Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Michel, Lauzon"'
Autor:
Vanessa Plouffe, Nguyen-Vi Mohamed, Jessica Rivest-McGraw, Johanne Bertrand, Michel Lauzon, Nicole Leclerc
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36873 (2012)
It is well established that tau pathology propagates in a predictable manner in Alzheimer's disease (AD). Moreover, tau accumulates in the cerebrospinal fluid (CSF) of AD's patients. The mechanisms underlying the propagation of tau pathology and its
Externí odkaz:
https://doaj.org/article/b45e93e0ccc849088cd3a00359c783f9
Autor:
Angela Anton, Alain Guimont, Mylène Desjardins, Dalinda Liazoghli, Nicole Leclerc, Jacques Paiement, Sébastien Perreault, Carole Abi Farah, Michel Lauzon, Gert Kreibich
Publikováno v:
Journal of Biological Chemistry. 280:9439-9449
Neurons are polarized cells presenting two distinct compartments, dendrites and an axon. Dendrites can be distinguished from the axon by the presence of rough endoplasmic reticulum (RER). The mechanism by which the structure and distribution of the R
Autor:
Minh Dang Nguyen, Michel Lauzon, Sylvie Cornibert, Dave Bélanger, Nicole Leclerc, Carole Abi Farah
Publikováno v:
Journal of Cell Science. 115:1523-1539
The expression of microtubule-associated protein 2 (MAP2), developmentally regulated by alternative splicing, coincides with neurite outgrowth. MAP2 proteins contain a microtubule-binding domain (C-terminal) that promotes microtubule assembly and a p
Publikováno v:
Biology of Reproduction. 62:1505-1514
In the testis, the base of the Sertoli cells is in contact with the basement membrane matrix, in which the laminins constitute the major noncollagenous components. We have previously demonstrated that antibodies against a preparation enriched in base
Autor:
Moïse Bendayan, Albert H. Soloway, Robert A. Fenstermaker, Jacek Capala, Dianne M. Adams, Michel Lauzon, Jorgen Carlsson, Rolf F. Barth
Publikováno v:
Bioconjugate Chemistry. 7:7-15
In order for boron neutron capture therapy (BNCT) to be successful, a large number (approximately 10(9)) of 10B atoms must be delivered to each cancer cell in order to sustain a lethal 10B(n, alpha)7Li reaction. The majority of high grade gliomas exp
Autor:
Emilie Trillaud-Doppia, Catherine Bourgeois, Jannic Boehm, Siddhartha Mondragón-Rodríguez, Michel Lauzon, Nicole Leclerc, Anthony Dudilot
Amyloid-β and tau protein are the two most prominent factors in the pathology of Alzheimer disease. Recent studies indicate that phosphorylated tau might affect synaptic function. We now show that endogenous tau is found at postsynaptic sites where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ce62ead43390a696490278dfc863cf
https://europepmc.org/articles/PMC3442535/
https://europepmc.org/articles/PMC3442535/
Autor:
Nguyen-Vi Mohamed, Vanessa Plouffe, Jessica Rivest-McGraw, Johanne Bertrand, Michel Lauzon, Nicole Leclerc
Publikováno v:
Alzheimer's & Dementia. 8
Publikováno v:
Journal of neuropathology and experimental neurology. 68(5)
In several neurodegenerative diseases, including Alzheimer disease, the neuronal microtubule-associated protein tau becomes hyperphosphorylated, accumulates in the somatodendritic compartment, and aggregates into insoluble filaments. The consequences
Autor:
Angela Anton, Nicole Leclerc, Jacques Paiement, Michel Lauzon, Mylène Desjardins, Sébastien Perreault, Dalinda Liazoghli, Carole Abi Farah
Publikováno v:
Cell motility and the cytoskeleton. 63(11)
Tau, a microtubule-associated protein enriched in the axon, is known to stabilize and promote the formation of microtubules during axonal outgrowth. Several studies have reported that tau was associated with membranes. In the present study, we furthe
Autor:
Carole Abi, Farah, Dalinda, Liazoghli, Sébastien, Perreault, Mylène, Desjardins, Alain, Guimont, Angela, Anton, Michel, Lauzon, Gert, Kreibich, Jacques, Paiement, Nicole, Leclerc
Publikováno v:
The Journal of biological chemistry. 280(10)
Neurons are polarized cells presenting two distinct compartments, dendrites and an axon. Dendrites can be distinguished from the axon by the presence of rough endoplasmic reticulum (RER). The mechanism by which the structure and distribution of the R