Zobrazeno 1 - 10
of 373
pro vyhledávání: '"Michel, Roberge"'
Autor:
Jonathan Frew, Alireza Baradaran-Heravi, Aruna D. Balgi, Xiujuan Wu, Tyler D. Yan, Steve Arns, Fahimeh S. Shidmoossavee, Jason Tan, James B. Jaquith, Karen R. Jansen-West, Francis C. Lynn, Fen-Biao Gao, Leonard Petrucelli, Howard H. Feldman, Ian R. Mackenzie, Michel Roberge, Haakon B. Nygaard
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-19 (2020)
Abstract Background Frontotemporal lobar degeneration (FTLD) is a devastating and progressive disorder, and a common cause of early onset dementia. Progranulin (PGRN) haploinsufficiency due to autosomal dominant mutations in the progranulin gene (GRN
Externí odkaz:
https://doaj.org/article/a734b9c2da774facb813e45baefeeee9
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103891- (2022)
Summary: Alport syndrome, a disease of kidney, ear, and eye, is caused by pathogenic variants in the COL4A3, COL4A4, or COL4A5 genes encoding collagen α3α4α5(IV) of basement membranes. Collagen IV chains that are truncated due to nonsense variants
Externí odkaz:
https://doaj.org/article/a879f32f26914813b12c4caa57e43e93
Autor:
Michel Roberge
This book presents the first comprehensive interpretation of the Paraphrase of Shem, Codex VII,1 in the Coptic Nag Hammadi Library. The lenghty introduction discusses the literary genre of the treatise, its plan and system, its situation among the Gn
Autor:
Sara Hosseini-Farahabadi, Alireza Baradaran-Heravi, Carla Zimmerman, Kunho Choi, Stephane Flibotte, Michel Roberge
Publikováno v:
PLoS Biology, Vol 19, Iss 5, p e3001221 (2021)
Premature termination codons (PTC) cause over 10% of genetic disease cases. Some aminoglycosides that bind to the ribosome decoding center can induce PTC readthrough and restore low levels of full-length functional proteins. However, concomitant inhi
Externí odkaz:
https://doaj.org/article/6c867feb7e4246c7815da789e71e9712
Autor:
Ewa H. Orlikowska, Johan Svensson, Jean-Michel Roberge, Malgorzata Blicharska, Grzegorz Mikusiński
Publikováno v:
Global Ecology and Conservation, Vol 22, Iss , Pp - (2020)
Biodiversity conservation often requires a landscape perspective. When establishing the Natura 2000 (N2k) network, the effectiveness of the sites and the influence of the surrounding landscapes for species of interest was often disregarded. We analyz
Externí odkaz:
https://doaj.org/article/71de2bde7efb4771b58167b0ef67887e
Autor:
Edward J. Morris, Eiko Kawamura, Jordan A. Gillespie, Aruna Balgi, Nagarajan Kannan, William J. Muller, Michel Roberge, Shoukat Dedhar
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Cancer cells have amplified centrosomes and deal with this abnormality by clustering them together so that they can be segregated in daughter cells. Here the authors perform a screening looking for inhibitors of this clustering process and find that
Externí odkaz:
https://doaj.org/article/58af0d7ff4e94bbd92f3feae3e7e8595
Supplementary Figure 3 from Caspase-3–Dependent Mitotic Checkpoint Inactivation by the Small-Molecule Inducers of Mitotic Slippage SU6656 and Geraldol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94a2bb2ba4814e1b45537adb06fc498
https://doi.org/10.1158/1535-7163.22497117.v1
https://doi.org/10.1158/1535-7163.22497117.v1
Supplementary Figure 2 from Caspase-3–Dependent Mitotic Checkpoint Inactivation by the Small-Molecule Inducers of Mitotic Slippage SU6656 and Geraldol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bf642759f76713dc57f1c0c945607d
https://doi.org/10.1158/1535-7163.22497120.v1
https://doi.org/10.1158/1535-7163.22497120.v1
Microtubule-targeting cancer drugs such as paclitaxel block cell-cycle progression at mitosis by prolonged activation of the mitotic checkpoint. Cells can spontaneously escape mitotic arrest and enter interphase without chromosome segregation by a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88e9fcc4f0576b290351d853513f049a
https://doi.org/10.1158/1535-7163.c.6535503
https://doi.org/10.1158/1535-7163.c.6535503
Supplementary Figure and Table Legends from Caspase-3–Dependent Mitotic Checkpoint Inactivation by the Small-Molecule Inducers of Mitotic Slippage SU6656 and Geraldol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0adf5447b68e87e98f62b11db850dd33
https://doi.org/10.1158/1535-7163.22497114.v1
https://doi.org/10.1158/1535-7163.22497114.v1