The Warburg Effect in Yeast: Repression of Mitochondrial Metabolism Is Not a Prerequisite to Promote Cell Proliferation

Autor: Cyrielle L. Bouchez, Noureddine Hammad, Sylvain Cuvellier, Stéphane Ransac, Michel Rigoulet, Anne Devin

Publikováno v: Frontiers in Oncology, Vol 10 (2020)

O. Warburg conducted one of the first studies on tumor energy metabolism. His early discoveries pointed out that cancer cells display a decreased respiration and an increased glycolysis proportional to the increase in their growth rate, suggesting th

Externí odkaz: https://doaj.org/article/f8903871a0e542a895179753d2b21f5c

Electrochemical analysis of the quinones redox state in isolated mitochondria from Saccharomyces cerevisiae

Autor: Mélanie Martins Pinto, Patrick Paumard, Michel Rigoulet, Stéphane Arbault, Anne Devin

Publikováno v: Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1863:148755

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14125d31b979b65b9d9e8fda85c5771a
https://doi.org/10.1016/j.bbabio.2022.148755

Cell energy metabolism: An update

Autor: Patrick Paumard, Stéphane Duvezin-Caubet, Sylvain Cuvellier, Jean-Pierre Mazat, Cyrielle Bouchez, Anne Devin, Stéphane Ransac, Michel Rigoulet

Publikováno v: Biochimica biophysica acta (BBA)-Bioenergetics
Biochimica biophysica acta (BBA)-Bioenergetics, Elsevier, 2020, 1861 (11), pp.148276. ⟨10.1016/j.bbabio.2020.148276⟩

International audience; In living cells, growth is the result of coupling between substrate catabolism and multiple metabolic processes that take place during net biomass formation and maintenance processes. During growth, both ATP/ADP and NADH/NAD +

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88ebc4340dc5960aca3ad135f8acae1
https://hal.archives-ouvertes.fr/hal-03009852

The role of glycolysis-derived hexose phosphates in the induction of the Crabtree effect

Autor: Noureddine Hammad, Razanne Issa, Alexis Mougeolle, Elodie Roussarie, Mónica Rosas Lemus, Stéphane Ransac, Salvador Uribe-Carvajal, Michel Rigoulet, Anne Devin, Jean-Pierre Mazat

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2018, 293 (33), pp.12843-12854. ⟨10.1074/jbc.RA118.003672⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2018, 293 (33), pp.12843-12854. ⟨10.1074/jbc.RA118.003672⟩

Evidence for the Crabtree effect was first reported by H. Crabtree in 1929 and is defined as the glucose-induced decrease of cellular respiratory flux. This effect was observed in tumor cells and was not detected in most non-tumor cells. A number of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf96db0cb4a8b88e98643562f5b24be
https://doi.org/10.1074/jbc.ra118.003672

'Labile' heme critically regulates mitochondrial biogenesis through the transcriptional co-activator Hap4p in

Autor: Cyrielle L, Bouchez, Edgar D, Yoboue, Livier E, de la Rosa Vargas, Bénédicte, Salin, Sylvain, Cuvellier, Michel, Rigoulet, Stéphane, Duvezin-Caubet, Anne, Devin

Publikováno v: J Biol Chem

Heme (iron protoporphyrin IX) is a well-known prosthetic group for enzymes involved in metabolic pathways such as oxygen transport and electron transfer through the mitochondrial respiratory chain. However, heme has also been shown to be an important

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5796af8933f6e82b3996810411b4a8e7
https://pubmed.ncbi.nlm.nih.gov/32075909