6ad60a479897110066ad857d
https://doi.org/10.1007/s11302-009-9162-2
https://doi.org/10.1007/s11302-009-9162-2
Autor:
Sahil Adriouch, Severine Pechberty, Friedrich Haag, Friedrich Koch-Nolte, Sandra Hubert, Michel Seman
Publikováno v:
The Journal of Immunology. 179:186-194
Mono ADP-ribosyltransferase 2 (ART2) is an ectoenzyme expressed on mouse T lymphocytes, which catalyze the transfer of ADP-ribose groups from NAD+ onto several target proteins. In vitro, ADP-ribosylation by ART2 activates the P2X7 ATP receptor and is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb733835da0e6327a7432aae7d736dd0
https://doi.org/10.4049/jimmunol.179.1.186
https://doi.org/10.4049/jimmunol.179.1.186
Autor:
Peter Bannas, Friedrich Koch-Nolte, Maria Miksiewicz, Alexander Hann, Olivier Boyer, Michel Seman, Friedrich Buck, Cary MacMillan, Björn Rissiek, Stephan Menzel, Sophie Teege, Sahil Adriouch, Friedrich Haag, Marion Nissen
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2015, 5 (1), ⟨10.1038/srep08959⟩
Scientific Reports, Nature Publishing Group, 2015, 5 (1), ⟨10.1038/srep08959⟩
Control of immunologic tolerance and homeostasis rely on Foxp3+CD4+CD25+ regulatory T cells (Tregs) that constitutively express the high affinity receptor for Interleukin-2, CD25. Tregs proliferate in response to injections of IL-2/anti-IL-2 antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7fe57c7dc72efaf3749c8e0577a217e
https://hal-normandie-univ.archives-ouvertes.fr/hal-02376180/document
https://hal-normandie-univ.archives-ouvertes.fr/hal-02376180/document
Autor:
Stephan Menzel, Hans-Willi Mittrücker, Fernando Alberto Goldbaum, Mandy Unger, Friedrich Haag, Holger Rohde, Anna Marei Eichhoff, Klaus Aktories, Moritz Strysio, Lucas Schumacher, Vanesa Zylberman, Carsten Schwan, Vanina Alzogaray, Friedrich Koch-Nolte, Michel Seman, Kai Zhu, Johanna M. Brandner
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Scientific Reports
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Scientific Reports
The spore-forming gut bacterium Clostridium difficile is the leading cause of antibiotic-associated diarrhea in hospitalized patients. The major virulence factors are two large glucosylating cytotoxins. Hypervirulent strains (e.g. ribotype 027) with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ded65bc2159ccc4453c39d2bc6dd6e
https://doi.org/10.1038/srep07850
https://doi.org/10.1038/srep07850